Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Nobuo Kugai"'
Publikováno v:
Journal of Bone and Mineral Research. 11:931-937
Formation of advanced glycation end products (AGEs) in extracellular matrix (ECM) is implicated in the development of chronic diabetic complications. However, the involvement of AGEs in diabetic bone disease has not been well established. We have exa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::204bb2bebc92137ea66db18118c567c8
https://doi.org/10.1002/jbmr.5650110709
https://doi.org/10.1002/jbmr.5650110709
Publikováno v:
Bone. 33:798-804
The inducible prostaglandin (PG) synthesis enzyme, cyclooxygenase-2 (COX-2), is involved in osteoclast (OC) formation in cocultures of mouse mammary cancer cell lines (MMT060562 or BALB/c-MC) and bone marrow cells through production of PGE 2 . There
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97b8c81b930e310e365afc7c14d44e75
https://doi.org/10.1016/s8756-3282(03)00264-3
https://doi.org/10.1016/s8756-3282(03)00264-3
Autor:
Mitsuo Itakura, Yoshinobu Koide, Toshiro Fujita, Yamashita N, Nobuo Kugai, Kamejiro Yamashita, H. Yamamura
Publikováno v:
Hormone and Metabolic Research. 16:204-206
A 59-year-old Japanese farmer with asymptomatic fasting hypoglycemia and with exaggerated hypoglycemic episodes induced by insulin and oral hypoglycemic agent administered for his postprandial hyperglycemia was diagnosed as glycogen storage disease t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc0861fd30e12d224e141838c4f42c90
https://doi.org/10.1055/s-2007-1014934
https://doi.org/10.1055/s-2007-1014934
Autor:
Miyuki Nishikawa, Mikio Yamamoto, Takehiko Murakami, Seiki Wada, Katsuhiro Ono, Takuhiko Akatsu, Naokazu Nagata, Nariaki Matsuura, Nobuo Kugai
Publikováno v:
Bone. 23:27-32
We recently reported that numerous osteoclasts (OC) were formed in cocultures of some mouse cancer cell lines and bone marrow cells. In this study, we examined mechanisms by which one of the cell lines, BALB/c-MC, induces OC. BALB/c-MC dose dependent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16e56846946d653a4babbd6063ba661e
https://doi.org/10.1016/s8756-3282(98)00065-9
https://doi.org/10.1016/s8756-3282(98)00065-9
Autor:
Miyuki Nishikawa, Michiko Yamamoto, Takehiko Murakami, Naokazu Nagata, Takuhiko Akatsu, Nobuo Kugai
Publikováno v:
Journal of Bone and Mineral Research. 13:986-995
The theory that bisphosphonates inhibit osteoclast formation through their effects on osteoblastic cells remains controversial. To confirm the inhibitory effect of bisphosphonates on osteoclast formation and gain some insights into the underlying mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::448b55f4ffab329bc2f7b249b8aa16a0
https://doi.org/10.1359/jbmr.1998.13.6.986
https://doi.org/10.1359/jbmr.1998.13.6.986
Autor:
Yasuyuki Katayama, Katsuhiro Ono, Tatsuya Tamura, Nobuo Kugai, Naokazu Nagata, Takuhiko Akatsu, Michiko Yamamoto, Miyuki Nishikawa
Publikováno v:
Journal of Bone and Mineral Research. 13:400-408
Osteoclastic bone resorption increases at the site of bone metastasis, but little is known about how tumor cells induce osteoclast (OC) recruitment in the bone marrow microenvironment. To clarify this point, we examined the effects of various mouse t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a426c34f731f2751aba71310ca3c8e55
https://doi.org/10.1359/jbmr.1998.13.3.400
https://doi.org/10.1359/jbmr.1998.13.3.400
Autor:
Terumasa Nagase, K. Tsuchiya, Ryohji Nakamura, Seiki Wada, Michiko Yamamoto, Naokazu Nagata, Takahiro Morisako, Keiko Kamakura, Nobuo Kugai
Publikováno v:
Internal Medicine. 34:554-558
A 64-year-old woman developed multiple brain abscesses of the basal ganglia associated with Klebsiella pneumoniae septicemia. Magnetic resonance (MR) images showed three different stages of the brain abscesses. The images of early cerebritis of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dafb6e4a0a86103cdabe603dd35ce81
https://doi.org/10.2169/internalmedicine.34.554
https://doi.org/10.2169/internalmedicine.34.554
Autor:
Akira Aoki, Yoko Nemoto, Michiko Yamamoto, Yoshirou Yasutomo, Nobuo Kugai, Yasuyuki Katayama, Seijirou Kado, Naokazu Nagata, Shintarou Terahata
Publikováno v:
Internal Medicine. 34:446-450
This case report describes a 68-year-old man with Cushing's syndrome due to adrenocorticotropic hormone (ACTH)-independent bilateral adrenocortical macronodular hyperplasia (AIMAH). He was referred to our hospital for evaluation of bilateral enlargem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6e0e0b140b58b80a8f0c5c1334dffc5
https://doi.org/10.2169/internalmedicine.34.446
https://doi.org/10.2169/internalmedicine.34.446
Publikováno v:
Endocrine Journal. 40:473-478
A case of isolated ACTH deficiency accompanying transient primary hypothyroidism was reported along with a review of literature on isolated ACTH deficiency in Japan with special reference to its association with thyroid function. Our case, a 56-year-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9ae28bfcee3d50deab10b41757f0e92
https://doi.org/10.1507/endocrj.40.473
https://doi.org/10.1507/endocrj.40.473
Publikováno v:
Internal Medicine. 32:611-618
To determine the changes in bone metabolism in response to combined chemotherapy in patients with bone metastases (BM), we examined osteocalcin (BGP), alkalinephosphatase (ALP), hydroxyproline (HYP), pyridinoline (PYR), and/or deoxypyridinoline (D-PY
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71e00e86fbb6a94911a99f9ab12f4f09
https://doi.org/10.2169/internalmedicine.32.611
https://doi.org/10.2169/internalmedicine.32.611