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Akademický článek

Novel Situations of Endothelial Injury in Stroke — Mechanisms of Stroke and Strategy of Drug Development: Intracranial Bleeding Associated With the Treatment of Ischemic Stroke: Thrombolytic Treatment of Ischemia-Affected Endothelial Cells With Tissue-Type Plasminogen Activator

Autor: Yasuhiro Suzuki, Nobuo Nagai, Kazuo Umemura

Publikováno v: Journal of Pharmacological Sciences, Vol 116, Iss 1, Pp 25-29 (2011)

Abstract.: Previous studies have shown that the risk of intracranial hemorrhage (ICH) associated with the treatment of ischemic stroke is mainly attributable to antithrombotic agents. On the basis of clinical trials, only tissue-type plasminogen acti

Externí odkaz: https://doaj.org/article/dba013d689204e4daaa07af3e36f1f4b

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Akademický článek

Human Dynactin-Associated Protein Transforms NIH3T3 Cells to Generate Highly Vascularized Tumors with Weak Cell-Cell Interaction.

Autor: Tatsuki Kunoh, Weixiang Wang, Hiroaki Kobayashi, Daisuke Matsuzaki, Yuki Togo, Masahiro Tokuyama, Miho Hosoi, Koichi Koseki, Shu-Ichi Wada, Nobuo Nagai, Toshinobu Nakamura, Shintaro Nomura, Makoto Hasegawa, Ryuzo Sasaki, Tamio Mizukami

Publikováno v: PLoS ONE, Vol 10, Iss 8, p e0135836 (2015)

Human dynactin-associated protein (dynAP) is a transmembrane protein that promotes AktSer473 phosphorylation. Here, we report the oncogenic properties of dynAP. In contrast to control NIH3T3 cells expressing LacZ (NIH3T3LacZ), NIH3T3dynAP cells vigor

Externí odkaz: https://doaj.org/article/0ccf4a4d32ed447a9990bf8f709a722c

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Akademický článek

In vivo diagnostic imaging using micro-CT: sequential and comparative evaluation of rodent models for hepatic/brain ischemia and stroke.

Autor: Naoto Hayasaka, Nobuo Nagai, Naoyuki Kawao, Atsuko Niwa, Yoshichika Yoshioka, Yuki Mori, Hiroshi Shigeta, Nobuo Kashiwagi, Masaaki Miyazawa, Takao Satou, Hideaki Higashino, Osamu Matsuo, Takamichi Murakami

Publikováno v: PLoS ONE, Vol 7, Iss 2, p e32342 (2012)

BackgroundThere is an increasing need for animal disease models for pathophysiological research and efficient drug screening. However, one of the technical barriers to the effective use of the models is the difficulty of non-invasive and sequential m

Externí odkaz: https://doaj.org/article/7bd320566cff43028d230c3d26a5c7b4

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Akademický článek

Circuit Theory Based on New Concepts and Its Application to Quantum Theory: 33. Hypothetic Mathematical Definitions Setting on Unit Elements Derived from Coaxial Cables.

Autor: Nobuo Nagai, Hirofumi Sanada

Publikováno v: Journal of Signal Processing (1342-6230); Sep2024, Vol. 28 Issue 5, p249-255, 7p

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Akademický článek

Circuit Theory Based on New Concepts and Its Application to Quantum Theory: 30. Ideas of Heaviside for Electromagnetic Wave Derived from Maxwell Equations Reformulated by Heaviside.

Autor: Nobuo Nagai, Hirofumi Sanada, Takashi Yahagi

Publikováno v: Journal of Signal Processing (1342-6230); Jan2024, Vol. 28 Issue 1, p29-35, 7p

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Inflammatory responses is induced in pulmonary embolic lung: evaluation by a reproducible pulmonary embolism model in mice

Autor: Honoka Okabe, Haruka Kato, Momoka Yoshida, Mayu Kotake, Ruriko Tanabe, Yasuki Matano, Masaki Yoshida, Shintaro Nomura, Atsushi Yamashita, Nobuo Nagai

BackgroundSince previously established models of pulmonary embolism showed a large variability in the degree of ischemia, it is difficult to assess the pathophysiological response in the lung after embolization. Here, we established a model of pulmon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8fd3006719b9a06cc02a6c57a34f80c7
https://doi.org/10.1101/2022.07.29.501960

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