Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Nobuaki Uehara"'
Autor:
Hiroyuki Tsuda, Masae Tatematsu, Masao Hirose, Hideki Wanibuchi, Yoichi Konishi, Tomoyuki Shirai, Katsumi Imaida, Nobuaki Uehara, Keiichirou Morimura, Dai Nakae, Fumio Furukawa, Min Wei, Tetsuya Tsukamoto, Shoji Fukushima, Keiji Wakabayashi, Yukari Totsuka
Publikováno v:
Japanese Journal of Cancer Research : Gann
For a long period, it has been generally considered that carcinogens, particularly genotoxic ones, have no threshold in exerting their potential for cancer induction. However, the non-threshold theory can be challenged with regard to assessment of ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::908e83bf7b3c5d7745a9f1e82d99de6c
http://europepmc.org/articles/PMC5926877
http://europepmc.org/articles/PMC5926877
Autor:
Kazunori Sekine, Malcolm A. Moore, Masakuni Degawa, Nobuo Takasuka, Yoshihiko Konno, Nobuaki Uehara, Kei Nakashita, Hiroyuki Tsuda
Publikováno v:
Cancer Letters. 143:229-234
In order to elucidate whether mixed exposure to environmental carcinogens and caffeine increases the risk of cancer induction, we investigated the relationship between preneoplastic lesion development in the liver and colon and drug metabolizing enzy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fcf3ae1950f5cbf6661b455507a1e8a
https://doi.org/10.1016/s0304-3835(99)00130-5
https://doi.org/10.1016/s0304-3835(99)00130-5
Autor:
Masaaki Iigo, Hidehiko Beppu, Yoshio Iwahori, Iwao Hirono, Masafumi Nakayama, Nobuaki Uehara, Kazuyuki Matsumoto, Hiroyasu Baba-Toriyama, Minako Nagao, Masakuni Degawa, Masako Ochiai, Keisuke Fujita, Hiroyuki Tsuda, Makoto Asamoto
Publikováno v:
Japanese Journal of Cancer Research : Gann
To assess mechanisms of chemoprevention of hepatocarcinogenesis by trans-beta-carotene (beta-C), DL-alpha-tocopherol (alpha-T), and freeze-dried whole leaves of Kidachi aloe (Aloe), formation of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ)-DNA adduct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a1842e154ec4c80f3eda4173f8a8999
https://doi.org/10.1111/j.1349-7006.1996.tb00228.x
https://doi.org/10.1111/j.1349-7006.1996.tb00228.x
Autor:
Hiroshi Miyazaki, Takayuki Hirose, Youichi Aizawa, Nobuaki Uehara, Nobuyoshi Kosaka, Nami Nogawa-Kosaka, Norio Komatsu, Takashi Kato, Kazumichi Nagasawa
Publikováno v:
Experimental hematology. 38(5)
Objective Erythropoietin (EPO) and its receptor (EPOR) are key regulators of red blood cell production in mammals and fish. We aimed to investigate the structural and functional conservation of the EPO-EPOR system in amphibian erythropoiesis, using X
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b9bc290a19de6023181aa35f6330e2c
https://pubmed.ncbi.nlm.nih.gov/20193733
https://pubmed.ncbi.nlm.nih.gov/20193733
Publikováno v:
Carbohydrate Research. 217:181-190
The relationship between the conformation of (1→3)-β- d -glucans in gel or hydrated form and the stimulation of two types of biological responses, namely, activation of coagulation Factor G from limulus amebocyte lysate (LAL) and host-mediated ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3694398a3ef06717da4fb5950253b968
https://doi.org/10.1016/0008-6215(91)84128-2
https://doi.org/10.1016/0008-6215(91)84128-2
Publikováno v:
Polymer Journal. 22:689-695
1-Acryloyloxyethylcarbamoyl-5-fluorouracil (1) was prepared by the reaction of 5-fluorouracil and 1-acryloyloxyethyl isocyanate. Various kinds of vinyl polymers were prepared by radical polymerizations of 1, with methyl acrylate, vinylimidazole, acry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::184e2c4a41c9d0e1d30497cea4a0a19c
https://doi.org/10.1295/polymj.22.689
https://doi.org/10.1295/polymj.22.689
Autor:
Hideki Kishida, Katsumi Imaida, Hiroyuki Tsuda, Fumio Furukawa, Tomoyuki Shirai, Tetsuya Tsukamoto, Keiichiro Morimura, Shuji Iwai, Shoji Fukushima, Dai Nakae, Nobuaki Uehara, Hideki Wanibuchi, Masae Tatematsu, Masao Hirose
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 80(1)
Until recently it has been generally considered that genotoxic carcinogens have no threshold in exerting their potential for cancer induction. However, the nonthreshold theory can be challenged with regard to assessment of cancer risk to humans. In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7db152e57ea4288be55e12b6209c1112
https://pubmed.ncbi.nlm.nih.gov/15014208
https://pubmed.ncbi.nlm.nih.gov/15014208
Autor:
Nobuo Takasuka, Nobuaki Uehara, Hiroyuki Tsuda, Cheol Beom Park, Baba-Toriyama Hiroyasu, Dae Joong Kim
Publikováno v:
Cancer letters. 139(2)
2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) is a very potent mutagen which induces tumors in the liver, lung and hematopoietic system of CDF1 mice and the liver, Zymbal gland and skin in F344 rats. The recent development of transgenic knock
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c4d2fba1d8f6134ce84ea4a41a3e3ea
https://pubmed.ncbi.nlm.nih.gov/10395176
https://pubmed.ncbi.nlm.nih.gov/10395176
Autor:
Dae Joong Kim, Hoyoku Nishino, Hiroyasu Baba-Toriyama, Masaaki Iigo, Nobuaki Uehara, Tadao Kakizoe, Michiaki Murakoshi, Yoshio Iwahori, Makoto Asamoto, Nobuo Takasuka, Hiroyuki Tsuda, Jin Man Kim, Takaaki Hori
Publikováno v:
Food Factors for Cancer Prevention ISBN: 9784431670193
The chemopreventive effect of α-carotene, β-carotene, and α-tocopherol α-TC) on liver and lung carcinogenesis was examined in B6C3F1 mice initiated with diethylnitrosamine (DEN) and N-methyl-AT-nitrosourea (MNU) during the initial 6 weeks. Group
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34ae5f1ea9193b914ceb33460eb550f9
https://doi.org/10.1007/978-4-431-67017-9_104
https://doi.org/10.1007/978-4-431-67017-9_104
Autor:
Yoshio Iwahori, Makoto Asamoto, Nobuo Takasuka, Masae Tatematsu, Takayuki Tsuchiya, Dae Joong Kim, Mamoru Mutai, Hiroyuki Tsuda, Takaaki Hori, Vladimir Krutovskikh, Hiroshi Yamasaki, Nobuaki Uehara, Hiroyasu Baba-Toriyama, Tomonori Ota
Publikováno v:
Carcinogenesis. 17(11)
Two different types of focal preneoplastic lesions, tentatively named Type I and II lesions, were recognized in the liver of rats chronically treated with clofibrate for 104 weeks. Type I lesions were characterized by mostly negative glucose-6-phosph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4d2b68e1b6ed11d726003555e451b09
https://pubmed.ncbi.nlm.nih.gov/8968061
https://pubmed.ncbi.nlm.nih.gov/8968061