Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Nobuhiko Imahashi"'
Autor:
Li Li, Michael Green, Fang Wang, Ye Li, Jennifer Wargo, Marina Konopleva, Elizabeth J Shpall, Rafet Basar, May Daher, Ana Karen Nunez Cortes, Hila Shaim, Natalia Baran, Ken Chen, Luis Muniz-Feliciano, Nobuhiko Imahashi, Yuefan Huang, Pinaki Prosad Banerjee, Junjun Lu, Nadima Uprety, Emily Ensley, Tamara J Laskowski, Judy S Moyes, Mayela Mendt, Lucila N Kerbauy, Mayra Shanley, Francesca Lorraine Wei Inng Lim, Katayoun Rezvani
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 12 (2022)
Background B cells play a pivotal role in regulating the immune response. The induction of B cell-mediated immunosuppressive function requires B cell activating signals. However, the mechanisms by which activated B cells mediate T-cell suppression ar
Externí odkaz:
https://doaj.org/article/d3edf7d013de4e0baf660853daac9cb7
A novel immature natural killer cell subpopulation predicts relapse after cord blood transplantation
Autor:
Li Li, Han Chen, David Marin, Yuanxin Xi, Qi Miao, Jiangxing Lv, Pinaki Prosad Banerjee, Hila Shaim, May Daher, Rafet Basar, Nobuhiko Imahashi, Juan Jimenez, Bingqian Hu, Rohtesh S. Mehta, Lucila Nassif Kerbauy, Mecit Kaplan, Mayela Mendt, Gonca Ozcan, Elif Gokdemir, Mayra Hernandez Sanabria, Ye Li, Ken Chen, Jing Wang, Luis Muniz-Feliciano, Wei-Li Zhao, Richard E. Champlin, Elizabeth J. Shpall, Katayoun Rezvani
Publikováno v:
Blood Advances, Vol 3, Iss 23, Pp 4117-4130 (2019)
Abstract: Natural killer (NK) cells are highly heterogeneous, with vast phenotypic and functional diversity at the single-cell level. They are involved in the innate immune response against malignant and virus-infected cells. To understand the effect
Externí odkaz:
https://doaj.org/article/2a7a56d202f04a7b9d59cab57a91513d
Autor:
Nobuhiko Imahashi, Mikiko Arakawa, Akari Iwakoshi, Mikiko Mori, Hirokazu Nagai, Hiroatsu Iida
Publikováno v:
eJHaem, Vol 3, Iss 2, Pp 569-570 (2022)
Externí odkaz:
https://doaj.org/article/3df7136432664559aee2ef839182ef75
Autor:
Hila Shaim, Zeev Estrov, David Harris, Mayra Hernandez Sanabria, Zhiming Liu, Peter Ruvolo, Phillip A. Thompson, Alessandra Ferrajoli, May Daher, Jan Burger, Muharrem Muftuoglu, Nobuhiko Imahashi, Li Li, Enli Liu, Abdullah Saleh Alsuliman, Rafet Basar, Lucila Nassif Kerbauy, Catherine Sobieski, Elif Gokdemir, Kayo Kondo, William Wierda, Michael Keating, Elizabeth J. Shpall, Katayoun Rezvani
Publikováno v:
Frontiers in Immunology, Vol 8 (2018)
Chronic lymphocytic leukemia (CLL) cells possess regulatory functions comparable to those of normal B10 cells, a regulatory B cell subset that suppresses effector T-cell function through STAT3-mediated IL-10 production. However, the mechanisms govern
Externí odkaz:
https://doaj.org/article/e083fa30bf44444692ed076413c733b3
Autor:
Satoshi Nishiwaki, Takayuki Nakayama, Makoto Murata, Tetsuya Nishida, Seitaro Terakura, Shigeki Saito, Tomonori Kato, Hiroki Mizuno, Nobuhiko Imahashi, Aika Seto, Yukiyasu Ozawa, Koichi Miyamura, Masafumi Ito, Kyosuke Takeshita, Hidefumi Kato, Shinya Toyokuni, Keisuke Nagao, Ryuzo Ueda, Tomoki Naoe
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96252 (2014)
Macrophage infiltration of skin GVHD lesions correlates directly with disease severity, but the mechanisms underlying this relationship remain unclear and GVHD with many macrophages is a therapeutic challenge. Here, we characterize the macrophages in
Externí odkaz:
https://doaj.org/article/468b77c852fb4228939587485914f9c9
Autor:
Nobuhiko Imahashi, Rafet Basar, Yuefan Huang, Fang Wang, Natalia Baran, Pinaki Prosad Banerjee, Junjun Lu, Ana Karen Nunez Cortes, Nadima Uprety, Emily Ensley, Luis Muniz-Feliciano, Tamara J Laskowski, Judy S Moyes, May Daher, Mayela Mendt, Lucila N Kerbauy, Mayra Shanley, Li Li, Francesca Lorraine Wei Inng Lim, Hila Shaim, Ye Li, Marina Konopleva, Michael Green, Jennifer Wargo, Elizabeth J Shpall, Ken Chen, Katayoun Rezvani
Publikováno v:
Journal for immunotherapy of cancer. 10(12)
BackgroundB cells play a pivotal role in regulating the immune response. The induction of B cell-mediated immunosuppressive function requires B cell activating signals. However, the mechanisms by which activated B cells mediate T-cell suppression are
Autor:
Nedyalko Petrov, Junjun Lu, Ana Karen Nunez Cortes, Mustafa H Bdiwi, Matthew S. McNeill, Lorenzo Brunetti, Li Li, Gonca Ozcan, Nobuhiko Imahashi, Ken Chen, Mollie S. Schubert, Duncan Mak, Lucila Nassif Kerbauy, Mark A. Behlke, Luis Muniz-Feliciano, Leiser Silva, Elizabeth J. Shpall, Enli Liu, Ali Rezvan, Natalie W. Fowlkes, Elif Gokdemir, Garrett R. Rettig, Richard Skinner, Xin Ru Jiang, Jing Wang, Vakul Mohanty, Mohsen Fathi, Yifei Shen, Yuanxin Xi, Mayela Mendt, Shahram Kordasti, Natalia Baran, Francesca Lorraine Wei Inng Lim, Nadima Uprety, Sonny Ang, Sunil Acharya, Pinaki P. Banerjee, Marina Konopleva, May Daher, Richard E. Champlin, Gavin Kurgan, Heng Li, Hila Shaim, Rolf Turk, Mecit Kaplan, Xinhai Wan, Mayra Shanley, Emily Ensley, David Marin, Rafet Basar, Navin Varadarajan, Shangrong Lyu, Katayoun Rezvani, Ye Li, Vandana Nandivada
Publikováno v:
2021, ' Targeting a cytokine checkpoint enhances the fitness of armored cord blood CAR-NK cells ', Blood, vol. 137, no. 5, pp. 624–636 . https://doi.org/10.1182/blood.2020007748
Immune checkpoint therapy has resulted in remarkable improvements in the outcome for certain cancers. To broaden the clinical impact of checkpoint targeting, we devised a strategy that couples targeting of the cytokine-inducible Src homology 2–cont
Autor:
Satoru Takada, Takahiro Fukuda, Yuta Katayama, Noriko Doki, Naoyuki Uchida, Yoshinobu Kanda, Tetsuya Eto, Nobuhiko Imahashi, Masayuki Hino, Junya Kanda, Masatsugu Tanaka, Jinichi Mori, Makoto Onizuka, Masamitsu Yanada, Yoshiko Atsuta, Satoshi Yamasaki, Yukiyasu Ozawa
Publikováno v:
Annals of Hematology. 99:2927-2937
This study aimed to analyze the factors associated with outcomes of bone marrow transplantation (UR-BMT) or cord blood stem cell transplantation from unrelated donors (UR-CBT). We assessed the time from diagnosis to transplantation among acute myeloi
Autor:
Eisei Kondo, Hitoshi Sakai, Masatsugu Tanaka, Takahiro Fukuda, Nobuhiko Imahashi, Jun Ishikawa, Naoyuki Uchida, Hikaru Kobayashi, Junya Kanda, Yoshiko Atsuta, Donor, Yoshihiro Inamoto, Shinichi Kako, Takafumi Kimura, Yasuji Kozai, Seitaro Terakura, Ken-ichi Matsuoka
Publikováno v:
Bone Marrow Transplantation. 55:2098-2108
To investigate which reduced-intensity conditioning (RIC)/reduced-toxicity conditioning (RTC) is superior for umbilical cord blood transplantation (UCBT) for lymphoid malignancies, we retrospectively compared three widely used RIC/RTC regimens: fluda
Autor:
Koji Kato, Takashi Ikeda, Junya Kanda, Makoto Onizuka, Jun Ishikawa, Mizuki Watanabe, Takahiro Fukuda, Nobuhiko Imahashi, Sung-Won Kim, Hikaru Kobayashi, Tatsuo Ichinohe, Eisei Kondo, Keisuke Kataoka, Naoyuki Uchida, Seitaro Terakura, Ken-ichi Matsuoka, Shuro Yoshida, Souichi Shiratori, Takafumi Kimura, Akihito Shinohara, Yoshiko Atsuta, Tadakazu Kondo
Publikováno v:
Bone marrow transplantation. 57(2)
We retrospectively compared the outcomes of reduced-intensity conditioning (RIC) transplantation from matched related donors (MRD; n = 266), matched unrelated donors (MUD; n = 277), and umbilical cord blood (UCB; n = 513) for mature lymphoid malignan