Výsledky vyhledávání - "Nobuhiko Shibata"

Adrenal androgen dehydroepiandrosterone sulfate inhibits vascular remodeling following arterial injury

Autor: Masaaki, Nobuhiko Shibata, Nakaaki Ohsawa, Toshiaki Hanafusa, Tadashi Ishihara, Nobuyuki Negoro, Ryosuke Fukui, Douglas W. Losordo, Masaaki Hoshiga, Eiko Kohbayashi, Daisuke Furutama, Takahiro Nakakoji

Publikováno v: Atherosclerosis. 206:77-85

Recent epidemiologic studies have suggested that serum dehydroepiandrosterone sulfate (DHEAS) levels have a significant inverse correlation with the incidence of cardiovascular diseases. However, direct evidence for the association with DHEAS and vas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f671571a8ad01b1c134d99711b5d243d
https://doi.org/10.1016/j.atherosclerosis.2009.02.021

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Randomized, controlled trial of secondary prevention of coronary sclerosis in normocholesterolemic patients using pravastatin: two-year follow-up of the prevention of coronary sclerosis study

Autor: Minoru Iida, Motohiro Kirino, Tadao Itoh, Johan H. C. Reiber, Yumiko Nakagawa, Nobuhiko Shibata, Hisatoyo Hiraoka, Nobuhisa Awata, Shinichi Sato, Tomoko Kobayashi, Osamu Katoh, Tohru Kobayashi

Publikováno v: Current Therapeutic Research. 62:473-485

Background: Reducing serum total cholesterol (TC) levels using 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors in hypercholesterolemic patients has been shown to reduce the incidence of complications of coronary heart disease (CH

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b569e7db9ed56f73fde75c2dd3187efe
https://doi.org/10.1016/s0011-393x(01)80058-8

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Increased migration in late G1phase in cultured smooth muscle cells

Autor: Ryosuke Fukui, Nobuyuki Negoro, Nakaaki Ohsawa, Masahiro Amakawa, Nobuhiko Shibata, Masaaki Hoshiga, Masaaki, Minoru Seto, Teruo Ueno, Takahiro Nakakoji, Yasuharu Sasaki, Eiko Kohbayashi, Futoshi Nishiguchi, Tadashi Ishihara

Publikováno v: American Journal of Physiology-Cell Physiology. 279:C999-C1007

Migration and proliferation of smooth muscle cells (SMC) contribute to neointimal formation after arterial injury. However, the relation between migration and proliferation in these cells is obscure. To discriminate between migration and proliferatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90c1e260bb3f03a66a99529fe1d2a39d
https://doi.org/10.1152/ajpcell.2000.279.4.c999

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The Kinase Inhibitor Fasudil (HA-1077) Reduces Intimal Hyperplasia through Inhibiting Migration and Enhancing Cell Loss of Vascular Smooth Muscle Cells

Autor: Nobuyuki Negoro, Masaaki Hoshiga, Minoru Seto, Eiko Kohbayashi, Masaaki Ii, Ryosuke Fukui, Nobuhiko Shibata, Takahiro Nakakoji, Futoshi Nishiguchi, Yasuharu Sasaki, Tadashi Ishihara, Nakaaki Ohsawa

Publikováno v: Biochemical and Biophysical Research Communications. 262:211-215

Smooth muscle cell (SMC) migration plays an important role in restenosis after angioplasty. Myosin phosphorylation is necessary for cell migration. Fasudil is an inhibitor of protein kinases, including myosin light chain kinase and Rho associated kin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce2e4fe04d22551c78fe5ea5c0664045
https://doi.org/10.1006/bbrc.1999.1129

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Mice lacking smooth muscle calponin display increased bone formation that is associated with enhancement of bone morphogenetic protein responses

Autor: Shun'ichiro Taniguchi, Kenji Nakamura, Hisako Yamamura, Nobuhiko Shibata, Mizuo Sugimoto, Motoya Katsuki, Shigeki Mori, Katsuhito Takahashi, Kazuki Nakao, Hideki Yoshikawa, Kenji Miyado

Publikováno v: Genes to Cells. 3:685-695

Background Calponin is a calmodulin-and actin-binding protein expressed in smooth muscle. It promotes actin polymerization and inhibits actin-activated myosin ATPase activity. Despite the molecular and functional characterization of calponin in vitro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68593d4e32b8a52adb384cb2330edb32
https://doi.org/10.1046/j.1365-2443.1998.00214.x

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Molecular Cloning and Characterization of Human Non-Smooth Muscle Calponin

Autor: Nobuhiko Shibata, Michiko Takagi, Kinya Ohgami, Kazuhiko Tanaka, Katsuhito Takahashi, Tetsuo Sakamaki, Hiroaki Masuda

Publikováno v: Journal of Biochemistry. 120:415-424

cDNA clones encoding a calponin isoform with 309 amino acids have been isolated from human heart. The deduced amino acid polypeptide (M(r) 33,697) showed a neutral isoelectric point of 7.1. The mRNA, expressed in cultured smooth muscle cells as well

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c58257051060a462d8b23a0373cf7d6
https://doi.org/10.1093/oxfordjournals.jbchem.a021428

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The 5'-Flanking Region of the Human Smooth Muscle Cell Calponin Gene Contains a cis-Acting Domain for Interaction with a Methylated DNA-Binding Transcription Repressor

Autor: Akiko Miki, Kinya Ohgami, Nobuhiko Shibata, Tetsushi Tazunoki, Tsutomu Okada, Katsuhito Takahashi, Takeshi Miwa

Publikováno v: Journal of Biochemistry. 120:18-21

The human smooth muscle cell (SMC) calponin gene, which is composed of seven exons and six introns, spanning an approximately 11.2 kilobase (kb) genomic DNA, has been isolated and characterized by sequence analysis. As determined by primer extension

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::796e0e45d88d571c158388a847186b04
https://doi.org/10.1093/oxfordjournals.jbchem.a021382

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Coronary angioplasty of chronic total occlusions with bridging collateral vessels: immediate and follow-up outcome from a large single-center experience

Autor: Hitone Tateyama, Isao Kinoshita, Satoru Otsuji, Tohru Kobayashi, Nobuhiko Shibata, Nakaaki Ohsawa, Tadashi Ishihara, Jin Nariyama, Osamu Katoh

Publikováno v: Journal of the American College of Cardiology. 26:409-415

Objectives. The purpose of the present study was to assess the effect of bridging collateral vessels on the success of coronary angioplasty of chronic total occlusions in the context of state of the art technology and operator skill. Background. Coro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c3789e46ac688d78007c2547ecb4822
https://doi.org/10.1016/0735-1097(95)80015-9

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Neurosteroids in cerebrospinal fluid in neurologic disorders

Autor: Kenji Tone, Tetsuo Fujimoto, Saburo Sakoda, Yoshihito Shima, Tsutomu Azuma, Shigehiko Haeno, Nobuhiko Shibata, Tsuyoshi Matsubara

Publikováno v: Journal of the Neurological Sciences. 120:87-92

In order to investigate the role of "neurosteroids" in the central nervous system (CNS), cerebrospinal fluid (CSF) levels of dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) were determined by radioimmunoassay in 57 patients w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58b262ed149f9eba072cbb654cf4ac57
https://doi.org/10.1016/0022-510x(93)90030-3

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