Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Nobuo Nemoto"'
Publikováno v:
Drug Metabolism and Pharmacokinetics. 48:100485
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1efe6de0c7fb93536f76b8008a6dca7
https://doi.org/10.1016/j.dmpk.2022.100485
https://doi.org/10.1016/j.dmpk.2022.100485
Publikováno v:
Pharmaceutical Biology. 50:1007-1012
Diabetes mellitus (DM), a chronic disease, has been increasing and subsequently devastates the quality of life and economic status of the patients. Oxidative stress participates in development and progression of diabetes, in which levels of glutathio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::569c260803d2ae0623f9325b96503f3f
https://doi.org/10.3109/13880209.2012.655377
https://doi.org/10.3109/13880209.2012.655377
Publikováno v:
Chemico-Biological Interactions. 196:23-29
Berberine, an isoquinoline alkaloid isolated from medicinal plants such as Berberis aristata, Coptis chinesis, Coptis japonica, Coscinium fenestatun, and Hydrastis Canadensis, is widely used in Asian countries for the treatment of diabetes, hypertens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00e1616b94a96443f3bdfb471d1fa582
https://doi.org/10.1016/j.cbi.2012.01.006
https://doi.org/10.1016/j.cbi.2012.01.006
Publikováno v:
Fitoterapia. 82:889-895
Impacts of berberine, a major isoquinoline alkaloid in herbal plants, on beta-naphthoflavone (BNF)-induced CYP1A expression were determined both in primary mouse hepatocytes and in vivo. Berberine concentration-dependently suppressed BNF-induced CYP1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dea5329970ff23b360aabe94bdbb13e
https://doi.org/10.1016/j.fitote.2011.05.002
https://doi.org/10.1016/j.fitote.2011.05.002
Publikováno v:
Toxicology. 280:18-23
We previously reported that andrographolide (Andro), a major bioactive constituent of Andrographis paniculata, synergistically enhanced the inducible expression of CYP1A1 mRNA. In this study, although the synergism was confirmed at 24h after the star
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca6ea7f0457d1855c5bfe376a5f76a2d
https://doi.org/10.1016/j.tox.2010.11.002
https://doi.org/10.1016/j.tox.2010.11.002
Publikováno v:
Drug Metabolism and Disposition. 39:490-497
CYP3A41 is a female-specific cytochrome P450 in mouse liver. A putative hepatocyte nuclear factor 4α (HNF4α)-binding site was found at -99/-87 in the promoter of Cyp3a41 by reporter assays performed in the hepatocytes of female mice. Cotransfection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4df564f8fa8bebf55e596257a705cf3
https://doi.org/10.1124/dmd.110.035980
https://doi.org/10.1124/dmd.110.035980
Autor:
Yuki Kawasaki, Waranya Chatuphonprasert, Sachiko Kondo, Nobuo Nemoto, Tsutomu Sakuma, Kanokwan Jarukamjorn
Publikováno v:
European Journal of Pharmaceutical Sciences. 39:394-401
We previously observed a strong synergistic effect on polycyclic aromatic hydrocarbon (PAH)-induced CYP1A1 expression by andrographolide, a major constituent of an herbal medicine derived from the plant Andrographis paniculata, in mouse hepatocytes i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::902d1b2bb727797d886f0cc92265e98e
https://doi.org/10.1016/j.ejps.2010.01.009
https://doi.org/10.1016/j.ejps.2010.01.009
Publikováno v:
Chemico-Biological Interactions. 182:233-238
We previously reported that andrographolide greatly enhanced the expression of CYP1A1. Since andrographolide is a major constituent of Andrographis paniculata, which has been employed for centuries in Asia and Europe as a folk remedy, we further anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6e18de6405f1b377fb9278db3df9a35
https://doi.org/10.1016/j.cbi.2009.09.001
https://doi.org/10.1016/j.cbi.2009.09.001
Publikováno v:
Journal of Health Science. 55:325-337
Sex differences have been found in the pharmacokinetics of many drugs, and sex differences of drug-metabolizing enzymes have been considered one of the major factors of this issue. Cytochrome P450, a Phase I drug-metabolizing enzyme, consists of many
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5427582ab93a7637f9965b94eeb0a70
https://doi.org/10.1248/jhs.55.325
https://doi.org/10.1248/jhs.55.325
Autor:
Yuki Kawasaki, Akiko Takase, Sachiko Kondo, Nobuo Nemoto, Atika Jaruchotikamol, Sumiyo Itoh, Tsutomu Sakuma
Publikováno v:
Journal of Health Science. 55:767-776
The present study investigated issues regarding cytotoxicity tests using mouse hepatocytes in primary culture. The results indicated that the cytotoxicity of acetaminophen (APAP) markedly varied depending on culture period for up to 5 days. P450 isof
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4f41894c079e3c451f760e812103e6f
https://doi.org/10.1248/jhs.55.767
https://doi.org/10.1248/jhs.55.767