Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Noburu Isono"'
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90580 (2014)
The thermal stability and topology of non-canonical structures of G-quadruplexes and hairpins in template DNA were investigated, and the effect of non-canonical structures on transcription fidelity was evaluated quantitatively. We designed ten templa
Externí odkaz:
https://doaj.org/article/4fcb70a1470b4663a7572dc22e4e29e9
Publikováno v:
Chembiochem : a European journal of chemical biology. 12(12)
Various nucleic acid structures other than just the duplex structure play important roles in binding to proteins in cellular systems and in functional nanodevices. The G-quadruplex structure, which consists of four strands of guanine-rich base sequen
Publikováno v:
Biochimie. 93(8)
The thrombin-binding DNA aptamer (TBA) 5'-d(GGTTGGTGTGGTTGG)-3' forms a G-quadruplex that is necessary for binding to the coagulation factor thrombin. The stability of the G-quadruplex of TBA when bound to thrombin and potassium ion (K(+)) were inves