Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Nobuhide Takifuji"'
Autor:
Nobuhide Takifuji, Harumichi Ikegami, Shunichi Negoro, Takanobu Hoso, Takashi Nakano, Kiyoyuki Furuse, Yoshiki Takada, Fumiyuki Iwami, Yasufumi Yamaji, Hiroshi Senba, Shinichiro Nakamura, Jun Araki, Shin-ichi Hayasaka, Koji Takeda, Masahiro Fukuoka
Publikováno v:
Investigational New Drugs. 25:377-383
Purpose: We conducted a multicenter phase II study of amrubicin, a novel 9-aminoanthracycline, to evaluate its efficacy and safety in patients with non-small-cell lung cancer (NSCLC). Patients and methods: Entry requirements included cytologically or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::997ebc4a3585c64facc0c770829c548a
https://doi.org/10.1007/s10637-007-9039-6
https://doi.org/10.1007/s10637-007-9039-6
Autor:
Nobuhide Takifuji, Takashi Kuwabara, Noriyuki Masuda, Shinzoh Kudoh, Takashi Yana, Masahiro Fukuoka, Tomonori Hirashima, Kaoru Matsui, Noriaki Kurata, Satoshi Kobayashi, Shunichi Negoro, Minoru Takada, K. Takeda
Publikováno v:
Investigational New Drugs. 16:245-254
(E)-2'-deoxy-2'-(fluoromethylene)cytidine (FMdC), one of the most potent inhibitors of ribonucleoside diphosphate reductase, was selected for clinical development because of its novel mechanisms of action, and strong antitumor activity against experi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70a7849f5fe765738abccf784591c4d2
https://doi.org/10.1023/a:1006126212481
https://doi.org/10.1023/a:1006126212481
Autor:
T. Hirashima, Takashi Yana, Atsuko Yoshikawa, Minoru Takada, Kazuhiko Nakagawa, Shinzoh Kudoh, Nobuhide Takifuji, Shunichi Negoro, Yoko Kusunoki, Kaoru Matsui, Masahiro Fukuoka, Noriyuki Masuda
Publikováno v:
Japanese Journal of Cancer Research : Gann
Two phase I trials of irinotecan (CPT-11) in combination with cisplatin were conducted. In both cases, the dose-limiting toxicities were leukopenia and/or diarrhea. During these trials the pharmacokinetics of CPT-11 and its active metabolite, 7-ethyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc827b87d992cbfe5c3cd4e6e5f1e83d
https://doi.org/10.1111/j.1349-7006.1995.tb03071.x
https://doi.org/10.1111/j.1349-7006.1995.tb03071.x
Autor:
Sumitaka Imamura, Nobuhide Takifuji, Shinei Ryu, Shunichi Negoro, Kaoru Matsui, Yoko Kusunoki, Noriyuki Masuda, Minoru Takada, Shinzoh Kudo, Masahiro Fukuoka
Publikováno v:
Cancer. 73:1608-1614
Background and Methods. Thirty-nine roentgenologically occult lung cancers in 29 patients were treated using photodynamic therapy (PDT) and/or thoracic radiotherapy (TRT) from January 1986 to March 1992. With the exception of one mixed-tumor case, al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adc690715d7f773b09556dc0c76a35ad
https://doi.org/10.1002/1097-0142(19940315)73:6<1608::aid-cncr2820730611>3.0.co
https://doi.org/10.1002/1097-0142(19940315)73:6<1608::aid-cncr2820730611>3.0.co
Publikováno v:
THE JOURNAL OF JAPAN SOCIETY FOR LASER SURGERY AND MEDICINE. 15:13-19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b8951c3aee30aed85fa4a9e2f5b4adf
https://doi.org/10.2530/jslsm1980.15.1_13
https://doi.org/10.2530/jslsm1980.15.1_13
Autor:
Minoru Takada, Nobuhide Takifuji, Kaoru Matsui, Masahiro Fukuoka, S. Negoro, S. Kudoh, Noriyuki Masuda, Yoko Kusunoki, S Kishimoto, Kazuhiko Nakagawa
Publikováno v:
Journal of Clinical Oncology. 10:1775-1780
PURPOSE The purpose of this study was to determine the maximum-tolerated dose and the dose-limiting toxicities of CPT-11, a new derivative of camptothecin, in combination with a fixed dose of cisplatin in patients with non-small-cell lung cancer (NSC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e4315961e8da5d122ead8c4e3da6876
https://doi.org/10.1200/jco.1992.10.11.1775
https://doi.org/10.1200/jco.1992.10.11.1775
Autor:
Shunichi Negoro, Noriyuki Masuda, Yoko Kusunoki, Masayuki Nishioka, Kaoru Matsui, Minoru Takada, Shinzoh Kudoh, Masahiro Fukuoka, Nobuhide Takifuji, Kazuhiko Nakagawa
Publikováno v:
Journal of Clinical Oncology. 10:1225-1229
PURPOSE To evaluate the activity of CPT-11, which is a new derivative of camptothecin, against refractory or relapsed small-cell lung cancer (SCLC). PATIENTS AND METHODS Sixteen patients with refractory or relapsed SCLC were entered onto a prospectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f646214d69995ae1d85eb17df9be3d6
https://doi.org/10.1200/jco.1992.10.8.1225
https://doi.org/10.1200/jco.1992.10.8.1225
Autor:
Shinzo Kudoh, Y. Kusunoki, Kaoru Matsui, Nobuhide Takifuji, Sinei Ryu, Minoru Takada, Noriyuki Masuda, Masahiro Fukuoka, Shunichi Negoro
Publikováno v:
American Journal of Clinical Oncology. 15:18-22
Between August 1985 and June 1986, 49 previously untreated patients with locally advanced or metastatic non-small-cell lung cancer (NSCLC) were treated with the combination of cisplatin 80 mg/m2 i.v. on day 1, vindesine 3 mg/m2 i.v. on days 1 and 8,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::032892f82ae55eb9c05c7bfc891e1985
https://doi.org/10.1097/00000421-199202000-00004
https://doi.org/10.1097/00000421-199202000-00004
Autor:
Shinzoh Kudoh, Yoko Kusunoki, Kaoru Matsui, Shunichi Negoro, Noriyuki Masuda, Tetsuo Taguchi, Masahiro Fukuoka, Minoru Takada, Hisanobu Niitani, Nobuhide Takifuji
Publikováno v:
JNCI Journal of the National Cancer Institute. 83:1164-1168
7-Ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxy-camptothecin (CPT-11) is a novel camptothecin derivative that has been selected for clinical evaluation because of its broad spectrum of antitumor activity in animal models and its unique inhibito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5a9e10766a8050eee07f75755f6d9c2
https://doi.org/10.1093/jnci/83.16.1164
https://doi.org/10.1093/jnci/83.16.1164
Autor:
Kiyoyuki Furuse, Yamamoto M, Yoko Kusunoki, Nobuhide Takifuji, Kaoru Matui, Masaaki Kawahara, Kodama N, Shun‐iti Negoro, Masahiro Fukuoka, Minoru Takada, Kaoru Kubota
Publikováno v:
Cancer. 68:714-719
Between August 1983 and March 1985, a randomized study was conducted that compared cisplatin (CDDP) (80 mg/m2 on day 1) alone with CDDP plus vindesine (VDS) (3 mg/m2 on days 1, 8, and 15) in 160 consecutive patients with inoperable non-small cell lun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46d41d36c12e3028b4d34696bf09a7fc
https://doi.org/10.1002/1097-0142(19910815)68:4<714::aid-cncr2820680408>3.0.co
https://doi.org/10.1002/1097-0142(19910815)68:4<714::aid-cncr2820680408>3.0.co