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Embryonic rat dorsal root ganglia organotypic culture: a reliable model to test neurotoxicity

Autor: NICOLINI, GABRIELLA, MAGGIONI, DANIELE, TREDICI, GIOVANNI, CAVALETTI, GUIDO ANGELO, Nobbio, L, Schenone, A

Neurotoxicity is a common dose-limiting side-effect of several drugs. So far a validated test method to screen drugs neurotoxicity does not exist, therefore in this interdepartment study we have analyzed the effectiveness of a neurotoxicty assessment

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1299::472dffb4caf59826bc9a4979cf77350e
http://hdl.handle.net/10281/60787

Is overwork weakness relevant in Charcot-Marie-Tooth disease?

Autor: Piscosquito, G., Reilly, M. M., Schenone, A., Fabrizi, G. M., Cavallaro, T., Santoro, L., Vita, G., Quattrone, A., Padua, L., Gemignani, F., Visioli, F., Laura, M., Calabrese, D., Hughes, R. A. C., Radice, D., Solari, A., Pareyson, D., Marchesi, C., Salsano, E., Nanetti, L., Marelli, C., Scaioli, V., Ciano, C., Rimoldi, M., Lauria, G., Rizzetto, E., Camozzi, F., Narciso, E., Grandis, M., Monti Bragadin, M., Nobbio, L., Casano, A., Bertolasi, L., Cabrini, I., Corra, K., Rizzuto, N., Manganelli, F., Pisciotta, C., Nolano, M., Mazzeo, A., Di Leo, R., Majorana, G., Russo, M., Valentino, P., Nistico, R., Pirritano, D., Lucisano, A., Canino, M., Pazzaglia, C., Granata, G., Foschini, M., Brindani, F., Vitetta, F., Allegri, I., Bogani, P., Blake, J., Koltzenburg, M., Hutton, E., Lunn, M.

Publikováno v: Journal of neurology, neurosurgery and psychiatry 85 (2014): 1354–1358. doi:10.1136/jnnp-2014-307598
info:cnr-pdr/source/autori:Piscosquito, G.; Reilly, M. M.; Schenone, A.; Fabrizi, G. M.; Cavallaro, T.; Santoro, L.; Vita, G.; Quattrone, A.; Padua, L.; Gemignani, F.; Visioli, F.; Laura, M.; Calabrese, D.; Hughes, R. A. C.; Radice, D.; Solari, A.; Pareyson, D./titolo:Is overwork weakness relevant in Charcot-Marie-Tooth disease?/doi:10.1136%2Fjnnp-2014-307598/rivista:Journal of neurology, neurosurgery and psychiatry/anno:2014/pagina_da:1354/pagina_a:1358/intervallo_pagine:1354–1358/volume:85

BACKGROUND: In overwork weakness (OW), muscles are increasingly weakened by exercise, work or daily activities. Although it is a well-established phenomenon in several neuromuscular disorders, it is debated whether it occurs in Charcot-Marie-Tooth di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::791650ad373c6bda27362c42191e7531

Selected items from the Charcot-Marie-Tooth (CMT) Neuropathy Score and secondary clinical outcome measures serve as sensitive clinical markers of disease severity in CMT1A patients

Autor: Mannil, M., Solari, A., Leha, A., Pelayo-Negro, A. L., Berciano, J., Schlotter-Weigel, B., Walter, M. C., Rautenstrauss, B., Schnizer, T. J., Schenone, A., Seeman, P., Kadian, C., Schreiber, O., Angarita, N. G., Fabrizi, G. M., Gemignani, F., Padua, L., Santoro, L., Quattrone, A., Vita, G., Calabrese, D., Marchesi, C., Salsano, E., Nanetti, L., Marelli, C., Scaioli, V., Ciano, C., Rimoldi, M., Lauria, G., Rizzetto, E., Camozzi, F., Narciso, E., Grandis, M., Monti-Bragadin, M., Nobbio, L., Cavallaro, T., Casano, A., Bertolasi, L., Cabrini, I., Corra, K., Manganelli, F., Pisciotta, C., Nolano, M., Mazzeo, A., Aguennouz, M., Di Leo, R., Majorana, G., Lanzano, N., Valenti, F., Valentino, P., Nistico, R., Pirritano, D., Lucisano, A., Canino, M., Pazzaglia, C., Granata, G., Foschini, M., Brindani, F., Vitetta, F., Allegri, I., Visioli, F., Bogani, P., Blake, J., Koltzenburg, M., Hutton, E., Lunn, M., Young, P., Laura, M., Haberlova, J., Mazanec, R., Paulus, W., Beissbarth, T., Shy, M. E., Reilly, M. M., Pareyson, D., Sereda, M. W.

Publikováno v: Neuromuscular disorders 24 (2014): 1003–1017. doi:10.1016/j.nmd.2014.06.431
info:cnr-pdr/source/autori:Mannil, Manoj; Solari, Alessandra; Leha, Andreas; Pelayo-Negro, Ana L.; Berciano, Jose; Schlotter-Weigel, Beate; Walter, Maggie C.; Rautenstrauss, Bernd; Schnizer, Tuuli J.; Schenone, Angelo; Seeman, Pavel; Kadian, Chandini; Schreiber, Olivia; Angarita, Natalia G.; Fabrizi, Gian Maria; Gemignani, Franco; Padua, Luca; Santoro, Lucio; Quattrone, Aldo; Vita, Giuseppe; Calabrese, Daniela; Young, Peter; Laura, Matilde; Haberlova, Jana; Mazanec, Radim; Paulus, Walter; Beissbarth, Tim; Shy, Michael E.; Reilly, Mary M.; Pareyson, Davide; Sereda, Michael W./titolo:Selected items from the Charcot-Marie-Tooth (CMT) Neuropathy Score and secondary clinical outcome measures serve as sensitive clinical markers of disease severity in CMT1A patients/doi:10.1016%2Fj.nmd.2014.06.431/rivista:Neuromuscular disorders/anno:2014/pagina_da:1003/pagina_a:1017/intervallo_pagine:1003–1017/volume:24

This study evaluates primary and secondary clinical outcome measures in Charcot-Marie-Tooth disease type 1A (CMT1A) with regard to their contribution towards discrimination of disease severity. The nine components of the composite Charcot-Marie-Tooth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeda0250e6c2131c9873e1f957a473d4
http://hdl.handle.net/10807/62378