Zobrazeno 1 - 10 of 31 pro vyhledávání: '"Nobuki Hayashi"'
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Akademický článek
Serum levels of stearic and dihomo-γ-linolenic acids can be used to diagnose cervical cancer and cervical intraepithelial neoplasia
Autor: Yuki Katoh, Akiko Kubo, Nobuki Hayashi, Toshihiro Sugi, Kanoko Katoh, Seiichi Udagawa, Tadashi Ogawa, Takashi Iwata, Hiroshi Nishio, Masaki Sugawara, Shuichi Hirai, Kei Kawana
Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Despite widespread cervical cancer (CC) screening programs, low participation has led to high morbidity and mortality rates, especially in developing countries. Because early-stage CC often has no symptoms, a non-invasive and convenient diag
Externí odkaz: https://doaj.org/article/0f4a5207188b4c709e4af8153c0855cf
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3
Safety and efficacy of microwave endometrial ablation for patients with previous uterine surgery: a pilot study
Autor: Aki, Maebayashi, Nobuki, Hayashi, Saki, Kamata, Toshihiro, Sugi, Takahiro, Nakajima, Masaji, Nagaishi, Kei, Kawana
Publikováno v: Journal of Obstetrics and Gynaecology. 42:2164-2169
MEA (microwave endometrial ablation) is a treatment that can control hypermenorrhea. With the increase in the number of caesarean sections and myomectomies, an increasing number of patients with MEA have undergone previous incision of the uterine myo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6222cf46fd4348ff92cedcc398a5339
https://doi.org/10.1080/01443615.2022.2035330
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Abstract 4420: Small-molecule inhibition of Wee1 kinase by AZD1775 selectively sensitizes human papilloma virus (HPV)-associated cervical cancer to DNA-damaging therapies
Autor: Osamu Kobayashi, Yuji Ikeda, Yuki Okuma, Nobuki Hayashi, Takahiro Nakajima, Mikiko Asai-Sato, Kei Kawana
Publikováno v: Cancer Research. 79:4420-4420
Objective: Wee1 regulate G2-M checkpoint of cell-cycle Inhibition of Wee1 promotes cell mitosis without DNA repair in cases with TP53 deficiency Since human papillomavirus (HPV) E6 involves the inactivation of p53, we aimed to evaluate effects of Wee
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::006b2e425b65d7dff0d009af9de6cb49
https://doi.org/10.1158/1538-7445.am2019-4420
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Contribution of IL-18 to eosinophilic airway inflammation induced by immunization and challenge with Staphylococcus aureus proteins
Autor: Toshihiro Nakashima, Kiyoshi Matsui, Kazuhisa Sugimura, Hiroko Tsutsui, Kenji Nakanishi, Mai Kuroda-Morimoto, Yasutomo Imai, Shizue Yumikura-Futatsugi, Masakiyo Nakahira, Michiko Imamura, Hidehisa Tanaka, Nobuki Hayashi, Koubun Yasuda, Hajime Sano
Publikováno v: International Immunology. 22:561-570
We previously reported that intranasal challenge with ovalbumin (OVA) plus IL-18 induces airway hyperresponsiveness (AHR) and eosinophilic airway inflammation in mice with OVA-specific T(h)1 cells. These two conditions can be prevented by neutralizin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8220af09f89f2e8c48e4561cb6ba86f0
https://doi.org/10.1093/intimm/dxq040
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8
Freshly isolated Langerhans cells negatively regulate naïve T cell activation in response to peptide antigen through cell-to-cell contact
Autor: Yasutomo Imai, Koubun Yasuda, Nobuki Hayashi, Kenji Nakanishi, Hitoshi Mizutani, Hiroko Tsutsui
Publikováno v: Journal of Dermatological Science. 51:19-29
Summary Background Epidermal Langerhans cells (LCs) have been believed to function as professional antigen-presenting cells (APCs). However, LC-ablated mice reportedly suffer from severer contact hypersensitivity (CHS) upon cutaneous challenge with h
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c51026c93f81acffefc1cfd5a5490fa8
https://doi.org/10.1016/j.jdermsci.2008.01.005
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Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune system
Autor: Tomohiro Yoshimoto, Mai Morimoto, Nobuki Hayashi, Tomoaki Hoshino, Yuichi Kondo, Jiro Fujimoto, Kenji Nakanishi, Koubun Yasuda, Shizue Futatsugi-Yumikura
Publikováno v: International Immunology. 20:791-800
Systemic administration of IL-18 induces polyclonal IgE responses by causing NKT cells to express CD40 ligand and to produce IL-4. Administration of IL-33 also induces IgE response, although the mechanism underlying IgE response is unclear. Here, we
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::521c8a1f454e212477c1a96f385c9744
https://doi.org/10.1093/intimm/dxn037
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IL-18 together with anti-CD3 antibody induces human Th1 cells to produce Th1- and Th2-cytokines and IL-8
Autor: Toshikazu Hada, Hitomi Hata, Kenji Nakanishi, Tomohiro Yoshimoto, Nobuki Hayashi
Publikováno v: International Immunology. 16:1733-1739
Although IL-18 was initially regarded as a factor that enhances IFN-gamma production from Th1 cells, later studies revealed its potential to induce Th2 cytokine production from T cells, NK cells and basophils/mast cells. Very recently, we demonstrate
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c94c60726dc41c06b7706b97dfa0b001
https://doi.org/10.1093/intimm/dxh174
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