Zobrazeno 1 - 10
of 483
pro vyhledávání: '"Nobuaki, Takahashi"'
Autor:
Yutaka Furutani, Yoshinori Hirano, Mariko Toguchi, Shoko Higuchi, Xian-Yang Qin, Kaori Yanaka, Yumi Sato-Shiozaki, Nobuaki Takahashi, Marina Sakai, Pornparn Kongpracha, Takehiro Suzuki, Naoshi Dohmae, Mutsuko Kukimoto-Niino, Mikako Shirouzu, Shushi Nagamori, Harukazu Suzuki, Kaoru Kobayashi, Takahiro Masaki, Hiroo Koyama, Kazuma Sekiba, Motoyuki Otsuka, Kazuhiko Koike, Michinori Kohara, Soichi Kojima, Hideaki Kakeya, Tomokazu Matsuura
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-13 (2023)
Abstract IFN-alpha have been reported to suppress hepatitis B virus (HBV) cccDNA via APOBEC3 cytidine deaminase activity through interferon signaling. To develop a novel anti-HBV drug for a functional cure, we performed in silico screening of the bin
Externí odkaz:
https://doaj.org/article/a95194b3f0af40dea3e8ffa9ef2e29cd
Autor:
Julia Tietz, Tea Gunde, Stefan Warmuth, Christopher Weinert, Matthias Brock, Alexandre Simonin, Christian Hess, Maria Johansson, Fabio Spiga, Simone Muntwiler, Belinda Wickihalder, Dana Mahler, Dania Diem, Julia Zeberer, Robin Heiz, Naomi Flückiger, Noriko Shiraishi, Yoshihide Miyake, Nobuaki Takahashi, Markus Fehrholz, Marta Bertolini, Peter Lichtlen, David Urech, Daniel Snell
Publikováno v:
JID Innovations, Vol 4, Iss 2, Pp 100258- (2024)
Inhibition of IL-4/IL-13 signaling has dramatically improved the treatment of atopic dermatitis (AD). However, in many patients, clinical responses are slow to develop and remain modest. Indeed, some symptoms of AD are dependent on IL-31, which is on
Externí odkaz:
https://doaj.org/article/3a75a4014dc34c0e9ce5224f697c7026
Autor:
Reiko Sakaguchi1,2,3, Nobuaki Takahashi1,4, Takashi Yoshida1,5, Nozomi Ogawa1, Yoshifumi Ueda1, Satoshi Hamano1, Kaori Yamaguchi6, Seishiro Sawamura1, Shinichiro Yamamoto1,5, Yuji Hara1,7, Tomoya Kawamoto1, Ryosuke Suzuki1, Akito Nakao1, Masayuki X. Mori1,3, Tetsushi Furukawa8, Shunichi Shimizu5, Ryuji Inoue9, Yasuo Mori1,2,4 mori@sbchem.kyoto-u.ac.jp
Publikováno v:
Journal of Biological Chemistry. Sep2024, Vol. 300 Issue 9, p1-21. 21p.
Publikováno v:
Folia Pharmacologica Japonica; 2024, Vol. 159 Issue 3, p165-168, 4p
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Psychiatric disorders are caused by complex and diverse factors, and numerous mechanisms have been proposed for the pathogenesis of these disorders. Accumulating evidence suggests that oxidative stress is one of the general factors involved in the pa
Externí odkaz:
https://doaj.org/article/94d564317c3f4c54895cd46d4a5633f5
Autor:
Sichong Chen, Nobuaki Takahashi, Changping Chen, Jordan L. Pauli, Chiharu Kuroki, Jun Kaminosono, Hideki Kashiwadani, Yuichi Kanmura, Yasuo Mori, Shaowu Ou, Liying Hao, Tomoyuki Kuwaki
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Transient receptor potential ankyrin 1 (TRPA1) is a non-selective cation channel that is broadly expressed in sensory pathways, such as the trigeminal and vagus nerves. It is capable of detecting various irritants in inspired gasses and is activated
Externí odkaz:
https://doaj.org/article/b3fc70d4cbcb436aab6ee869be475794
Autor:
Hiroshi Namisaki, Seiji Saito, Keiko Hiraishi, Tomoko Haba, Yoshitaka Tanaka, Hideaki Yoshida, Shigeru Iida, Nobuaki Takahashi
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229027 (2020)
Human immunoglobulin G isotype 4 (IgG4) antibodies are suitable for use in either the antagonist or agonist format because their low effector functions prevent target cytotoxicity or unwanted cytokine secretion. However, while manufacturing therapeut
Externí odkaz:
https://doaj.org/article/97be0e850231429b9c89aa2ba59371be
Publikováno v:
International Journal of Affective Engineering; 2024, Vol. 23 Issue 1, p63-73, 11p
Autor:
Nobuaki Takahashi, Mitsutoshi Tominaga, Ryohei Kosaka, Yayoi Kamata, Yoshie Umehara, Hironori Matsuda, Azumi Sakaguchi, Hideoki Ogawa, Kenji Takamori
Publikováno v:
Acta Dermato-Venereologica, Vol 97, Iss 8, Pp 928-933 (2017)
The pathogenesis of psoriatic itch is poorly understood. The aim of this study was to investigate the involvement of opioid receptors in scratching behaviour of imiquimod-induced psoriasis-like dermatitis model mice. Topical application of 5% imiquim
Externí odkaz:
https://doaj.org/article/21817a7fdc6348d897c358270c1afa82
Autor:
Yutaka Furutani, Mariko Toguchi, Yumi Shiozaki-Sato, Xian-Yang Qin, Etsuko Ebisui, Shoko Higuchi, Masayuki Sudoh, Harukazu Suzuki, Nobuaki Takahashi, Koichi Watashi, Takaji Wakita, Hideaki Kakeya, Soichi Kojima
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0216139 (2019)
Oral administration of nucleotide analogues and injection of interferon-α (IFNα) are used to achieve immediate suppression in replication of hepatitis B virus (HBV). Nucleotide analogs and IFNα inhibit viral polymerase activity and cause long-term
Externí odkaz:
https://doaj.org/article/6b9453cdc3c64cf995c7c25621ba35c9