Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Nobuaki Miyawaki"'
Autor:
Nobuaki Miyawaki, Asaka Tonouchi, Kouichi Kawazu, Kenji Ueda, Takahiro Akaishi, Atsushi Shimazaki
Publikováno v:
Journal of Ocular Pharmacology and Therapeutics. 31:518-524
To assess the usefulness of 0.0015% tafluprost and 0.5% timolol fixed-dose combination (TT-FDC) for glaucoma, the ocular hypotensive effect of TT-FDC and concentration of tafluprost and timolol in the aqueous humor were compared with those of the con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e694be037a40e78656db6cc12e12d2fb
https://doi.org/10.1089/jop.2015.0031
https://doi.org/10.1089/jop.2015.0031
Autor:
Shinji Yoneda, Hidenobu Tanihara, Wakana Goto, Hideaki Hara, Noriaki Kido, Yoshihito Honda, Nobuaki Miyawaki
Publikováno v:
Experimental Eye Research. 73:661-667
Two types of experiment were performed to examine the role of interleukin-1beta in ischemia-induced damage in the rat retina. In the in vivo study, enzyme-linked immunosorbent assay was used to investigate the expression of immunoreactive interleukin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::541cc742d7e3014c11f889aa7a82fcdf
https://doi.org/10.1006/exer.2001.1072
https://doi.org/10.1006/exer.2001.1072
Publikováno v:
European Journal of Pharmacology. 322:243-247
The influence of semotiadil fumarate, a novel vasoselective Ca2+ channel antagonist with a benzothiazine skeleton, was measured on the high-threshold Ca2+ current ICa,L in guinea-pig ventricular myocytes prepared by coronary perfusion with collagenas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff1342633ff664e343bc9125b25fb65f
https://doi.org/10.1016/s0014-2999(96)00995-8
https://doi.org/10.1016/s0014-2999(96)00995-8
Publikováno v:
Experimental eye research. 119
We investigated the effects of Src-family tyrosine kinase (SFK) inhibitors on intraocular pressure (IOP) and trabecular meshwork (TM) cells. The SFK inhibitors, PP2, PP1, and damnacanthal, significantly lowered IOP from baseline following intracamera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::378723a7356d6e019885b42f6140a75d
https://pubmed.ncbi.nlm.nih.gov/24321889
https://pubmed.ncbi.nlm.nih.gov/24321889
Autor:
Yoshifumi Watanabe, Tatsuya Nishi, Toshiro Shibano, Nobuaki Miyawaki, Daisuke Shii, Toshio Honda, Ken Osanai
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 6:1923-1926
Aliphatic and aromatic azido derivatives of semotiadil ( 1 ), a novel calcium antagonist with a 1,4-benzothiazine skeleton, were synthesized for developing photoaffinity probes of L type calcium channels. The azidophenoxy derivative 12 proved to be a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7de481e1fadcc176f9c04054256e0c5
https://doi.org/10.1016/0960-894x(96)00338-1
https://doi.org/10.1016/0960-894x(96)00338-1
Publikováno v:
Cardiovascular Drug Reviews. 14:135-147
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3357a3e160e5d37fc302a475f5dd9226
https://doi.org/10.1111/j.1527-3466.1996.tb00223.x
https://doi.org/10.1111/j.1527-3466.1996.tb00223.x
Publikováno v:
Drug Development Research. 22:293-298
The electrophysiological and antiarrhythmic effects of a structurally novel compound, SD-3212, were evaluated in comparison with its enantiomer (SD-3211). In isolated guinea pig ventricular muscles, SD-3212 reduced the maximum upstroke velocity and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54b047cef65f54d16b14f72999dd7490
https://doi.org/10.1002/ddr.430220310
https://doi.org/10.1002/ddr.430220310
Autor:
Takahiro, Akaishi, Atsushi, Shimazaki, Takeshi, Matsugi, Nobuaki, Miyawaki, Hideaki, Hara, Yasuaki, Kuwayama
Publikováno v:
Nippon Ganka Gakkai zasshi. 107(9)
To establish a telemetry system for measuring intraocular pressure (IOP) in rabbits and to evaluate the effects of topical application of ocular hypotensive agents on the circadian rhythm of IOP.We developed a telemetry system in rabbits housed under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4f2dbc8a5fe4ab21d698c9724e0e1a50
https://pubmed.ncbi.nlm.nih.gov/14531310
https://pubmed.ncbi.nlm.nih.gov/14531310
Autor:
Wakana Goto, Kouichi Kawazu, Nobuo Morikawa, Yasuo Tano, Takashi Ota, Nobuaki Miyawaki, Yasumasa Otori, Hideaki Hara
Publikováno v:
Brain research. 958(1)
The purpose of this study was to determine whether timolol, an ocular hypotensive drug, has retinal neuroprotective effects in experimental in vitro and in vivo models. For in vitro studies, we used retinal neuron cultures from rat embryos and purifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67e6b9b0d499b9bcafd2ed3f4c2c2c23
https://pubmed.ncbi.nlm.nih.gov/12468025
https://pubmed.ncbi.nlm.nih.gov/12468025
Publikováno v:
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics. 18(3)
To determine if optic nerve axotomy affects the cell soma size of retinal ganglion cells and to establish whether such quantitative analysis is useful as a new way of evaluating retinal ganglion cell damage, we measured the changes in both the number
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0983aaa79302f024fcebf03a0e5cfca
https://pubmed.ncbi.nlm.nih.gov/12099545
https://pubmed.ncbi.nlm.nih.gov/12099545