Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Nobuaki Yokote"'
Autor:
Hiroshi Yamamoto, Hiroshi Nokihara, Reiko Ando Makihara, Ikuo Sekine, Yuichiro Ohe, Noboru Yamamoto, Tomohide Tamura, Nobuaki Yokote, Yoshinori Makino
Publikováno v:
Japanese Journal of Clinical Oncology. 42:1187-1191
Background: Severe hematological toxicity has been frequently observed during amrubicin monotherapy for patients with lung cancer despite the favorable anti-tumor response. The purpose of this retrospective study was to identify pretreatment factors
Autor:
Yu-ichiro Azuma, Nobuaki Yokote, Hiroshi Yamamoto, Yoshinori Makino, Akihiro Hirakawa, Kimie Sai, Masahiro Tohkin, Norifumi Morikawa, Yoshiro Saito, Yasuhiro Fujiwara, Ryoko Udagawa, Kojiro Hata, Yasuaki Ryushima
Publikováno v:
Biologicalpharmaceutical bulletin. 35(5)
Capecitabine, an oral prodrug of 5-fluorouracil (5-FU), is a promising treatment for colorectal, breast and gastric cancers, but often causes hand-foot syndrome (HFS), the most common dose-limiting toxicity. The current study was conducted to investi
Autor:
Tomomi, Sano, Toru, Akagi, Nobuaki, Yokote, Chio, Shuto, Naoko, Kudo, Kousuke, Miura, Satoshi, Murakami, Osamu, Saito, Hiroshi, Yamamoto, Motohiro, Matoba
Publikováno v:
Gan to kagaku ryoho. Cancerchemotherapy. 39(5)
In Japan, although oral oxycodone is widely used for cancer pain treatment, there is no injection preparation of oxycodone used as a single ingredient. Only the compound injection of oxycodone and hydrocotarnine has received approval. Subcutaneous ad
Autor:
Akiko, Kubo, Keiichi, Koido, Mari, Sawada, Yasuaki, Ryushima, Chikako, Shimizu, Tomoyasu, Kato, Masashi, Ando, Takayuki, Kinoshita, Koji, Murakoshi, Nobuaki, Yokote, Yasuhiro, Fujiwara, Hiroshi, Yamamoto
Publikováno v:
Gan to kagaku ryoho. Cancerchemotherapy. 39(3)
Treatment-related infertility is an important issue facing breast cancer survivors of childbearing age. A previous study at the National Cancer Center Hospital between 2000 and 2004 analyzed 136 postoperative breast cancer patients under 40 years old
Autor:
Yasuhide Yamada, Satoru Iwasa, Takako Yanai, Nobuaki Yokote, Hironobu Hashimoto, Tetsuya Hamaguchi, Natsuko Hori, Yasuhiro Shimada, Kouji Murakoshi, Ken Kato, Hiroshi Yamamoto
Publikováno v:
International journal of clinical oncology. 18(3)
The addition of bevacizumab to standard chemotherapy has significant clinical benefits in metastatic colorectal cancer. However, its use is often avoided due to patient condition or disease status. Of 228 consecutive patients receiving first-line FOL
Autor:
Hiroshi Nokihara, Tomohide Tamura, Hideo Kunitoh, Hitoshi Sato, Reiko Ando, Erika Sugiyama, Nobuaki Yokote, Yoshinori Makino, Ikuo Sekine, Chiharu Tanai, Yuichiro Ohe, Noboru Yamamoto, Yasushi Goto, Hajime Asahina, Hiroshi Yamamoto
Publikováno v:
Cancer chemotherapy and pharmacology. 69(4)
The pharmacokinetic (PK)–pharmacodynamic (PD) relationship of amrubicin and its active metabolite, amrubicinol, has only been evaluated using trough levels of these agents since the full PK profiles not yet been clarified so far. This study was per
Autor:
Tomohide Tamura, Hiroshi Yamamoto, Reiko Ando, Rena Nishigaki, Noboru Yamamoto, Takehiro Kimura, Nobuaki Yokote, Yoshinori Makino
Publikováno v:
Biomedical Chromatography.
A simple and sensitive high-performance liquid chromatographic (HPLC) method was developed for determination of amrubicin and its metabolite amrubicinol in human plasma. After protein precipitation with methanol without evaporation procedure, large v
Publikováno v:
Chemical and Pharmaceutical Bulletin. 33:4175-4181
A novel pterosin-type dinorsesquiterpene, mukagolactone (I), was isolated from the fronds of Monachosorum arakii TAGAWA (Pteridaceae), along with three new dinorsesquiterpene dimers, monachosorins A (II), B (III) and C (IV). Their structures were elu