Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Nobuhiro, Iwakura"'
Autor:
Nobuhiro Iwakura, Takeshi Yokoyama, Fabio Quaglia, Kaoru Mitsuoka, Kazuhiro Mio, Hideki Shigematsu, Mikako Shirouzu, Akira Kaji, Hideko Kaji
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177972 (2017)
A model Post-Termination Complex (PoTC) used for the discovery of Ribosome Recycling Factor (RRF) was purified and characterized by cryo-electron microscopic analysis and biochemical methods. We established that the model PoTC has mostly one tRNA, at
Externí odkaz:
https://doaj.org/article/99d1747f4cd9493ca742c971a208bc8a
Autor:
Hirokazu Isobe, Yasuhisa Iwao, Tatsuo Yamamoto, Akihito Nishiyama, Wei-Chun Hung, Tomomi Takano, Ikue Taneike, Saori Nakagawa, Soshi Dohmae, Nobuhiro Iwakura
Publikováno v:
FEMS Immunology & Medical Microbiology. 66:343-352
The mechanisms for the cytotoxicity of staphylococcal Panton-Valentine leukocidin (PVL), a pore-forming toxin consisting of LukS-PV and LukF-PV, in human immune cells are still unclear. Because LukS-PV binds to ganglioside GM1, a constituent of deter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f2efd8826d450e5de9a27337749fc9e
https://doi.org/10.1111/j.1574-695x.2012.01027.x
https://doi.org/10.1111/j.1574-695x.2012.01027.x
Autor:
Nobuhiro Iwakura, Hideko Kaji, Tanvir R. Shaikh, Rajendra K. Agrawal, Akira Kaji, Takeshi Yokoyama
Publikováno v:
The EMBO Journal. 31:1836-1846
The ribosome-recycling factor (RRF) and elongation factor-G (EF-G) disassemble the 70S post-termination complex (PoTC) into mRNA, tRNA, and two ribosomal subunits. We have determined cryo-electron microscopic structures of the PoTC·RRF complex, with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2fc32298b658e2d70f8311491ad92aa4
https://doi.org/10.1038/emboj.2012.22
https://doi.org/10.1038/emboj.2012.22
Publikováno v:
The FASEB Journal. 29
Although spermine (Spm) is not present in E. coli, 100 µM Spm inhibited the disassembly of the model PoTC 100%. On the other hand, in vitro incorporation of amino acids programmed by synthetic mRNA...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16acf0a0b269cfe12305c419db467a3f
https://doi.org/10.1096/fasebj.29.1_supplement.892.1
https://doi.org/10.1096/fasebj.29.1_supplement.892.1
Autor:
Koji Kushiya, Saori Nakagawa, Ikue Taneike, Nobuhiro Iwakura, Tatsuo Yamamoto, Hiroki Tsukada, Fumitake Gejyo, Ken'ichi Imanishi, Takehiko Uchiyama
Publikováno v:
Journal of Infection and Chemotherapy. 11:192-195
Staphylococcus aureus, including methicillin-resistant S. aureus (MRSA), produces superantigenictoxins, such as toxic shock syndrome toxin-1 (TSST-1). TSST-1 abnormally activates T cells to overproduce inflammatory cytokines (such as tumor necrosis f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2d92ad2a23d878aa00bc58eb59a5862
https://doi.org/10.1007/s10156-005-0389-8
https://doi.org/10.1007/s10156-005-0389-8
Autor:
Tatsuo Yamamoto, Koji Kushiya, Yukiko Tamura, Seiichi Kojio, Ikue Taneike, Saori Nakagawa, Fumio Gondaira, Nobuhiro Iwakura
Publikováno v:
Biochemical and Biophysical Research Communications. 310:1194-1199
Shiga toxin (Stx)-producing Escherichia coli (STEC) is associated with hemolytic uremic syndrome (HUS). High inflammatory cytokine [interleukin (IL)-6 and IL-8] levels and low anti-inflammatory cytokine (IL-10) levels are indicators of a high risk fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a97ca3eee18535b141a58d09828d8c51
https://doi.org/10.1016/j.bbrc.2003.09.145
https://doi.org/10.1016/j.bbrc.2003.09.145
Autor:
Hideko Kaji, Mikako Shirouzu, Kaoru Mitsuoka, Hideki Shigematsu, Fabio Quaglia, Nobuhiro Iwakura, Akira Kaji, Kazuhiro Mio, Takeshi Yokoyama
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177972 (2017)
PLoS ONE
PLoS ONE
A model Post-Termination Complex (PoTC) used for the discovery of Ribosome Recycling Factor (RRF) was purified and characterized by cryo-electron microscopic analysis and biochemical methods. We established that the model PoTC has mostly one tRNA, at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a013b2e5bc877a77c955e28c1ccc3c3a
https://doi.org/10.1371/journal.pone.0177972
https://doi.org/10.1371/journal.pone.0177972
Publikováno v:
The FASEB Journal. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b105b24c73a7762cd99223f94789d1e6
https://doi.org/10.1096/fasebj.27.1_supplement.986.1
https://doi.org/10.1096/fasebj.27.1_supplement.986.1
Autor:
Akira Kaji, Serafín Vivanco-Domínguez, Nobuhiro Iwakura, Hideko Kaji, Gabriel Guarneros, José Bueno-Martínez, Gloria León-Ávila
Publikováno v:
Journal of molecular biology. 417(5)
During translation, ribosomes stall on mRNA when the aminoacyl-tRNA to be read is not readily available. The stalled ribosomes are deleterious to the cell and should be rescued to maintain its viability. To investigate the contribution of some of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eff231a2da1df1959d2c8fa5a7416025
https://pubmed.ncbi.nlm.nih.gov/22326347
https://pubmed.ncbi.nlm.nih.gov/22326347
Autor:
Takeshi, Yokoyama, Tanvir R, Shaikh, Nobuhiro, Iwakura, Hideko, Kaji, Akira, Kaji, Rajendra K, Agrawal
Publikováno v:
The EMBO journal. 31(7)
The ribosome-recycling factor (RRF) and elongation factor-G (EF-G) disassemble the 70S post-termination complex (PoTC) into mRNA, tRNA, and two ribosomal subunits. We have determined cryo-electron microscopic structures of the PoTC·RRF complex, with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::00d0d638999a0f8dfe7bd0f333e1d977
https://pubmed.ncbi.nlm.nih.gov/22388519
https://pubmed.ncbi.nlm.nih.gov/22388519