Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Nobuhiro, Noro"'
Publikováno v:
Biology, Vol 10, Iss 11, p 1212 (2021)
(1) Background: The control of angiogenesis is essential in disease treatment. We investigated angiogenesis-promoting or -suppressing factors and their molecular mechanisms. (2) Methods: Angiogenesis from HUVECs was quantitatively analyzed using the
Externí odkaz:
https://doaj.org/article/3de7113a8937453692d92c07b45fe146
Publikováno v:
Biology
Biology; Volume 10; Issue 11; Pages: 1212
Biology, Vol 10, Iss 1212, p 1212 (2021)
Biology; Volume 10; Issue 11; Pages: 1212
Biology, Vol 10, Iss 1212, p 1212 (2021)
Simple Summary The control of angiogenesis is essential in disease treatment or regenerative medicine. We conducted a clinical study of dedifferentiated fat (DFAT) cells, a kind of mesenchymal stem cells, by applying cell transplantation therapy to i
Autor:
Lihua Shan, Shinobu Noritake, Masatoshi Fujiwara, Chikako Yoshida-Noro, Nobuhiro Noro, Satoshi Asano, Keizo Yamashita, Takao Kawakami
Publikováno v:
Inflammation. 35:702-712
Airway epithelium is a key component for airway integrity. Previously, we found that expression of the Sec14l3 gene that encodes a 45-kDa secretory protein is inversely associated with the progression of experimentally induced airway inflammation and
Autor:
Keizo Yamashita, Takato Noumi, Hiroshi Sootome, Nobuhiro Noro, Mikiya Suda, Alastair J. King, Megumi Shibahara, Tsuyoshi Ishii
Publikováno v:
Analytical and Bioanalytical Chemistry. 390:343-348
No universal approach has been reported for specific monitoring of the catalytic activity of a wide range of kinases in cells. The present study describes an original platform for detecting the autonomous activity of serine/threonine kinases in cells
Autor:
Victoria B. Knick, Tona M. Gilmer, Daniel F. Hassler, Masaaki Furuta, Randy T. McConnell, Glenn M. Spehar, Nobuhiro Noro, Kyle A. Emmitte, Robert A. Mook, Timothy J. Lansing, Mui Cheung, Derek R. Duckett
Publikováno v:
Molecular Cancer Therapeutics. 6:450-459
Polo-like kinase 1 (PLK1) plays key roles in the regulation of mitotic progression, including mitotic entry, spindle formation, chromosome segregation, and cytokinesis. PLK1 expression and activity are strongly linked to proliferating cells. Many stu
Publikováno v:
Gene. 283:299-309
The microtubules of the mammalian nervous system are stabilised by several microtubule-associated proteins (MAPs), including the tau and MAP-2 protein families. The most prominent feature of mammalian tau and MAP-2 proteins is a common and highly hom
Publikováno v:
Development, Growth and Differentiation. 40:177-188
The present study used a molecular approach toward understanding the mechanism of hormone- and region-dependent remodeling of the small intestine during metamorphosis of Xenopus laevis. A protein spot was noticed on a two-dimensional polyacrylamide g
Autor:
Katsutoshi Yoshizato, Koyomi Miyazaki, Jean Vacelet, Jean-Yves Exposito, Robert Garrone, Nicole Boury-Esnault, Nicolas Boute, Nobuhiro Noro
Publikováno v:
Biology of the Cell. 88:37-44
Basement membrane structures, or their main component, type IV collagen, have been detected in all multicellular animal species, except sponges. We cancel this exception by the demonstration of type IV collagenous sequences in a new marine sponge spe
Autor:
Tsuyoshi, Ish, Hiroshi, Sootome, Alastair J, King, Mikiya, Suda, Nobuhiro, Noro, Keizo, Yamashita, Takato, Noumi, Tsuyoshi, Ishii
Publikováno v:
Journal of biomolecular screening. 12(6)
Checkpoint kinase 1 (Chk1), a serine/threonine kinase, plays an important role in DNA damage checkpoint control and is an attractive target for cancer treatment. To develop a Chk1-specific cell-based assay, stable clones were established in which Chk
Autor:
Tsuyoshi, Ish, Hiroshi, Sootome, Yukiko, Yagi, Keizo, Yamashita, Takato, Noumi, Nobuhiro, Noro, Tsuyoshi, Ishii
Publikováno v:
Journal of biomolecular screening. 12(6)
The Ras/Raf signaling pathway has been recognized as an important process in cancer biology. Recently, activating mutations in the BRAF gene were reported to be present in approximately 66% of malignant melanomas as well as other malignancies such as