Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Nobuji Yoshikawa"'
Autor:
Guifeng Wang, Keiichi Hiramoto, Ning Ma, Shiho Ohnishi, Akihiro Morita, Yifei Xu, Nobuji Yoshikawa, Yasuo Chinzei, Mariko Murata, Shosuke Kawanishi
Publikováno v:
PLoS ONE, Vol 19, Iss 8, p e0307038 (2024)
We previously demonstrated that glycyrrhizin (GL) suppressed inflammation and carcinogenesis in an azoxymethane (AOM)/dextran sodium sulfate (DSS)-induced murine model of colorectal cancer (CC). In this study, we found an accumulation of regulatory T
Externí odkaz:
https://doaj.org/article/067a3af4972d4ae096ca0b1193171718
Autor:
Akihiro Morita, Yuta Omoya, Rie Ito, Yuya Ishibashi, Keiichi Hiramoto, Shiho Ohnishi, Nobuji Yoshikawa, Shosuke Kawanishi
Publikováno v:
Biochemistry and Biophysics Reports, Vol 28, Iss , Pp 101181- (2021)
The acute liver disease is involved in aberrant release of high-mobility group box 1 (HMGB1). Glycyrrhizin (GL), a traditional Chinese medicine for liver disease, binds to HMGB1, thereby inhibits tissue injury. However the mode of action of GL for ch
Externí odkaz:
https://doaj.org/article/925061da8e2a4c22b705612e946e2871
Autor:
Yasuaki Kabe, Ikko Koike, Tatsuya Yamamoto, Miwa Hirai, Ayaka Kanai, Ryogo Furuhata, Hitoshi Tsugawa, Erisa Harada, Kenji Sugase, Kazue Hanadate, Nobuji Yoshikawa, Hiroaki Hayashi, Masanori Noda, Susumu Uchiyama, Hiroki Yamazaki, Hirotoshi Tanaka, Takuya Kobayashi, Hiroshi Handa, Makoto Suematsu
Publikováno v:
Cancers, Vol 13, Iss 13, p 3265 (2021)
Progesterone receptor membrane component 1 (PGRMC1) is highly expressed in various cancer cells and contributes to tumor progression. We have previously shown that PGRMC1 forms a unique heme-stacking functional dimer to enhance EGF receptor (EGFR) ac
Externí odkaz:
https://doaj.org/article/654006beb9b7426eb8bcf719a12e0160
Autor:
Guifeng Wang, Keiichi Hiramoto, Ning Ma, Nobuji Yoshikawa, Shiho Ohnishi, Mariko Murata, Shosuke Kawanishi
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5, p 2609 (2021)
Glycyrrhizin (GL), an important active ingredient of licorice root, which weakens the proinflammatory effects of high-mobility group box 1 (HMGB1) by blocking HMGB1 signaling. In this study, we investigated whether GL could suppress inflammation and
Externí odkaz:
https://doaj.org/article/dd4c78b28dea482c8fe8fb84405157d5
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 2, p 506 (2020)
Hypoxic cellular proliferation is a common feature of tumor cells and is associated with tumor progression. Therefore, the inhibition of hypoxic cellular proliferation is expected to regulate malignancy processes. Licochalcone A (LicA) is known to sh
Externí odkaz:
https://doaj.org/article/05053fb9ebe9494f9636be9d490f681e
Autor:
Shosuke Kawanishi, Keiichi Hiramoto, Nobuji Yoshikawa, Kenji Goto, Yurika Yamate, Shiho Ohnishi, Akihiro Morita
Publikováno v:
Journal of Clinical Biochemistry and Nutrition
Metastasis, which accounts for the majority of all cancer-related deaths, occurs through several steps, namely, local invasion, intravasation, transport, extravasation, and colonization. Glycyrrhizin has been reported to inhibit pulmonary metastasis
Publikováno v:
International Journal of Molecular Sciences
Hypoxic cellular proliferation is a common feature of tumor cells and is associated with tumor progression. Therefore, the inhibition of hypoxic cellular proliferation is expected to regulate malignancy processes. Licochalcone A (LicA) is known to sh
Autor:
Inoyat Fattokhov, Madibron Saidov, Shinya Tamura, Isao Fujii, Ren Chiba, Nobuji Yoshikawa, Hiroaki Hayashi
Publikováno v:
Biological & Pharmaceutical Bulletin. 39:1781-1786
The characteristics of 2 Glycyrrhiza plants, G. glabra and G. bucharica (=Meristotropis bucharica), were investigated in Tajikistan. The glycyrrhizin content in the underground parts of G. glabra varied from 2.56 to 9.29% of the dry weight, and the c
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 2, p 506 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 2
International Journal of Molecular Sciences
Volume 21
Issue 2
Hypoxic cellular proliferation is a common feature of tumor cells and is associated with tumor progression. Therefore, the inhibition of hypoxic cellular proliferation is expected to regulate malignancy processes. Licochalcone A (LicA) is known to sh
Publikováno v:
Journal of Oleo Science. 63:1309-1322
Glycyrrhizic acid diethyl ester (GZ-DE) was developed as a prodrug of glycyrrhizic acid (GZ), a hepatitis therapeutic drug. We fortuitously found that GZ-DE gels with glycerin selectively while searching for a safe solvent with which to dissolve GZ-D