Zobrazeno 1 - 10
of 801
pro vyhledávání: '"Nobuo Kato"'
Publikováno v:
Journal of Physiological Sciences, Vol 74, Iss 1, Pp 1-15 (2024)
Abstract The balance of activity between glutamatergic and GABAergic networks is particularly important for oscillatory neural activities in the brain. Here, we investigated the roles of GABAB receptors in network oscillation in the oral somatosensor
Externí odkaz:
https://doaj.org/article/0fe5da6a678348a29605297ee5c0f4ba
Autor:
Munenori Ono, Tetsufumi Ito, Sachiko Yamaki, Yoshie Hori, Qing Zhou, Xirun Zhao, Shinji Muramoto, Ryo Yamamoto, Takafumi Furuyama, Hiromi Sakata-Haga, Toshihisa Hatta, Tsuyoshi Hamaguchi, Nobuo Kato
Publikováno v:
Heliyon, Vol 10, Iss 7, Pp e28821- (2024)
The amyloid plaque is a hallmark of Alzheimer's disease. The accumulation of the amyloid precursor protein (APP) in the neuronal structure is assumed to lead to amyloid plaque formation through the excessive production of β-amyloid protein. To study
Externí odkaz:
https://doaj.org/article/b8c6b5b2aa2e4ea190e21854fd2c4b22
Autor:
Takafumi Furuyama, Ayana Imayoshi, Toyo Iyobe, Munenori Ono, Tatsuya Ishikawa, Noriyuki Ozaki, Nobuo Kato, Ryo Yamamoto
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Shifting defensive mode from one to another by the imminence of threat is crucial for survival. The transition of defensive mode from freezing to flight is observed during the modified fear conditioning, however, the flight during fear condi
Externí odkaz:
https://doaj.org/article/120ad3efdaf64d208dbf1f2b3f824850
Autor:
Tatsuya Ishikawa, Koshi Murata, Hiroaki Okuda, Ilia Potapenko, Kiyomi Hori, Takafumi Furuyama, Ryo Yamamoto, Munenori Ono, Nobuo Kato, Yugo Fukazawa, Noriyuki Ozaki
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106332- (2023)
Summary: The mechanism by which acute pain or itch information at the periphery is processed in the primary somatosensory cortex (S1) remains unclear. To elucidate this, we used a viral-mediated targeted-recombination-in-active population system to t
Externí odkaz:
https://doaj.org/article/89e87eadbe7f444c843ecf258cb96e9a
Autor:
Dinh Thi Nguyen, Thuong Manh Le, Tsuyoshi Hattori, Mika Takarada-Iemata, Hiroshi Ishii, Jureepon Roboon, Takashi Tamatani, Takayuki Kannon, Kazuyoshi Hosomichi, Atsushi Tajima, Shusuke Taniuchi, Masato Miyake, Seiichi Oyadomari, Takashi Tanaka, Nobuo Kato, Shunsuke Saito, Kazutoshi Mori, Osamu Hori
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract While ATF6α plays a central role in the endoplasmic reticulum (ER) stress response, the function of its paralogue ATF6β remains elusive, especially in the central nervous system (CNS). Here, we demonstrate that ATF6β is highly expressed i
Externí odkaz:
https://doaj.org/article/b4c6a06dddf248b4b95c7df5bc72b98a
Autor:
Takafumi Furuyama, Takafumi Shigeyama, Munenori Ono, Sachiko Yamaki, Kohta I Kobayasi, Nobuo Kato, Ryo Yamamoto
Publikováno v:
PLoS ONE, Vol 17, Iss 8, p e0272402 (2022)
Behaviors and vocalizations associated with aggression are essential for animals to survive, reproduce, and organize social hierarchy. Mongolian gerbils (Meriones unguiculatus) are highly aggressive and frequently emit calls. We took advantage of the
Externí odkaz:
https://doaj.org/article/4d1e6aa01a9141c28f6684c6b2174d49
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Intracellular amyloid β (Aβ) injection suppresses the large-conductance calcium-dependent potassium (BK) channel in cortical pyramidal cells from wild-type (WT) mice. In 3xTg Alzheimer’s disease (AD) model mice, intraneuronal Aβ is genetically p
Externí odkaz:
https://doaj.org/article/9be34387675d4c97969debc550a13404
Autor:
Wang Shuo, Haicong Li, Nishijo Muneko, Nishino Yoshikazu, Nobuo Kato, Yuji Kasamaki, Tadashi Ueda, Tsugiyasu Kanda
Publikováno v:
Journal of International Medical Research, Vol 48 (2020)
Objective Regulator of calcineurin 1 (RCAN1) controls plasticity of the nervous system and depressive conditions by regulating brain-derived neurotropic factor (BDNF) and plays a crucial role in neural and cardiac pathways. The apolipoprotein E gene
Externí odkaz:
https://doaj.org/article/30224b7c205f4533a83240c8f315763e
Publikováno v:
IBRO Reports, Vol 2, Iss C, Pp 81-86 (2017)
By using a 5-day forced swimming test (FS) that we previously developed, swim immobility was induced in 3xTg Alzheimer's model mice and wild-type (WT) mice. After the initial 5-day FS, the next and last swimming session was performed at a 4-week inte
Externí odkaz:
https://doaj.org/article/14d32bd798d74dfbbd6c405eb7929214
Autor:
Kenji Takagi, Tenko Hayashi, Shinjiro Sawada, Miku Okazaki, Sakiko Hori, Katsuya Ogata, Nobuo Kato, Yasuhito Ebara, Kunihiro Kaihatsu
Publikováno v:
Molecules, Vol 25, Iss 4, p 769 (2020)
During the treatment of viral or bacterial infections, it is important to evaluate any resistance to the therapeutic agents used. An amino acid substitution arising from a single base mutation in a particular gene often causes drug resistance in path
Externí odkaz:
https://doaj.org/article/8ed38034e15b4f0993e8707f55a99a1d