Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Nobuaki Kikyo"'
Autor:
Nobuko Katoku-Kikyo, Seunghyun Lim, Ce Yuan, Jinsha Koroth, Yasushi Nakagawa, Elizabeth W Bradley, Nobuaki Kikyo
Publikováno v:
PLoS Biology, Vol 21, Iss 12, p e3002419 (2023)
Circadian regulation of gene expression is prevalent and plays critical roles in cell differentiation. However, its roles in the reprogramming of differentiated cells remain largely unknown. Here, we found that one of the master circadian regulators
Externí odkaz:
https://doaj.org/article/4ba4a86f10464326a36d2cd82a1c2fe5
Autor:
Matthew Lowe, Jacob Lage, Ellen Paatela, Dane Munson, Reilly Hostager, Ce Yuan, Nobuko Katoku-Kikyo, Mercedes Ruiz-Estevez, Yoko Asakura, James Staats, Mulan Qahar, Michaela Lohman, Atsushi Asakura, Nobuaki Kikyo
Publikováno v:
Cell Reports, Vol 22, Iss 8, Pp 2118-2132 (2018)
Summary: Circadian rhythms regulate cell proliferation and differentiation; however, little is known about their roles in myogenic differentiation. Our synchronized differentiation studies demonstrate that myoblast proliferation and subsequent myotub
Externí odkaz:
https://doaj.org/article/83a1fd5ac5f940b095a88cb08937ef28
Publikováno v:
Stem Cell Research, Vol 15, Iss 3, Pp 469-480 (2015)
Leukemia inhibitory factor (LIF) is widely used to establish and maintain naïve pluripotent stem cells, including mouse embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs). Although the combination of chemical inhibitors called 2i
Externí odkaz:
https://doaj.org/article/a385cf2cc2a54b3f86c894ef67675b80
Publikováno v:
Stem Cell Research, Vol 15, Iss 2, Pp 384-386 (2015)
It has been very difficult, if not impossible, to establish mouse induced pluripotent stem cells (iPSCs) from differentiated cells, such as fibroblasts, without leukemia inhibitory factor (LIF). We have established and maintained LIF-independent iPSC
Externí odkaz:
https://doaj.org/article/bc046d0bee7046398db2b3d33595260b
Autor:
Hiroyuki Hirai, Nobuaki Kikyo
Publikováno v:
Genomics Data, Vol 7, Iss , Pp 171-172 (2016)
Genome-wide expression patterns of mRNA were compared between mouse embryonic fibroblasts (MEFs), embryonic stem cells (ESCs), and various types of induced pluripotent stem cells (iPSCs). iPSCs were established and maintained using modified Oct4 with
Externí odkaz:
https://doaj.org/article/5a9d214d855b4d4cb02decb50162c859
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e34149 (2012)
A major difficulty of producing induced pluripotent stem cells (iPSCs) has been the low efficiency of reprogramming differentiated cells into pluripotent cells. We previously showed that 5% of mouse embryonic fibroblasts (MEFs) were reprogrammed into
Externí odkaz:
https://doaj.org/article/58d0648dfcbe415892e0d31b345fb6ae
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39022 (2012)
Human induced pluripotent stem cells (iPSCs) can be divided into a leukemia inhibitory factor (LIF)-dependent naïve type and a basic fibroblast growth factor (bFGF)-dependent primed type. Although the former are more undifferentiated than the latter
Externí odkaz:
https://doaj.org/article/00a4ff5e4afb4a6ba7afdac262b67811
Autor:
Ellen Paatela, Seunghyun Lim, Dane Munson, Britney Lee, Daniel L. Houtz, Nobuaki Kikyo, Xuerui Wang, Ce Yuan, Nobuko Katoku-Kikyo, Atsushi Asakura, Jasmeet Bhatia, Yoko Asakura, Mohammed Hussein
Publikováno v:
The Journal of Cell Biology
Katoku-Kikyo et al. show that the circadian master regulators Per1 and Per2 control the efficiency of myoblast differentiation via Igf2 activation. This pathway creates a preferred circadian time window for myoblast differentiation in vitro and muscl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c03cb70e519479eb348b2e77d5dcf35e
https://pubmed.ncbi.nlm.nih.gov/34009269
https://pubmed.ncbi.nlm.nih.gov/34009269
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 9, p 2263 (2019)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Circadian rhythms regulate over 40% of protein-coding genes in at least one organ in the body through mechanisms tied to the central circadian clock and to cell-intrinsic auto-regulatory feedback loops. Distinct diurnal differences in regulation of r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70607b02430d8097bfcd9b7788ff197c
https://www.mdpi.com/1422-0067/20/9/2263
https://www.mdpi.com/1422-0067/20/9/2263
Publikováno v:
Stem Cell Research, Vol 15, Iss 3, Pp 469-480 (2015)
Leukemia inhibitory factor (LIF) is widely used to establish and maintain naïve pluripotent stem cells, including mouse embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs). Although the combination of chemical inhibitors called 2i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2225ba9d2bd2edf89a3dafc92ec9cbf3
https://doi.org/10.1016/j.scr.2015.09.002
https://doi.org/10.1016/j.scr.2015.09.002