Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Nobuhiro Sasai"'
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68478 (2013)
Cellular senescence is post-mitotic or oncogene-induced events combined with nuclear remodeling. MCAF1 (also known as hAM or ATF7IP), a transcriptional cofactor that is overexpressed in various cancers, functions in gene activation or repression, dep
Externí odkaz:
https://doaj.org/article/e10ddaf373b340f3b7e69f74412a0c87
The human proteins MBD5 and MBD6 associate with heterochromatin but they do not bind methylated DNA.
Autor:
Sophie Laget, Michael Joulie, Florent Le Masson, Nobuhiro Sasai, Elisabeth Christians, Sriharsa Pradhan, Richard J Roberts, Pierre-Antoine Defossez
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e11982 (2010)
BackgroundMBD5 and MBD6 are two uncharacterized mammalian proteins that contain a putative Methyl-Binding Domain (MBD). In the proteins MBD1, MBD2, MBD4, and MeCP2, this domain allows the specific recognition of DNA containing methylated cytosine; as
Externí odkaz:
https://doaj.org/article/23e7c5a57b244ae4b24a4b6fb68b9666
Publikováno v:
Briefings in Functional Genomics. 11:251-264
Methylated DNA can be specifically recognized by a set of proteins called methyl-CpG-binding proteins (MBPs), which belong to three different structural families in mammals: the MBD family, the Kaiso and Kaiso-like proteins and the SRA domain protein
Autor:
Daisuke Yamada, M L Schmitz, Philippe Ravassard, B Jammart, Nobuhiro Sasai, M Caly, Xavier Sastre-Garau, Guillaume J. Filion, Jacques Mallet, V Devignot, Roberto Pérez-Torrado, Pierre-Antoine Defossez
Publikováno v:
Oncogene. 28:2535-2544
HIPK2 is a eukaryotic Serine-Threonine kinase that controls cellular proliferation and survival in response to exogenous signals. Here, we show that the human transcription factor ZBTB4 is a new target of HIPK2. The two proteins interact in vitro, co
Publikováno v:
The International Journal of Developmental Biology. 53:323-334
DNA methylation is an epigenetically inherited chemical modification that is associated with transcriptional silencing and is essential for mammalian development. The DNA methylation signal is read out by methyl-CpG binding proteins (MBPs) that speci
Publikováno v:
Heredity. 86:206-212
In order to study P element dynamics in natural populations of Drosophila melanogaster, 126 isofemale lines were examined from seven of the southernmost islands of Japan (the Sakishima Islands) and from Taiwan. Gonadal dysgenesis (GD) tests showed la
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 7, p e68478 (2013)
PLoS ONE, Vol 8, Iss 7, p e68478 (2013)
Cellular senescence is post-mitotic or oncogene-induced events combined with nuclear remodeling. MCAF1 (also known as hAM or ATF7IP), a transcriptional cofactor that is overexpressed in various cancers, functions in gene activation or repression, dep
Publikováno v:
Nihon rinsho. Japanese journal of clinical medicine. 70
Publikováno v:
Nucleic Acids Research
DNA methylation is an essential epigenetic mark. Three classes of mammalian proteins recognize methylated DNA: MBD proteins, SRA proteins and the zinc-finger proteins Kaiso, ZBTB4 and ZBTB38. The last three proteins can bind either methylated DNA or
Publikováno v:
The FEBS journal. 274(23)
Jumonji (Jmj) is a transcriptional repressor that plays important roles in the suppression of cell proliferation and development of various tissues in the mouse. To further clarify the roles of Jmj during development and gain insight into mechanisms