Zobrazeno 1 - 10
of 185
pro vyhledávání: '"Noboru Okamura"'
Publikováno v:
BMC Geriatrics, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background Once older persons become frail, the risk of falls, bone fractures, and other problems increases. Exercise intervention is a form of prevention that has a high degree of evidence. Objective We investigated the effectiveness of fra
Externí odkaz:
https://doaj.org/article/f4df977395794ce7ba792d431a64c8f9
Publikováno v:
Brain and Behavior, Vol 10, Iss 12, Pp n/a-n/a (2020)
Abstract Introduction 15‐deoxy‐Δ12,14‐prostaglandin J2 (15d‐PGJ2) causes neuronal apoptosis independently of its nuclear receptor, peroxysome‐proliferator activated receptor γ. Its membrane receptor, chemoattractant receptor‐homologous
Externí odkaz:
https://doaj.org/article/96ddf63fc2fb41e4a42d5952dd3ef49a
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 36, Iss 1, Pp 1-9 (2017)
Abstract Background Troglitazone (TGZ) is a peroxisome proliferator-activated receptor gamma (PPARγ) agonist that has been investigated as a potential chemopreventive and chemotherapeutic agent. However, the antitumor efficacy and mechanisms of TGZ
Externí odkaz:
https://doaj.org/article/5829611b354742acb8e521130ce10f76
Publikováno v:
Xenobiotica. 52:608-612
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4bc530e8cc16f464efbad4c938865551
https://doi.org/10.1080/00498254.2022.2118643
https://doi.org/10.1080/00498254.2022.2118643
Publikováno v:
Biological and Pharmaceutical Bulletin. 45:276-283
Lung cancer is the leading cause of cancer-related deaths worldwide. Troglitazone (TGZ), a peroxisome proliferator-activated receptor gamma (PPARγ) ligand, is a potential antitumor agent. However, the action mechanism of TGZ in lung adenocarcinoma c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::347f8265022fa0823dc6b114a796f1e7
https://doi.org/10.1248/bpb.b21-00785
https://doi.org/10.1248/bpb.b21-00785
Publikováno v:
Biological and Pharmaceutical Bulletin. 44:1878-1885
Renal cell carcinoma (RCC) is the most common type of kidney cancer. Given that stage IV RCC is intractable, there is a need for a novel treatment strategy. We investigated the antitumor effects of telmisartan (TEL) and their underlying mechanisms in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1110781c21954f76fb61d0f7f3bb52f7
https://doi.org/10.1248/bpb.b21-00654
https://doi.org/10.1248/bpb.b21-00654
Telmisartan Exerts Cytotoxicity in Scirrhous Gastric Cancer Cells by Inducing G0/G1Cell Cycle Arrest
Autor:
Noboru Okamura, Yoshie Tsujiya, Motohiro Yamamori, Masakazu Yashiro, Yurie Yamamoto, Ai Hasegawa
Publikováno v:
Anticancer Research. 41:5461-5468
BACKGROUND/AIM This study aimed to assess the effects of telmisartan (TEL), a potential antitumor agent, and its mechanism of action in the regulation of apoptosis, autophagy, and cell cycle in scirrhous gastric cancer (SGC). MATERIALS AND METHODS Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2052b2ecf57881e6da92fd92dc00a74
https://doi.org/10.21873/anticanres.15358
https://doi.org/10.21873/anticanres.15358
Autor:
Noritake Hirota, Noboru Okamura
Publikováno v:
Integrated Pharmacy Research and Practice. 9:243-256
Purpose Despite the formal establishment of the Health Support Pharmacy system, few community pharmacies have transitioned to this new designation in Japan. Moreover, patients' perspectives on the usefulness of health-support pharmacies and community
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ed59df5ed9f13e770a488466ef4bb20
https://doi.org/10.2147/iprp.s275288
https://doi.org/10.2147/iprp.s275288
Autor:
Noritake Hirota, Noboru Okamura
Publikováno v:
Pharmacology & Pharmacy. 11:55-70
A questionnaire survey was conducted employing pharmacists at 350 Japanese Federation of Democratic Medical Institutions (Min-Iren) member pharmacies, evaluating the challenges related to registering as a Health Support Pharmacy (HSP). Completed resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3c319daddf428b58950d5dfee070787
https://doi.org/10.4236/pp.2020.114006
https://doi.org/10.4236/pp.2020.114006
Publikováno v:
International Journal of Medical Sciences, Vol 9, Iss 7, Pp 555-566 (2012)
Introduction: Agonists of peroxisome proliferator-activated receptor gamma (PPARγ) have been examined as chemopreventive and chemotherapeutic agents. The aim was to investigate the cytotoxicity and action mechanisms of 15-deoxy-Δ12,14-prostaglandin
Externí odkaz:
https://doaj.org/article/69cdd93bd651476d9bfe5a8a8a8303a5