Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Nobuhiko Kanazawa"'
Publikováno v:
Journal of applied toxicology : JATREFERENCES. 41(3)
The branched isomer mixture 4-nonylphenol (4-NP) has been used worldwide as a surfactant, and can have endocrine-disrupting effects on aquatic organisms. For instance, 4-NP induces the formation of testis-ova (i.e., testicular and ovarian tissue in t
Autor:
Mika Suzuki, Takumi Jiroumaru, Hiroko Kawasaki, Takashi Yasuda, Shinichi Noguchi, Hitomi Bunki, Hitoshi Onishi, Kouhei Nakata, Masae Ikeya, Nobuhiko Kanazawa, Takashi Uozaki, Ryou Fujitani
Publikováno v:
Rigakuryoho Kagaku. 33:917-920
Publikováno v:
Journal of applied toxicology : JATREFERENCES. 40(6)
Bisphenol A (BPA), a very important raw material in the plastics industry, is an endocrine-disrupting chemical in teleost fish. Although BPA induces testis-ova and sex reversal in teleost fish species, the molecular mechanism remains unclear. We eval
Autor:
Daichi Tanaka, Nobuhiko Kanazawa, Tadashi Suga, Takatoshi Higuchi, Michio Wachi, Ryo Tsuchikane, Yuto Miyake, Tadao Isaka, Jun Misaki
Publikováno v:
Journal of Physical Therapy Science
[Purpose] Recently, we demonstrated that the thicknesses of trunk muscles measured using ultrasonography were correlated strongly with the cross-sectional areas measured using magnetic resonance imaging in untrained subjects. To further explore the a
Autor:
Nobuyuki Enomoto, Shinya Maekawa, Mamoru Watanabe, Masayuki Kurosaki, Yoshie Takeda, Yasuhiro Itsui, Naoya Sakamoto, Sei Kakinuma, Yuko Sekine, Yoko Tanabe, Tomoyuki Koyama, Nobuhiko Kanazawa, Mina Nakagawa
Publikováno v:
Journal of Viral Hepatitis. 13:690-700
Type-I interferons (IFNs) and the interferon-stimulated genes (ISGs) play a major role in antivirus responses against hepatitis C virus (HCV) infection. In this study, we studied expression profiles of ISGs in cells supporting subgenomic HCV replicat
Negative regulation of intracellular hepatitis C virus replication by interferon regulatory factor 3
Autor:
Yoko Tanabe, Mamoru Watanabe, Tsuyoshi Yamashiro, Naoya Sakamoto, Yasuhiro Itsui, Nobuhiko Kanazawa, Yoshie Takeda, Mina Nakagawa, Nobuyuki Enomoto, Shinya Maekawa, Hiroshi Sakugawa, Masayuki Kurosaki, Tomoyuki Koyama, Cheng-Hsin Chen
Publikováno v:
Journal of Gastroenterology. 41:750-757
Interferon regulatory factor (IRF)-3 plays an important role in initiating cellular interferon-stimulated gene-mediated antiviral responses. In the present study, we evaluated the effects of IRF-3 expression and activation on intracellular hepatitis
Autor:
T. Kohashi, Hideki Watanabe, Naoya Sakamoto, Mina Nakagawa, Mamoru Watanabe, Nobuhiko Kanazawa, Masayuki Kurosaki, Sei Kakinuma, Nobuyuki Enomoto, Shinya Maekawa, Tsuyoshi Yamashiro, Yasuhiro Itsui, Tomoyuki Koyama, Cheng-Hsin Chen, Yoko Tanabe
Publikováno v:
Journal of Viral Hepatitis. 13:582-590
The number of amino acid substitutions in the interferon sensitivity-determining region (ISDR) in the nonstructural 5A (NS5A) gene of hepatitis C virus (HCV) is closely associated with the interferon (IFN) response and viral load. Several HCV replico
Autor:
Chifumi Sato, Cheng-Hsin Chen, Nobuhiko Kanazawa, Yoko Tanabe, Nobuyuki Enomoto, Shinya Maekawa, Mamoru Watanabe, Hisayoshi Watanabe, E Ueda, Mina Nakagawa, T. Kohashi, Naoya Sakamoto, Masayuki Kurosaki, Tsuyoshi Yamashiro
Publikováno v:
Journal of Viral Hepatitis. 11:394-403
Hepatitis C virus (HCV) subgenomic replicon has been reported to replicate efficiently and continuously in human hepatoma Huh-7 cells. To extend the previous results to other isolated HCV clones, we constructed another HCV replicon from HC-J4, one of
Autor:
Yoshiro Himeno, Masakatsu Uchihara, Kaoru Sakurai, Jun Itakura, Osamu Noguchi, Kazuhiro Taki, Namiki Izumi, Kaoru Tsuchiya, Nobuhiko Kanazawa, Nobuyuki Enomoto, Yasuhiro Asahina, Shozo Miyake, Yasuhiro Kawachi, Hidetoshi Shiotsu, Mamoru Watanabe, Kosei Hamano, Takahiro Sakai, Naoto Miyakawa
Publikováno v:
Hepatology Research. 24:80-88
A 31-year-old Japanese male was admitted to our hospital for investigation of an asymptomatic nodular lesion of the liver detected by abdominal ultrasonography (US) during a routine medical examination. Computed tomography (CT) revealed a single, hyp
Autor:
Osamu Noguchi, Namiki Izumi, Kosei Hamano, Jun Itakura, Shozo Miyake, Yasuhiro Asahina, Masakatsu Uchihara, Takahiro Sakai, Sukenobu Kawamura, Nobuhiko Kanazawa, Kaoru Tsuchiya
Publikováno v:
Nihon Naika Gakkai Zasshi. 91:2192-2195
症例は39歳,男性. B型慢性肝炎の急性増悪のため近医入院.肝不全徴候を認めlamivudine 100mg内服を開始した.投与開始後速やかに肝逸脱酵素は改善し, HBV DNAは感度以下となった. lamivudine投与10