Výsledky vyhledávání - "Nobuhiko HOSHI"

Akademický článek

Ca2+ imaging with two-photon microscopy to detect the disruption of brain function in mice administered neonicotinoid insecticides

Autor: Anri Hirai, Shouta Sugio, Collins Nimako, Shouta M. M. Nakayama, Keisuke Kato, Keisuke Takahashi, Koji Arizono, Tetsushi Hirano, Nobuhiko Hoshi, Kazutoshi Fujioka, Kumiko Taira, Mayumi Ishizuka, Hiroaki Wake, Yoshinori Ikenaka

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)

Abstract Neonicotinoid pesticides are a class of insecticides that reportedly have harmful effects on bees and dragonflies, causing a reduction in their numbers. Neonicotinoids act as neuroreceptor modulators, and some studies have reported their ass

Externí odkaz: https://doaj.org/article/043eedf362e04a0e9e9345834d4e69da

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Akademický článek

Fabrication of a Novel Culture Dish Adapter with a Small Recess Structure for Flow Control in a Closed Environment

Autor: Reiko Yasuda, Shungo Adachi, Atsuhito Okonogi, Youhei Anzai, Tadataka Kamiyama, Keiji Katano, Nobuhiko Hoshi, Tohru Natsume, Katsuo Mogi

Publikováno v: Applied Sciences, Vol 9, Iss 2, p 269 (2019)

Cell culture medium replacement is necessary to replenish nutrients and remove waste products, and perfusion and batch media exchange methods are available. The former can establish an environment similar to that in vivo, and microfluidic devices are

Externí odkaz: https://doaj.org/article/5de68d1362134473a07c401004aa58ee

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Quantitative elucidation of the transfer of the neonicotinoid pesticide clothianidin to the breast milk in mice

Autor: Asuka, Shoda, Misaki, Nishi, Midori, Murata, Youhei, Mantani, Toshifumi, Yokoyama, Tetsushi, Hirano, Yoshinori, Ikenaka, Nobuhiko, Hoshi

Publikováno v: Toxicology Letters. 373:33-40

Neonicotinoid pesticides (NNs) have been reported to have neurobehavioral effects on offspring after fetal and lactational exposure. In this study, clothianidin (CLO), an NN, was administered orally as a single dose (6.5 mg/kg: 1/10 of the no-observe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a6a8e5cadcc280d3cbbed6b5ec1c621
https://hdl.handle.net/20.500.14094/0100477905

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Histological study on regional specificity of the mucosal nerve network in the rat large intestine

Autor: Satoki, Nakanishi, Youhei, Mantani, Nobuhiko, Ohno, Rinako, Morishita, Toshifumi, Yokoyama, Nobuhiko, Hoshi

Publikováno v: Journal of Veterinary Medical Science. 85:123-134

Our previous studies and others have revealed detailed characteristics of the mucosal nerve network in the small intestine, but much remains unknown about the corresponding network in the large intestine. We herein investigated regional differences i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25b7356a20ee896b5664acb31200f2b7
https://doi.org/10.1292/jvms.22-0433

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Effects of in utero and lactational exposure to the no-observed-adverse-effect level (NOAEL) dose of the neonicotinoid clothianidin on the reproductive organs of female mice

Autor: Misaki Nishi, Mizuki Maeda, Sayaka Kitauchi, Asuka Shoda, Nobuhiko Hoshi, Midori Murata, Yoshinori Ikenaka, Youhei Mantani, Toshifumi Yokoyama, Tetsushi Hirano, Yoshiaki Tabuchi

Publikováno v: The Journal of Veterinary Medical Science

Recently, developmental exposure to clothianidin (CLO) has been shown to cause reproductive toxicity in male mice, but the effects in female mice remain to be clarified. Pregnant C57BL/6N mice were given a no-observed-adverse-effect-level (NOAEL) dos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cd6beec7913b70092f2ba0c3c84099e
http://www.lib.kobe-u.ac.jp/handle_kernel/90008518

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Fetal and lactational exposure to the no-observed-adverse-effect level (NOAEL) dose of the neonicotinoid pesticide clothianidin inhibits neurogenesis and induces different behavioral abnormalities at the developmental stages in male mice

Autor: Youhei Mantani, Mizuki Maeda, Misaki Nishi, Midori Murata, Nobuhiko Hoshi, Asuka Shoda, Sayaka Kitauchi, Yoshinori Ikenaka, Toshifumi Yokoyama, Yoshiaki Tabuchi, Tetsushi Hirano

Publikováno v: The Journal of Veterinary Medical Science

Recently, it has been reported that neonicotinoid pesticides (NNs) are transferred from mother to child and are assumed to affect the next generation, but the behavioral effects of NN exposure at different developmental stages have not been investiga

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47f223aa144ae4cdcc099451e3cffacf
https://hdl.handle.net/20.500.14094/90008270

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Influence of acute exposure to a low dose of systemic insecticide fipronil on locomotor activity and emotional behavior in adult male mice

Autor: Youhei Mantani, Toshifumi Yokoyama, Mizuki Maeda, Nobuhiko Hoshi, Tetsushi Hirano, Yoshiaki Tabuchi, Sayaka Kitauchi

Publikováno v: The Journal of Veterinary Medical Science

Fipronil (FPN) is a systemic insecticide that antagonizes the gamma-aminobutyric acid type A (GABAA) receptors in insects. Recently, adverse effects of FPN on mammals have been reported, but most of those were caused by high doses of FPN and additive

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af482018ce99541e31a6db8174da735a
https://hdl.handle.net/20.500.14094/90008308

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