Výsledky vyhledávání - "Nobuhito Matsunaga"

Akademický článek

FKB327, an adalimumab biosimilar, versus the reference product: results of a randomized, Phase III, double-blind study, and its open-label extension

Autor: Mark C. Genovese, Josephine Glover, Maria Greenwald, Wieslawa Porawska, Elias Chalouhi El Khouri, Eva Dokoupilova, Juan Ignacio Vargas, Mykola Stanislavchuk, Herbert Kellner, Elena Baranova, Nobuhito Matsunaga, Rieke Alten

Publikováno v: Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-12 (2019)

Abstract Objective To compare the efficacy, serum drug concentrations, immunogenicity, and safety of FKB327 with the adalimumab reference product (RP) in combination with methotrexate in patients with moderate-to-severe, active rheumatoid arthritis (

Externí odkaz: https://doaj.org/article/1252aed2b70243f88faf1f3693138e6a

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MOESM3 of FKB327, an adalimumab biosimilar, versus the reference product: results of a randomized, Phase III, double-blind study, and its open-label extension

Autor: Genovese, Mark, Glover, Josephine, Greenwald, Maria, Wieslawa Porawska, Khouri, Elias, Dokoupilova, Eva, Vargas, Juan, Stanislavchuk, Mykola, Kellner, Herbert, Baranova, Elena, Nobuhito Matsunaga, Alten, Rieke

Additional file 3: Table S1. Baseline patient demographics and disease characteristics by treatment sequence in Period II.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c5c8b48050823c06677827bf0faa39a

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An experimental design for judging synergism on consideration to endocrine disruptor animal experiments

Autor: Isao Yoshimura, Chikuma Hamada, Jun Kanno, Nobuhito Matsunaga

Publikováno v: Environmetrics. 20:1-13

This paper investigates an appropriate statistical design for an animal experiment to evaluate synergism of two test chemicals. It assumes a certain number of animals are divided into groups, each of which is treated with a combination of dose levels

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a85dc8416c63a5adb3b07e81a17c865e
https://doi.org/10.1002/env.898

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A statistical method for judging synergism: application to an endocrine disruptor animal experiment

Autor: Nobuhito Matsunaga, Isao Yoshimura, Jun Kanno

Publikováno v: Environmetrics. 14:213-222

This article proposes a statistical method for judging whether or not the combined action of chemicals is synergistic, being focused on the case in which two or more endocrine disruptors are made to act simultaneously. After defining synergism, the s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fe770404159fbfa9b82d2f79538aefd2
https://doi.org/10.1002/env.578

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