Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Nobuhisa Fukuda"'
Autor:
Rieko Kawamura, Tetsuya Nakasatomi, Birei Furuta, Teruhide Yamaguchi, Emi Ikebe, Keiko Miyakawa, Haruka Momose, Yutaka Maeda, Sahoko Matsuoka, Isao Hamaguchi, Nobuhisa Fukuda, Saeko Mizusawa, Yuko Gotanda, Kenichi Togashi, Eriko Uchida, Miyuki Tsukahara, Shigeru Kusagawa, Masaki Ochiai, Takashi Hasegawa, Yoshiaki Okada
Publikováno v:
Japanese Journal of Transfusion and Cell Therapy. 64:502-509
Autor:
Matsuda Koichi, Masato Iwata, Kuniko Suzuki, Katsuya Fujita, Ryo Nakayama, Nobuhisa Fukuda, Seiji Hori, Futoshi Hasegawa, Kenji Kawane, Masaya Mori, Seiji Katayama, Tetsuro Nariai, Hiroshi Kato
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 354:2-9
Mineralocorticoid receptor (MR) antagonists, such as spironolactone (SPI) and eplerenone (EPL), are useful for treating hypertension and heart failure. However, these two agents have the serious side effect of hyperkalemia. We hypothesized that addin
Publikováno v:
Organic Letters. 9:259-262
Catalytic asymmetric synthesis of Tamiflu, an important antiinfluenza drug, was achieved. After the catalytic enantioselective desymmetrization of meso-aziridine 3 with TMSN3, using a Y catalyst (1 mol %) derived from ligand 2, an allylic oxygen func
Publikováno v:
The Journal of Organic Chemistry. 71:1220-1225
Total synthesis of (+)-lactacystin, a potent and selective proteasome inhibitor, was accomplished using a catalytic enantioselective Strecker reaction of a ketoimine as the initial key step. An enone-derived N-phosphinoyl ketoimine 7 was selected as
Autor:
Toshiaki Tsujino, Yasuyuki Kita, Hiromichi Fujioka, Nobuhisa Fukuda, Kiyosei Iio, Tadaatsu Naka, Emi Akiyama, Kazuhiro Higuchi, Ken-ichi Kawaguchi, Yoshifumi Takeda, Shuji Akai
Publikováno v:
Chemistry - A European Journal. 11:6286-6297
The asymmetric total synthesis of the potent antitumor antibiotic fredericamycin A ((S)-1) was achieved by the intramolecular [4+2] cycloaddition of the silylene-protected styrene derivative (S)-7 followed by the aromatic Pummerer-type reaction of th
Autor:
Yoshihiro Fukuda, Hiromasa Koizuka, Takeshi Kusaka, Manabu Hashimoto, Masumi Okuda, Junichiro Kotake, Noriyasu Yamamoto, Kohei Maekawa, Nobuhisa Fukuda
Publikováno v:
Journal of Gastroenterology and Hepatology. 27:100-102
Background and Aim: Ecabet sodium is reported to have a bactericidal effect on Helicobacter pylori and inhibit urease activity in vitro. Methods: Seven male volunteers (mean age, 51.3 years; range, 45–55 years) with H. pylori infection were medicat
Autor:
Nobuhisa Fukuda, Nobukazu Ohkubo, Daizo Kawasaki, Masaaki Kato, Tohru Masuyama, Masashi Fukunaga, Kenichi Fujii
Publikováno v:
Angiology. 66(3)
We evaluated the feasibility, safety, and mid-term outcomes of renal artery stenting using carbon dioxide (CO2) digital subtraction angiography and intravascular ultrasound (IVUS) for patients with renal insufficiency and significant atherosclerotic
Autor:
Shuji Akai, Yasuyuki Kita, Nobuhisa Fukuda, Kiyosei Iio, Kazuhiro Higuchi, Toshiaki Tsujino, Tadaatsu Naka, Yoshifumi Takeda, Ken-ichi Kawaguchi
Publikováno v:
Organic Letters. 3:4015-4018
[reaction: see text] An intramolecular enantiodivergent synthesis of both enantiomers of the ABCDE-ring analogue 22 of fredericamycin A is reported. Key steps involve an intramolecular [4 + 2] cycloaddition of 17 and an aromatic Pummerer-type reactio
Autor:
Nobuhisa Fukuda, Ryuichi Okunaka, Kiyosei Iio, Shuji Akai, Yasuyuki Kita, Toshiaki Tsujino, Kazuhiro Higuchi, Hiroshi Ueno, Yoshifumi Takeda, Hiromichi Fujioka, Ken-ichi Kawaguchi
Publikováno v:
Chemistry. 6:3897-3905
A linear approach to the total synthesis of racemic fredericamycin A (1) through the oxidative intramolecular [4 + 2] cycloaddition of a (phenylthio)acetylene-cobalt complex is described, which is applicable for the asymmetric total synthesis of natu
Publikováno v:
Nihon rinsho. Japanese journal of clinical medicine. 70