Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Nobuaki, Waizumi"'
Autor:
Alexandros Papanikolaou, Elaine E. Tseng, Noguchi Hirohide, Michael Aaron Brodney, Michelle Vanase-Frawley, Laura McDowell, Nobuaki Waizumi, Katherine Fisher, Aarti Sawant-Basak, Betty Pettersen, Elena M. Drummond, David M. Rubitski, Anne W. Schmidt, Kim Jonelle Stutzman-Engwall, David E. Johnson, Emily L. Hudson, Sarah Grimwood, Karen J. Coffman
Publikováno v:
Journal of Medicinal Chemistry. 55:9240-9254
The cognitive impairments observed in Alzheimer’s disease (AD) are in part a consequence of reduced acetylcholine (ACh) levels resulting from a loss of cholinergic neurons. Preclinically, serotonin 4 receptor (5-HT4) agonists are reported to modula
Autor:
Nobuaki Waizumi, Ken ichi Ohno, Hidetoshi Tokuyama, Takeshi Fukushima, Kazuhiro Imai, Masako Maeda, Tomofumi Santa
Publikováno v:
Analytical Chemistry. 74:4391-4396
A rapid, simple and nonhazardous assay method for endcrine disruptors was developed using an estrogen receptor (ER) and fluorescence polarization (FP). Among the fluorescent compounds, the 17alpha-fluorescein-labeled estradiol derivative was selected
Publikováno v:
Tetrahedron Letters. 39:6015-6018
An efficient synthesis of bicyclic diketone 3, possessing most of the functional groups and stereogenic centers required for construction of the unique skeletons of CP-225,917 (1) and CP-263,114 (2), was achieved by utilizing an intramolecular Diels-
Autor:
Michael A, Brodney, David E, Johnson, Aarti, Sawant-Basak, Karen J, Coffman, Elena M, Drummond, Emily L, Hudson, Katherine E, Fisher, Hirohide, Noguchi, Nobuaki, Waizumi, Laura L, McDowell, Alexandros, Papanikolaou, Betty A, Pettersen, Anne W, Schmidt, Elaine, Tseng, Kim, Stutzman-Engwall, David M, Rubitski, Michelle A, Vanase-Frawley, Sarah, Grimwood
Publikováno v:
Journal of medicinal chemistry. 55(21)
The cognitive impairments observed in Alzheimer's disease (AD) are in part a consequence of reduced acetylcholine (ACh) levels resulting from a loss of cholinergic neurons. Preclinically, serotonin 4 receptor (5-HT(4)) agonists are reported to modula
Publikováno v:
Tetrahedron Letters. 35:7813-7816
A-Ring fragment of taxol (2), α-hydroxy aldehyde 1, was enantioselectively prepared by using asymmetric dihydroxylation of enol silyl ether of the parent aldehyde.
Publikováno v:
ChemInform. 26
A-Ring fragment of taxol (2), α-hydroxy aldehyde 1, was enantioselectively prepared by using asymmetric dihydroxylation of enol silyl ether of the parent aldehyde.
Publikováno v:
ChemInform. 29
An efficient synthesis of bicyclic diketone 3, possessing most of the functional groups and stereogenic centers required for construction of the unique skeletons of CP-225,917 (1) and CP-263,114 (2), was achieved by utilizing an intramolecular Diels-
Publikováno v:
ChemInform. 36
Publikováno v:
Journal of the American Chemical Society. 127(20)
This communication describes a concise and efficient total synthesis of mycalamide A by the convergent coupling of pederic acid unit with the mycalamine unit. The left-half, (+)-7-benzoylpederic acid, was synthesized from (2R,3R)-3-methylpent-4-en-2-
Publikováno v:
ChemInform. 35