Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Noboru Sasagawa"'
Autor:
Satoko Oyama, Hidekuni Yamakawa, Noboru Sasagawa, Yoshio Hosoi, Eugene Futai, Shoichi Ishiura
Publikováno v:
PLoS ONE, Vol 4, Iss 1, p e4199 (2009)
DTNBP1 has been recognized as a schizophrenia susceptible gene, and its protein product, dysbindin-1, is down-regulated in the brains of schizophrenic patients. However, little is known about the physiological role of dysbindin-1 in the central nervo
Externí odkaz:
https://doaj.org/article/d38aa2de39984636b4312f77605fd105
Publikováno v:
International Journal of Biological Sciences, Vol 7, Iss 3, Pp 301-307 (2011)
Various vaccine therapies for Alzheimer's disease (AD) have been investigated. Here we report transgenic rice expressing amyloid β-peptide (Aβ). The Aβ42 gene fused with a green fluorescent protein gene was introduced into rice using the Agrobacte
Externí odkaz:
https://doaj.org/article/c3899d17a3184d9ab5a4a0047f68f2da
Autor:
Noboru Sasagawa
Agarose gel electrophoresis is one of the most fundamental experiment in biochemistry and/or molecular biology, especially in analyzing deoxyribonucleic acid (DNA) or ribonucleic acid (RNA). Many laboratories do agarose gel electrophoresis almost eve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d494a9b1623e8ae18303f3b3c33df5c
https://doi.org/10.5772/intechopen.93439
https://doi.org/10.5772/intechopen.93439
Autor:
Noboru Sasagawa
Publikováno v:
BioScience Trends. 12:627-629
A novel protocol to reuse agarose following agarose gel electrophoresis was established in this study. By repeated freeze-and-thaw of the agarose gel, ethidium bromide and other buffer components in the gel were safely removed from the gel without ge
Autor:
Noboru Sasagawa1 noboru.sasagawa@tokai-u.jp, Michinori Koebis2, Yoji Yonemura2, Hiroaki Mitsuhashi3, Shoichi Ishiura2
Publikováno v:
BioScience Trends. Dec2013, Vol. 7 Issue 6, p270-275. 6p.
Autor:
Shoichi Ishiura, Ichizo Nishino, Michinori Koebis, Yoshihiro Kino, Noboru Sasagawa, Natsumi Ohsawa
Publikováno v:
Genes to Cells. 16:961-972
Myotonic dystrophy type 1 (DM1) is a multisystemic disease caused by a CTG repeat expansion in the 3′-UTR of dystrophia myotonica-protein kinase. Aberrant regulation of alternative splicing is a characteristic feature of DM. Dozens of genes have be
Autor:
Eugene Futai, Taiji Yoshida, Jun Nojima, Noboru Sasagawa, Shoichi Ishiura, Yuichiro Watanabe, Rika Ishii-Katsuno
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 75:396-400
The main signs of Alzheimer's disease (AD) are cognitive impairment and senile plaques composed of amyloid beta (Aβ) observed in patients' brains. Therefore, therapy for AD focuses on the removal of Aβ. We developed an "edible vaccine" that employs
Autor:
Chika Washizu, Noboru Sasagawa, Shoichi Ishiura, Nobuyuki Nukina, Yuriko Nezu, Hayato Onishi, Yoshihiro Kino, Yoko Oma
Publikováno v:
Nucleic Acids Research
The expression and function of the skeletal muscle chloride channel CLCN1/ClC-1 is regulated by alternative splicing. Inclusion of the CLCN1 exon 7A is aberrantly elevated in myotonic dystrophy (DM), a genetic disorder caused by the expansion of a CT
Publikováno v:
Journal of Neuroscience Research. 87:1090-1097
The genome of the nematode Caenorhabditis elegans possesses an orthologous sequence to the Drosophila muscleblind (mbl) and mammalian muscleblind-like genes (MBNLs). This ortholog, K02H8.1, which has a high degree of homology (about 50%) to human MBN
Autor:
Ichizo Nishino, Yukiko K. Hayashi, Hiroaki Mitsuhashi, Shoichi Ishiura, Eugene Futai, Noboru Sasagawa
Publikováno v:
Journal of Neurochemistry. 105:101-112
SHPS-1 is an immunoglobulin superfamily protein with four immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in its cytoplasmic region. Various neurotrophic factors induce the tyrosine phosphorylation of SHPS-1 and the association of SHPS-1 with