Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Noboru Yata"'
Autor:
Yuya Yamashiro, Yuka Yanai, Tsutomu Takeda, Takuo Hayashi, Yoichi Akazawa, Noboru Yatagai, Hiroya Ueyama, Hidetaka Eguchi, Akihito Nagahara, Takashi Yao, Tsuyoshi Saito
Publikováno v:
JGH Open, Vol 6, Iss 8, Pp 531-538 (2022)
Abstract Background and Aim Juvenile polyposis (JP) is a rare disease known to be associated with mutations either in SMAD4/BMPR1A. JP is known to often develop into malignant tumors, with a reported probability of 9–50%. However, the mechanisms of
Externí odkaz:
https://doaj.org/article/ccabd013082e425a9556b3f86d7fffb7
Autor:
Teruo Murakami, Kaoru Ohoku, Noboru Yata, Michiko Yoshii, Ryoko Yumoto, Takahiko Hoshita, Taiju Kuramoto, Mizuho Une
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 49:111-117
Effect of 5 alpha-cyprinol sulfate, a bile alcohol sulfate specific to carp bile, on rectal membrane permeability to sodium ampicillin (AMP Na) was examined in rats. AMP Na is not easily absorbed through rat rectal membrane without aid. 5 alpha-Cypri
Publikováno v:
Journal of Drug Targeting. 7:233-240
The purpose of this research is to clarify the feasibility and to determine the extent of transnasal drug delivery to the brain through the cerebrospinal fluid (CSF) in the rat, using 3H-5-fluorouracil (5FU) as a model drug. It was confirmed first th
Publikováno v:
Journal of Drug Targeting. 6:405-414
To enhance the topical delivery of rhodamine B base (Rho), a model lipophilic compound, the electrostatic interaction between the positive and negative components incorporated in the liposomal bilayer was utilized. The higher in vitro permeability to
Autor:
Shunsuke Sato, Hironori Tsuzura, Yuji Kita, Yuji Ikeda, Daishi Kabemura, Sho Sato, Nozomi Amano, Noboru Yatagai, Ayato Murata, Yuji Shimada, Takuya Genda
Publikováno v:
JGH Open, Vol 5, Iss 10, Pp 1203-1209 (2021)
Abstract Aims Recent advances of direct‐acting antiviral drugs for hepatitis C virus (HCV) have dramatically improved the sustained virologic response (SVR) rate, but hepatocellular carcinoma (HCC) development rarely occurs even in patients who ach
Externí odkaz:
https://doaj.org/article/3c85d0fa3df04e1391f469f4ed4c6b61
Publikováno v:
Journal of Pharmacy and Pharmacology. 50:459-465
Kidney-specific delivery of p-nitroaniline, sulphamethoxazole and sulphamethizole after either intravenous administration of the L-γ-glutamyl or N-acetyl-L-γ-glutamyl derivatives or the parent drugs has been examined in a rat model. All L-γ-glutam
Autor:
Mikihisa Takano, Teruo Murakami, Masahiko Sato, Atsuko Okochi, Yutaka Higashi, Noboru Yata, Fumiko Higashikawa
Publikováno v:
Journal of Pharmacy and Pharmacology. 50:425-430
The hepatic clearance of ONO-5046 (N-[2-[4-(2,2-dimethylpropionyloxy)phenylsulphonyl-amino]benzoyl]aminoacetic acid), a low-molecular-weight neutrophil elastase inhibitor, has been investigated in rats and in the rat perfused liver. This ester was ea
Autor:
Yutaka Higashi, Ryoko Yumoto, Noboru Yata, Teruo Murakami, Sadayuki Shigeki, Makiko Yoshioka, Yoshikazu Ikuta
Publikováno v:
Journal of Pharmacy and Pharmacology. 50:49-54
Topical delivery of tranilast (N-(3,4-dimethoxycinnamoyl)anthranic acid), an inhibitor of collagen synthesis and a therapeutic drug for keloid and hypertrophic scar, was examined, in rats, with oleic acid alone or a combination of oleic acid and prop
Publikováno v:
Biological and Pharmaceutical Bulletin. 20:392-396
The first-pass metabolism in the intestine and liver of ONO-5046 (N-[2-[4-(2,2-dimethylpropionyloxy)-phenylsulfonylamino]benz oyl]aminoacetic acid), a newly synthesized elastase inhibitor, was separately estimated in rats. When ONO-5046 solution was
Publikováno v:
Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery. 31:151-158
The feasibility of iontophoretic transdermal delivery of tranilast (N-(3,4-dimethoxycinnamoyl) anthranilic acid) for the treatment of keloid and hypertrophic scars was evaluated in hairless rats and humans. A drug electrode containing tranilast 1.5 m