Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Nobuo Nyui"'
Autor:
Satoshi Umemura, Kouichi Tamura, Minoru Kihara, Tomoaki Ishigami, Hisao Ochiai, Yuzuru Yoshii, Takayuki Fujita, Yasujirou Watanabe, Shunsaku Mizushima, Nobuo Nyui, Masami Kosuge, Masao Ishii, Kazuo Kimura, Kiyoshi Hibi
Publikováno v:
Hypertension. 32:521-526
Abstract —Recently a point mutation of guanine to thymine at nucleotide position 1917 in the endothelial nitric oxide synthase (eNOS) gene has been reported to be associated with coronary artery spasm. In addition, a significant association of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6077b01058def1f118aeb273752580c
https://doi.org/10.1161/01.hyp.32.3.521
https://doi.org/10.1161/01.hyp.32.3.521
Autor:
Akiyoshi Fukamizu, Nobuo Nyui, Shunichi Kobayashi, Kouichi Tamura, Masao Ishii, Kazuo Murakami, Satoshi Umemura, Takeshi Sugaya, Hitoshi Miyazaki, Yoichi Sumida, Minoru Kihara, Tomoaki Ishigami
Publikováno v:
Hypertension. 32:223-227
Abstract —This study examined expression of renin-angiotensin system (RAS) component mRNAs in angiotensinogen gene knockout ( Atg −/−) mice. Wild-type ( Atg +/+) and Atg −/− mice were fed a normal-salt (0.3% NaCl) or high-salt (4% NaCl) die
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::968f5ee73336d8d58d52961cfb639d9c
https://doi.org/10.1161/01.hyp.32.2.223
https://doi.org/10.1161/01.hyp.32.2.223
Autor:
Kiyoshi Hibi, Satoshi Umemura, Yoshiyuki Toya, Minoru Kihara, Masao Ishii, Tomoaki Ishigami, Nobuo Nyui, Kouichi Tamura
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 275:R1-R9
Circulating and cardiac renin-angiotensin systems (RAS) play important roles in the development of cardiac hypertrophy. Mechanical stretch of cardiac myocytes induces secretion of ANG II and evokes hypertrophic responses. Angiotensinogen is a unique
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29e434a309679748d749d8cb847edd3e
https://doi.org/10.1152/ajpregu.1998.275.1.r1
https://doi.org/10.1152/ajpregu.1998.275.1.r1
Autor:
Nobuo Nyui, Masao Ishii, Yoichi Sumida, Machiko Yabana, Kazuo Murakami, Satoshi Umemura, R Kishida, Kadota T, Minoru Kihara, Akiyoshi Fukamizu, Kouichi Tamura
Publikováno v:
Journal of the American Society of Nephrology. 9:355-362
The present study investigates whether neuronal type nitric oxide synthase (N-NOS) in the macula densa participates in the regulation of renal renin expression during altered dietary salt intake in angiotensinogen gene-knockout (Atg-/-) mice. Wild-ty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f82b944d70f5d718d22c80e8dc68d538
https://doi.org/10.1681/asn.v93355
https://doi.org/10.1681/asn.v93355
Autor:
Machiko Yabana, Masao Ishii, Akiyoshi Fukamizu, Yoichi Sumida, Kazuo Murakami, Nobuo Nyui, Satoshi Umemura, Nobuyuki Yokoyama, Kouichi Tamura, Minoru Kihara
Publikováno v:
Kidney International. 53:548-555
Genetic deficiency of angiotensinogen produces an impaired urine concentrating ability in mice. Angiotensinogen gene-knockout ( Atg −/− ) mice lacking angiotensin II exhibit chronic hypotension. The present study was designed to investigate patho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bda098ff83357fd2894529c2a0dd3f19
https://doi.org/10.1046/j.1523-1755.1998.00801.x
https://doi.org/10.1046/j.1523-1755.1998.00801.x
Autor:
Machiko Yabana, Masao Ishii, Shunichi Kobayashi, Kazuo Murakami, Satoshi Umemura, Nobuo Nyui, Hitoshi Miyazaki, Akiyoshi Fukamizu, Tomoaki Ishigami, Kouichi Tamura, Minoru Kihara, Hisao Ochiai, Yoichi Sumida
Publikováno v:
Hypertension. 31:45-49
Abstract —Two subtypes of angiotensin II (Ang II) receptors, type 1 (AT 1 -R) and type 2 (AT 2 -R), have been identified in the heart. However, little is known about the regulation of cardiac AT 1 -R and AT 2 -R by Ang II in vivo. Thus, we examined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::876d80da30003abd4868bbea9edbf73b
https://doi.org/10.1161/01.hyp.31.1.45
https://doi.org/10.1161/01.hyp.31.1.45
Autor:
Satoshi Yamaguchi, Masao Ishii, Machiko Yabana, Akiyoshi Fukamizu, Minoru Kihara, Kazuo Murakami, Satoshi Umemura, Kouichi Tamura, Kiyoshi Hibi, Nobuo Nyui, Tomoaki Ishigami
Publikováno v:
Journal of Biological Chemistry. 272:16845-16851
The protein product of the retinoblastoma susceptibility gene, RB, is a nuclear phosphoprotein that modulates transcription of genes involved in growth control via interactions with transcription factors. Renin is a rate-limiting enzyme of the renin-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::615def71ecc57de5222f9ddd2a96fd47
https://doi.org/10.1074/jbc.272.27.16845
https://doi.org/10.1074/jbc.272.27.16845
Autor:
Nobuo Nyui, Eiko Chiba, Nobuyuki Yokoyama, Kouichi Tamura, Machiko Yabana, Tomoaki Ishigami, Kiyoshi Hibi, Daisukc Takahashi, Toshiaki Ushikubo, Akihiko Moriya, Satoshi Umemura, Masao Ishii, Masakazu Tomiyama
Publikováno v:
Life Sciences. 60:1623-1633
Recent association and linkage studies suggested that angiotensinogen may play an important role in the pathogcnasis of essential hypertension. However, there is little information in human concerning a relationship between plasma angiotensinogen lev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::550e117f880632216fe5284862f6c8e6
https://doi.org/10.1016/s0024-3205(97)00129-x
https://doi.org/10.1016/s0024-3205(97)00129-x
Autor:
Kazuo Murakami, Satoshi Umemura, Nobuo Nyui, Tadashi Yamakawa, Shun-ichi Tanaka, Kouichi Tamura, Tomoaki Ishigami, Nobuyoshi Takagi, Masao Ishii, Hisahiko Sekihara, Satoshi Yamaguchi, Keiji Tanimoto
Publikováno v:
Hypertension. 27:1216-1223
Abstract Angiotensinogen is expressed in many tissues besides the liver. Recent studies have suggested that abnormalities in the regulation of angiotensinogen gene expression may be involved in the development of hypertension. However, little informa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b6741a3c2d0a5c29fa1a58b207dd85f
https://doi.org/10.1161/01.hyp.27.6.1216
https://doi.org/10.1161/01.hyp.27.6.1216
Autor:
Kousuke Minamisawa, Yoshitaka Hayashi, Yasumasa Fujiwara, Masato Sawano, Osamu Yamanaka, Riichiro Nakayama, Shinji Suzuki, Tai Nakamura, Shinichiro Yamagami, Masanori Nemoto, Nobuo Nyui, Atsushi Wada
Publikováno v:
Circulation journal : official journal of the Japanese Circulation Society. 66(5)
Coronary artery calcification (CAC) was assessed by cinefluoroscopy and its extent was scored (CAC score) in 2,163 consecutive patients undergoing coronary angiography, based on the angiographic and clinical data, the patients were categorized into 8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c09e9462c7c4898bb9f2895f7a21ec87
https://pubmed.ncbi.nlm.nih.gov/12030343
https://pubmed.ncbi.nlm.nih.gov/12030343