Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Noboru, Kawabe"'
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0230375 (2020)
Cathepsins are the major lysosomal proteases that maintain intracellular homeostasis. Herein, we investigated the alterations in myocardial cathepsin expression during aging, cardiac hypertrophy, and sudden cardiac death (SCD). Cardiac tissue and blo
Externí odkaz:
https://doaj.org/article/cfde5d56e0404e4eaaa0adb5c8b4a495
Autor:
Takamasa Ishii, Masaki Miyazawa, Yumi Takanashi, Maya Tanigawa, Kayo Yasuda, Hiromi Onouchi, Noboru Kawabe, Junji Mitsushita, Phil S. Hartman, Naoaki Ishii
Publikováno v:
Redox Biology, Vol 2, Iss C, Pp 679-685 (2014)
Historical data in the 1950s suggests that 7%, 11%, 33%, and 87% of couples were infertile by ages 30, 35, 40 and 45, respectively. Up to 22.3% of infertile couples have unexplained infertility. Oxidative stress is associated with male and female inf
Externí odkaz:
https://doaj.org/article/086130bfc5bc432ea41d512314232602
Autor:
Chisa Okada, Ayumi Sasaki, Yu Kakimoto, Hideo Tsukamoto, Ryoko Nagao, Noboru Kawabe, Motoki Osawa
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Scientific Reports
Scientific Reports
Lipofuscin is an intracellular aggregate of highly oxidized proteins that cannot be digested in the ubiquitin-proteasome system and accumulate mainly in lysosomes, especially in aged cells and pathological conditions. However, no systematic study has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc723c39c407782a38893d9c3262c74f
http://link.springer.com/article/10.1038/s41598-019-40250-0
http://link.springer.com/article/10.1038/s41598-019-40250-0
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 3, p e0230375 (2020)
PLoS ONE, Vol 15, Iss 3, p e0230375 (2020)
Cathepsins are the major lysosomal proteases that maintain intracellular homeostasis. Herein, we investigated the alterations in myocardial cathepsin expression during aging, cardiac hypertrophy, and sudden cardiac death (SCD). Cardiac tissue and blo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dea3b4370019fb884469ae70fa42b8ab
http://europepmc.org/articles/PMC7075574
http://europepmc.org/articles/PMC7075574
Autor:
Shunya Takizawa, Masato Hoshino, Akemi Kamijo, Masato Ohtsuka, Noboru Kawabe, Rino Saiga, Katsuko Naitou, Akihisa Takeuchi, Kentaro Uesugi, Ryuta Mizutani
Publikováno v:
Journal of Comparative Neurology. 527:2091-2100
Multiple sclerosis is a neurological disorder in which the myelin sheaths of axons are damaged by the immune response. We report here a three-dimensional structural analysis of brain and spinal cord tissues of a mouse model of multiple sclerosis, kno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::571939dd6f58d32e437443638ec4136f
https://doi.org/10.1002/cne.24544
https://doi.org/10.1002/cne.24544
Autor:
Shigetaka Kanda, Sachie Tanaka, Sadaki Inokuchi, Mari Amino, Tadashi Hashida, Hiroyuki Kurosawa, Keisuke Uchida, Yuji Ikari, Shinobu Oshikiri, Koichiro Yoshioka, Noboru Kawabe
Publikováno v:
Pacing and Clinical Electrophysiology. 40:1103-1112
Background Iodine-123 metaiodobenzylguanidine (123 I-MIBG) is useful for detecting sympathetic innervation in the heart, and has been closely associated with fatal arrhythmias. However, such imaging is typically calibrated to the area of highest upta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1c839784793f58679ad3d8adc54c9e6
https://doi.org/10.1111/pace.13174
https://doi.org/10.1111/pace.13174
Autor:
Sachie Tanaka, Sadaki Inokuchi, Mari Amino, Teruyo Tsukada, Teruhisa Tanabe, Koichiro Yoshioka, Masako Izumi, Yuji Ikari, Tadashi Hashida, Noboru Kawabe, Yoshiya Furusawa
Publikováno v:
Pacing and Clinical Electrophysiology. 40:379-390
BACKGROUND Targeted external heavy ion irradiation (THIR) of rabbit hearts 2 weeks after myocardial infarction (MI) reduced the vulnerability of fatal ventricular tachyarrhythmias (VT/VF) in association with the increased connexin43 (Cx43). Increased
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26d09f3363d2c713707bb4c599b26863
https://doi.org/10.1111/pace.13031
https://doi.org/10.1111/pace.13031
Autor:
Naoto Fukuyama, Hidezo Mori, Yuko Tsukamoto, Yoshiro Shinozaki, Etsuro Tanaka, Keiji Umetani, Yoshimori Ikeya, Sayato Fukui, Noriaki Wakana, Shunya Takizawa, Toshiharu Fujii, Yoko Takahari, Kikue Todoroki, Chiharu Tanaka, Noboru Kawabe
Publikováno v:
Geriatrics & Gerontology International. 15:74-80
Aim As altered blood flow in the cerebral perforating arteries (PA) might be related to development of cerebral white matter hyperintensities, we examined whether the hemodynamic relationship of the PA and middle cerebral artery (MCA) is altered in r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64e7510eae1bc0676c0a3c3d9b19781a
https://doi.org/10.1111/ggi.12658
https://doi.org/10.1111/ggi.12658
Autor:
Yoshitaka Arase, Ting Wang, Shunji Hirose, Yoshinao Kobayashi, Yukihiko Adachi, Tsuneo Kitamura, Hiroshi Sakugawa, Peter N. Robinson, Kota Tsuruya, Masayuki Tanaka, Tatehiro Kagawa, Yoichi Hiasa, Noboru Kawabe, Hideki Hayashi, Tetsuya Mine, Akira Oka, Tomasz Zemojtel, Takashi Shiina, Kazuya Anzai, Koichi Shiraishi, Tadayuki Sato
Publikováno v:
Human Mutation. 36:327-332
Sequences of long-interspersed elements (LINE-1, L1) make up ∼17% of the human genome. De novo insertions of retrotransposition-active L1s can result in genetic diseases. It has been recently shown that the homozygous inactivation of two adjacent g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29b6984b35b18d0a11b9d60ce8a08305
https://doi.org/10.1002/humu.22745
https://doi.org/10.1002/humu.22745
Autor:
Mari, Amino, Koichiro, Yoshioka, Sachie, Tanaka, Noboru, Kawabe, Hiroyuki, Kurosawa, Keisuke, Uchida, Shinobu, Oshikiri, Tadashi, Hashida, Shigetaka, Kanda, Sadaki, Inokuchi, Yuji, Ikari
Publikováno v:
Pacing and clinical electrophysiology : PACE. 40(10)
Iodine-123 metaiodobenzylguanidine (Twenty New Zealand white rabbits treated with phenol or sham were prepared under anesthesia. Sympathetic innervation was quantified using autoradiography and immunostaining 4 weeks after phenol application, and ele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6e401515e1d7d842eac9ab4afe295d5e
https://pubmed.ncbi.nlm.nih.gov/28857212
https://pubmed.ncbi.nlm.nih.gov/28857212