Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Noboru Takami"'
Autor:
Noboru Takami, Naomi Geshi, Ryuji Inoue, Shinichi Takahashi, Akira Honda, Hai Lin, Yasuhiro Kawarabayashi, Yasuo Mori, Masayuki X. Mori
Publikováno v:
The Journal of Physiology. 586:4209-4223
We investigated the inhibitory role of the nitric oxide (NO)–cGMP–protein kinase G (PKG) pathway on receptor-activated TRPC6 channels in both a heterologous expression system (HEK293 cells) and A7r5 vascular myocytes. Cationic currents due to TRP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3111034cbebf41788f7065553548306a
https://doi.org/10.1113/jphysiol.2008.156083
https://doi.org/10.1113/jphysiol.2008.156083
Recombinant Human Monoclonal IgA Antibody Against CEA to Recruit Neutrophils to CEA-Expressing Cells
Autor:
Lin Wang, Tetsushi Kinugasa, Noboru Takami, Qun Huo, Toshihiro Tanaka, Masahide Kuroki, Motomu Kuroki, Jun Zhao, Hirotomo Shibaguchi
Publikováno v:
Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics. 17:217-222
IgA is able to trigger antibody-dependent cellular cytotoxicity (ADCC) by recruiting neutrophils expressing the Fc receptor for the CHalpha chain. We herein describe the preparation of a human recombinant anti-CEA IgA antibody to kill carcinoembryoni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2936afd5a85bbc772a75271a1e0021b
https://doi.org/10.3727/096504008786111374
https://doi.org/10.3727/096504008786111374
Autor:
Noboru Takami, Tomomi Furuya, H. Michael Ellerby, Kunihiko Murata, Taira Kiyota, Dale E. Bredesen, Sannamu Lee, Gohsuke Sugihara, Yasuro Niidome
Publikováno v:
Journal of Biological Chemistry. 276:41224-41228
Cellular organelles, such as the Golgi apparatus and the endoplasmic reticulum, adopt characteristic structures depending on their function. While the tubular shapes of these structures result from complex protein-lipid interactions that are not full
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25849dcae25536a84d49b6a7318f8ad4
https://doi.org/10.1074/jbc.m104705200
https://doi.org/10.1074/jbc.m104705200
Publikováno v:
Journal of Biological Chemistry. 273:3068-3075
We have investigated the effect of nordihydroguaiaretic acid (NDGA), an inhibitor of lipoxygenase, on the intracellular protein transport and the structure of the Golgi complex. Pulse-chase experiments and immunoelectron microscopy showed that NDGA s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2015671b70f1d4ccda1b35210f7f9a83
https://doi.org/10.1074/jbc.273.5.3068
https://doi.org/10.1074/jbc.273.5.3068
Publikováno v:
Biochemical Journal. 325:455-463
The synaptic vesicle exocytosis occurs by a highly regulated mechanism: syntaxin and 25 kDa synaptosome-associated protein (SNAP-25) are assembled with vesicle-associated membrane protein (VAMP) to form a synaptic core complex and then synaptotagmin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3e54669a5a23967c932ba02d6c63d7d
https://doi.org/10.1042/bj3250455
https://doi.org/10.1042/bj3250455
Publikováno v:
Journal of Biochemistry. 121:862-867
alpha-Elastin with an average molecular mass of 70 kDa, an oxalic acid fragmentation product of highly purified insoluble elastin, induced the migration of macrophages, with maximum activity at 10(-1) microg/ml. Relative to the positive control of 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd52fc792643182f8606f48b11a675ba
https://doi.org/10.1093/oxfordjournals.jbchem.a021666
https://doi.org/10.1093/oxfordjournals.jbchem.a021666
Autor:
Shigenori Ogata, Yoshio Misumi, Noboru Takami, Emiko Tsuji, Yukio Ikehara, Toshiyuki Fujiwara
Publikováno v:
Biochemistry. 31:11921-11927
Dipeptidyl peptidase IV (DPPIV), a serine protease expressed on the cell surface, is deficient in a Fischer rat substrain. Northern blot analysis showed no difference in the size and amount of DPPIV mRNA between normal (344/NC) and deficient (344/CRJ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be78e0132a7e0dbf047c566c86db1509
https://doi.org/10.1021/bi00162a035
https://doi.org/10.1021/bi00162a035
Publikováno v:
Journal of Biological Chemistry. 267:1042-1047
Alkaline phosphatase is anchored to the membrane via glycosylphosphatidylinositol (GPI). Mannose residues of the GPI glycan are suggested to be derived from dolichol-P-mannose. In the present study we examined the effect of 2-fluoro-2-deoxy-D-glucose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba768558eadeeded487ae0757c791bc2
https://doi.org/10.1016/s0021-9258(18)48392-5
https://doi.org/10.1016/s0021-9258(18)48392-5
Autor:
Masaharu Ikeda, Noboru Takami, Miwa Sohda, Yoshio Misumi, Emiko Tsuji, Yukio Ikehara, Kimimitsu Oda
Publikováno v:
Biochemical and Biophysical Research Communications. 179:1181-1186
Summary When expressed in COS cells, human prorenin was secreted into the medium without being processed to an active renin. Co-expression of furin, a mammalian homologue of the yeast KEX2 gene product, did not affect proteolytic processing of proren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6eb20c6024ca4943c2694ff0e41f978
https://doi.org/10.1016/0006-291x(91)91696-a
https://doi.org/10.1016/0006-291x(91)91696-a
Publikováno v:
Biochemical Journal. 276:337-342
A cDNA clone (lambda MC-2) for contrapsin, a serine-proteinase inhibitor, was isolated from a lambda ZAP mouse liver cDNA library. The 1.6 kb cDNA insert of lambda MC-2 contained an open reading frame that encodes a 418-residue polypeptide (46,970 Da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5859be5722f6c1acd0b4bd99c69caafc
https://doi.org/10.1042/bj2760337
https://doi.org/10.1042/bj2760337