Výsledky vyhledávání

Lentivector Transduction Improves Outcomes Over Transplantation of Human HSCs Alone in NOD/SCID/Fabry Mice

Autor: Makoto Yoshimitsu, Jeffrey A. Medin, Nobuo Mizue, Toshihiro Takenaka, Natalia Pacienza, Xin Fan, James C.M. Wang, Bryan Au

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Fabry disease is a lysosomal storage disorder caused by a deficiency of a-galactosidase A (a-gal A) activity that results in progressive globotriaosylceramide (Gb(3)) deposition. We created a fully congenic nonobese diabetic (NOD)/severe combined imm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f336af36da45b23a097c0955b1603d6
https://doi.org/10.1038/mt.2012.64

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Extensive gene deletions in Japanese patients with Diamond-Blackfan anemia

Publikováno v: Blood. 119:2376-2384

Fifty percent of Diamond-Blackfan anemia (DBA) patients possess mutations in genes coding for ribosomal proteins (RPs). To identify new mutations, we investigated large deletions in the RP genes RPL5, RPL11, RPL35A, RPS7, RPS10, RPS17, RPS19, RPS24,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30b0d87c07eff0f03c412273c2527cff
https://doi.org/10.1182/blood-2011-07-368662

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An evaluation of peripherally inserted central venous catheters for children with cancer requiring long-term venous access

Autor: Nobuo Mizue, Masaki Yamamoto, Hiroyuki Tsutsumi, Tsukasa Hori, Natsuko Inazawa, Naoki Hatakeyama, Keita Igarashi, Nobuhiro Suzuki

Publikováno v: International Journal of Hematology. 94:372-377

Long-term venous access is essential when treating malignant diseases. We reviewed our experience with peripherally inserted central venous catheters (PICC) in children suffering from various malignancies with regard to catheter life, reasons for rem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a543a9ec189c09f999044ec2f315394
https://doi.org/10.1007/s12185-011-0928-2

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Survival and Cardiac Remodeling After Myocardial Infarction Are Critically Dependent on the Host Innate Immune Interleukin-1 Receptor-Associated Kinase-4 Signaling

Autor: Nobuo Mizue, Peter Liu, Wen Chen Yeh, Youan Liu, Geoffrey De Couto, Annie Chan, Manyin Chen, Yu Shi, Steven Dawood, Yuichiro Maekawa, Fayez Dawood, Nobutaka Suzuki, Jeffrey A. Medin, Guo Hua Li, Anthony O. Gramolini

Publikováno v: Circulation. 120:1401-1414

Background— The innate immune system greatly contributes to the inflammatory process after myocardial infarction (MI). Interleukin-1 receptor-associated kinase-4 (IRAK-4), downstream of Toll/interleukin-1 receptor signaling, has an essential role i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d09abe87b5bfebd3cf857fae347eaaa2
https://doi.org/10.1161/circulationaha.109.865956

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Potent induction of B- and T-cell immunity against human carcinoembryonic antigen-expressing tumors in human carcinoembryonic antigen transgenic mice mediated by direct lentivector injection

Autor: Robert Kammerer, Nobuo Mizue, Jacopo Mariotti, Wolfgang Zimmermann, Severine Loisel-Meyer, Jason Foley, Miriam E. Mossoba, Boro Dropulic, Daniel H. Fowler, J. Andrea McCart, Tania C. Felizardo, Robert Keefe, Jeffrey A. Medin

Publikováno v: Molecular Cancer Therapeutics. 8:692-702

The applicability of immunotherapy would be dramatically broadened to a greater number of recipients if direct “off-the-shelf” products could be engineered to engender functionally potent immune responses against true “self”-tumor antigens. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92cfafbfa80d3b900a8f18915472c079
https://doi.org/10.1158/1535-7163.mct-08-0769

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Treatment of Stage IV Malignant Rhabdoid Tumor of the Kidney (MRTK) With ICE and VDCy

Autor: Toshinori Hirama, Takanori Oda, Nobuo Mizue, Masaki Yamamoto, Jeffrey S. Dome, Yuki Kuroiwa, Shigeaki Yokoyama, Nobuhiro Suzuki, Tsukasa Hori, Akihiro Nui, Takashi Matsuno, Hiroyuki Tsutsumi, Naoki Hatakeyama, Tooru Kudoh, Masato Hareyama

Publikováno v: Journal of Pediatric Hematology/Oncology. 28:286-289

The prognosis of stage IV malignant rhabdoid tumor of the kidney (MRTK) has been extremely poor. However, a combination of ICE (ifosfamide, carboplatin, and etoposide) and VDCy (vincristine, doxorubicin, and cyclophosphamide) was recently reported to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07aac8c1f85ca2c5d149913ff2b3c404
https://doi.org/10.1097/01.mph.0000212901.84146.5a

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Relapse of T-cell all after stem cell transplant presenting as hypertrophic cardiomyopathy: The value of non-invasive diagnostic imaging in detecting cardiac leukemia

Autor: Nobuhiro Suzuki, Motoki Takamuro, Hiroyuki Tsutsumi, Tsukasa Hori, Naoki Hatakeyama, Nobuo Mizue

Publikováno v: Pediatric Blood & Cancer. 46:108-111

We describe a 14-year-old female with acute lymphoblastic leukemia (ALL) with a mediastinal mass at diagnosis who developed hypertrophic cardiomyopathy (HC) after stem cell transplantation (SCT). During refractory relapse after SCT using bone marrow

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3d143229b91603676240a6d0b77d706
https://doi.org/10.1002/pbc.20409

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Successful induction of immune tolerance in a patient with haemophilia B with inhibitor

Autor: Tsukasa Hori, J. Watanabe, Nobuo Mizue, Hiroyuki Tsutsumi, Tooru Kudoh, Naoki Hatakeyama, Nobuhiro Suzuki, Takanori Oda

Publikováno v: Haemophilia. 9:340-342

Summary. We describe successful induction of immune tolerance (IT) in a 10-month-old boy with severe haemophilia B. Urticaria developed soon after starting prophylactic treatment and was associated with an inhibitor at 7 Bethesda units mL−1. Initia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1bb837000fff9da7f24f8a6daca475e9
https://doi.org/10.1046/j.1365-2516.2003.00754.x

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Treatment of McLeod phenotype chronic granulomatous disease with reduced-intensity conditioning and unrelated-donor umbilical cord blood transplantation

Autor: Masaki Yamamoto, Yuki Kuroiwa, Junko Takahashi, Minami Yoda, Yoshihiko Tani, Nobuhiro Suzuki, Hiroyuki Tsutsumi, Naoki Hatakeyama, Nobuo Mizue

Publikováno v: International journal of hematology. 85(1)

Patients with chronic granulomatous disease (CGD) complicated by antimycotics-refractory invasive aspergillosis have an extremely poor prognosis if they cannot undergo allogeneic hematopoietic stem cell transplantation from a suitable related donor w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b75590fd4fd8e2dd758b4b17f5426192
https://pubmed.ncbi.nlm.nih.gov/17261504

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