Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Nobuhide Tsuruoka"'
Autor:
Misuzu Fujita, Kengo Nagashima, Minobu Shimazu, Misae Suzuki, Ichiro Tauchi, Miwa Sakuma, Setsuko Yamamoto, Hideki Hanaoka, Makio Shozu, Nobuhide Tsuruoka, Tokuzo Kasai, Akira Hata
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract A self-sampling human papillomavirus (HPV) test could improve the morbidity and mortality of cervical cancer in Japan. However, its effectiveness and feasibility have not been demonstrated sufficiently. Hence, we launched a randomized contro
Externí odkaz:
https://doaj.org/article/cd174cd9705d483596565ef50f163dd2
Autor:
Misuzu Fujita, Kengo Nagashima, Minobu Shimazu, Misae Suzuki, Ichiro Tauchi, Miwa Sakuma, Setsuko Yamamoto, Hideki Hanaoka, Makio Shozu, Nobuhide Tsuruoka, Tokuzo Kasai, Akira Hata
Publikováno v:
PLoS ONE, Vol 18, Iss 6, p e0286909 (2023)
PurposeIn terms of medical policy for cervical cancer prevention, Japan lags far behind other industrialized countries. We initiated a randomized controlled trial to evaluate the self-sampling human papillomavirus (HPV) test as a tool to raise screen
Externí odkaz:
https://doaj.org/article/7450099a216c4b76ac281ccde53c8738
Autor:
Kengo Nagashima, Setsuko Yamamoto, Hideki Hanaoka, Makio Shozu, Misuzu Fujita, Akira Hata, Minobu Shimazu, Misae Suzuki, Ichiro Tauchi, Miwa Sakuma, Nobuhide Tsuruoka, Tokuzo Kasai
Publikováno v:
BMJ Open, Vol 12, Iss 2 (2022)
Externí odkaz:
https://doaj.org/article/a4ae63fcfd4340369a4e4671b5e61be3
Autor:
Takashi Ogasawara, Yuko Kohashi, Jun Ikari, Toshibumi Taniguchi, Nobuhide Tsuruoka, Haruko Watanabe-Takano, Lisa Fujimura, Akemi Sakamoto, Masahiko Hatano, Hirokuni Hirata, Yasutsugu Fukushima, Takeshi Fukuda, Kazuhiro Kurasawa, Koichiro Tatsumi, Takeshi Tokuhisa, Masafumi Arima
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Transcriptional repressor B-cell lymphoma 6 (Bcl6) appears to regulate TH2 immune responses in allergies, but its precise role is unclear. We previously reported that Bcl6 suppressed IL-4 production in naïve CD4+ T cell-derived memory TH2 cells. To
Externí odkaz:
https://doaj.org/article/d2fd1e26406c41e19cd9be331a9172e4
Autor:
Misuzu Fujita, Minobu Shimazu, Kengo Nagashima, Misae Suzuki, Ichiro Tauchi, Miwa Sakuma, Setsuko Yamamoto, Makio Shozu, Hideki Hanaoka, Nobuhide Tsuruoka, Tokuzo Kasai, Akira Hata
Publikováno v:
BMJ Open, Vol 12, Iss 2 (2022)
IntroductionRecently, the incidence of cervical cancer has increased in Japan, probably because of an interruption in human papillomavirus (HPV) vaccination and a low cervical cancer screening rate. There is a lack of evidence for self-sampling HPV t
Autor:
Akemi Sakamoto, Takashi Ogasawara, Haruko Watanabe-Takano, Lisa Fujimura, Yasutsugu Fukushima, Hirokuni Hirata, Yuko Kohashi, Nobuhide Tsuruoka, Kazuhiro Kurasawa, Jun Ikari, Toshibumi Taniguchi, Takeshi Fukuda, Masafumi Arima, Masahiko Hatano, Koichiro Tatsumi, Takeshi Tokuhisa
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Transcriptional repressor B-cell lymphoma 6 (Bcl6) appears to regulate TH2 immune responses in allergies, but its precise role is unclear. We previously reported that Bcl6 suppressed IL-4 production in naive CD4+ T cell-derived memory TH2 cells. To i
Publikováno v:
Oncology Reports. 33:744-750
Metformin is a diabetes drug with anticancer properties. Several studies have investigated the effects of metformin combined with chemotherapeutic agents, with controversial results. This study evaluated the efficacy of combined metformin/cisplatin t
Autor:
Kenji Matsumoto, Toshibumi Taniguchi, Yasutsugu Fukushima, Hirokuni Hirata, Kazuhiro Kurasawa, Lisa Fujimura, Masafumi Arima, Jun Ikari, Haruko Watanabe-Takano, Hirohisa Saito, Masahiko Hatano, Akemi Sakamoto, Susumu Nakae, Takeshi Tokuhisa, Nobuhide Tsuruoka, Hisae Satake, Koichiro Tatsumi, Takashi Ogasawara, Takeshi Fukuda, Kumiya Sugiyama
Publikováno v:
Proceedings of the National Academy of Sciences. 114
Mice deficient in the transcriptional repressor B-cell CLL/lymphoma 6 (Bcl6) exhibit similar T helper 2 (TH2) immune responses as patients with allergic diseases. However, the molecular mechanisms underlying Bcl6-directed regulation of TH2 cytokine g
Autor:
Daisuke Kitayama, Masafumi Arima, Eggi Arguni, Masahiko Hatano, Nobuhide Tsuruoka, Takeshi Tokuhisa, Akemi Sakamoto, Thoru Saito
Publikováno v:
Immunology Letters. 110:145-151
IL-21 has a pro-apoptotic effect on freshly isolated B cells stimulated with LPS, and also induces Bcl6 expression in the activated B cells. However, a role for Bcl6 in the activated B cells is not known. When naive B cells from Bcl6-deficient mice w
Autor:
Masafumi Arima, Takeshi Tokuhisa, Nobue Takeda, Masahiko Hatano, Seiji Okada, Yoichi Kohno, Akemi Sakamoto, Nobuhide Tsuruoka
Publikováno v:
The Journal of Immunology. 171:426-431
Bcl6 functions as a sequence-specific transcriptional repressor, and Bcl6-deficient (Bcl6−/−) mice have been reported to display Th2-type inflammatory diseases in multiple organs. Since IL-18 is a potent stimulator of Th2 cells, we examined the e