Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Nobuo Sekiguchi"'
Autor:
Shumpei Ozawa, Satoshi Miki, Fumiaki Kimura, Yuji Kisaka, Yoshikazu Takahashi, Shinichi Tashiro, Nobuo Sekiguchi, Tomone Suwa, Manabu Tanaka
Publikováno v:
Metallurgical and Materials Transactions A. 52:5293-5299
TIG welding of high manganese stainless steels was conducted with different sulfur contents of 5 and 20 ppm. The penetration depth of the welding bead clearly increased even when the sulfur content of the sample was only very slightly increased from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b73a0c3d815a04e2748f6bac2f8a5cbf
https://doi.org/10.1007/s11661-021-06468-2
https://doi.org/10.1007/s11661-021-06468-2
Autor:
Hidetoshi Shindoh, Motohiro Kato, Nobuo Sekiguchi, Kenji Takanashi, Akihisa Kaneko, Keiichi Morita, Shunsuke Nagao, Masaki Ishigai
Publikováno v:
Xenobiotica. 47:1042-1051
1. A novel selective anaplastic lymphoma kinase (ALK) inhibitor, alectinib, has shown remarkable efficacy and safety in patients with ALK-positive non-small-cell lung cancer (NSCLC). The purpose of this study was to evaluate in vitro the potential to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::081de75058944d6147f3ca76620fffb8
https://doi.org/10.1080/00498254.2016.1261308
https://doi.org/10.1080/00498254.2016.1261308
Autor:
Tomone Suwa, Y. Takahashi, Y. Nabara, M. Oshikiri, K. Shibutani, Yoshihiko Nunoya, Nobuo Sekiguchi, Hidemitsu Matsuda, Fumiaki Tsutsumi
Publikováno v:
IEEE Transactions on Applied Superconductivity. 26:1-5
The International Thermonuclear Experimental Reactor (ITER) magnet system is composed of four kinds of large superconducting magnets. Those magnets are manufactured by using cable-in-conduit conductors (CICCs). In the production process of the CICCs,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62216b9604a0d15e9dc8a1512c1fb518
https://doi.org/10.1109/tasc.2016.2543465
https://doi.org/10.1109/tasc.2016.2543465
Autor:
Chiyomi Kubo, Akira Takeiri, Futa Mimoto, Naoaki Murao, Shunsuke Ito, Shotaro Takata, Atsuhiko Maeda, Masaki Ishigai, Kumiko Muraoka, Yuki Iwayanagi, Ayako Takahashi, Nobuo Sekiguchi, Shuichi Chiba, Mariko Yano, Tetsuya Wakabayashi
Publikováno v:
mAbs. 10(8)
Immunogenicity is a key factor capable of influencing the efficacy and safety of therapeutic antibodies. A recently developed method called MHC-associated peptide proteomics (MAPPs) uses liquid chromatography/mass spectrometry to identify the peptide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58007c5ed97d97a87fc224910c5653f8
https://pubmed.ncbi.nlm.nih.gov/30199322
https://pubmed.ncbi.nlm.nih.gov/30199322
Autor:
Y. Nabara, Yoshihiko Nunoya, Fumiaki Tsutsumi, O. Teshima, Y. Takahashi, Kunihiro Matsui, Y. Uno, K. Shibutani, Hidemasa Ozeki, M. Oshikiri, Nobuo Sekiguchi, Kiyoshi Okuno, Tsutomu Hemmi, Takaaki Isono, M. Kanaya, Tomone Suwa, K. Kawano
Publikováno v:
IEEE Transactions on Applied Superconductivity. 25:1-4
The Japan Atomic Energy Agency is responsible for procuring all amounts of central solenoid (CS) conductors for International Thermonuclear Experimental Reactor, including CS jacket sections. The conductor is cable-in-conduit conductor with a central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::636d00a24a64e166bef2c4b3d23e3aac
https://doi.org/10.1109/tasc.2014.2364632
https://doi.org/10.1109/tasc.2014.2364632
Autor:
Tomone Suwa, Hideki Kajitani, Tsutomu Hemmi, Takeru Sakurai, Yukinobu Murakami, Tsuyoshi Takano, Fumiaki Tsutsumi, Kiyoshi Okuno, Y. Takahashi, Y. Uno, Kunihiro Matsui, Hidemasa Ozeki, Takaaki Isono, M. Oshikiri, Norikiyo Koizumi, K. Shibutani, Nobuo Sekiguchi, Y. Nabara, Yoshihiko Nunoya, Hidemitsu Matsuda, Masahide Iguchi
Publikováno v:
IEEE Transactions on Applied Superconductivity. 25:1-5
We describe herein the characteristics of a Nb 3 Sn cable inserted into a conduit (cable-in-conduit conductor) for the International Thermonuclear Experimental Reactor toroidal field (TF) coil and central solenoid (CS). During insertion, the pulling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2a07867940f8e69ccc96f4af7891a1e
https://doi.org/10.1109/tasc.2014.2360562
https://doi.org/10.1109/tasc.2014.2360562
Autor:
Kazuki Shimizu, Tadakatsu Takahashi, Hideki Sato, Fumihiko Ichikawa, Shigeyuki Iijima, Suguru Harada, Nobuo Sekiguchi, Yoshiyuki Ono, Hirotaka Kashiwagi, Masaki Ishigai, Susumu Ito, Tsuyoshi Haneishi, Takamitsu Kobayashi
Publikováno v:
Bioorganic & Medicinal Chemistry. 19:4721-4729
Novel vitamin D3 analogs with carboxylic acid were explored, focusing on a nonsecosteroidal analog, LG190178, with a bisphenyl skeleton. From X-ray analysis of these analogs with vitamin D receptor (VDR), the carboxyl groups had very unique hydrogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d1b5e09e8d5b3aaa4924a3e3e54d262
https://doi.org/10.1016/j.bmc.2011.07.001
https://doi.org/10.1016/j.bmc.2011.07.001
Autor:
Hiroo Watanabe, Tetsuya Mitsui, Motohiro Kato, Maiko Takada, Shotaro Takata, Nobuo Sekiguchi, Yoshinori Aso, Masaki Ishigai
Publikováno v:
Drug Metabolism and Disposition. 39:1255-1262
It was previously demonstrated that mibefradil, which shows mechanism-based inhibition in humans, also caused drug-drug interactions (DDIs) with midazolam (MDZ) in rats. In this study, we aimed to quantitatively predict the DDIs observed in rats usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c0b3233cd2faf18bd0a036617b85496
https://doi.org/10.1124/dmd.110.037903
https://doi.org/10.1124/dmd.110.037903
Autor:
Yoshinori Aso, Masaki Ishigai, Kenji Takanashi, Motohiro Kato, Tetsuya Mitsui, Nobuo Sekiguchi, Atsuko Higashida, Yoshiaki Nabuchi
Publikováno v:
Drug Metabolism and Pharmacokinetics. 24:500-510
Summary: A method of assessing the risk of drug-drug interaction (DDI) caused by mechanism-based inhibition (MBI) was developed for early-stage drug development using cytochrome P450 (CYP) 3A4 inhibition screening data. CYP3A4 inhibition was evaluate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57a1f9faee2b8b52180c4d55e9729bb9
https://doi.org/10.2133/dmpk.24.500
https://doi.org/10.2133/dmpk.24.500
Autor:
Motohiro Kato, H. Watanabe, Yoshinori Aso, Maiko Takada, Masaki Ishigai, Atsuko Higashida, S. Sakai, Nobuo Sekiguchi
Publikováno v:
Xenobiotica. 38:368-381
1. There have been no reports showing that the area under the concentration-time curve (AUC) of a probe drug is elevated due to mechanism-based inhibition (MBI) of drug-metabolizing enzymes in animals. This study ascertained that mechanism-based inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c015221974018f5b0057fc8acf9923d3
https://doi.org/10.1080/00498250701851891
https://doi.org/10.1080/00498250701851891