Zobrazeno 1 - 10
of 244
pro vyhledávání: '"Noah Weisleder"'
Autor:
Joaquin Muriel, Valeriy Lukyanenko, Thomas A. Kwiatkowski, Yi Li, Sayak Bhattacharya, Kassidy K. Banford, Daniel Garman, Hannah R. Bulgart, Roger B. Sutton, Noah Weisleder, Robert J. Bloch
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 2, Pp 101257- (2024)
Mutations in the DYSF gene, encoding the protein dysferlin, lead to several forms of muscular dystrophy. In healthy skeletal muscle, dysferlin concentrates in the transverse tubules and is involved in repairing the sarcolemma and stabilizing Ca2+ sig
Externí odkaz:
https://doaj.org/article/a94b4fbba8b74fb29787af068191750d
Autor:
Joe Yasa, Claudia E. Reed, Adam M. Bournazos, Frances J. Evesson, Ignatius Pang, Mark E. Graham, Jesse R. Wark, Brunda Nijagal, Kim H. Kwan, Thomas Kwiatkowski, Rachel Jung, Noah Weisleder, Sandra T. Cooper, Frances A. Lemckert
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-16 (2023)
Abstract Dysferlin is a Ca2+-activated lipid binding protein implicated in muscle membrane repair. Recessive variants in DYSF result in dysferlinopathy, a progressive muscular dystrophy. We showed previously that calpain cleavage within a motif encod
Externí odkaz:
https://doaj.org/article/6b549e68706942818cd58183122bbf7a
Publikováno v:
Cells, Vol 12, Iss 12, p 1660 (2023)
Plasma membrane repair is an essential cellular mechanism that reseals membrane disruptions after a variety of insults, and compromised repair capacity can contribute to the progression of many diseases. Neurodegenerative diseases are marked by membr
Externí odkaz:
https://doaj.org/article/616d390bebf04cc88f533ae0900bfa21
Autor:
Océane Ballouhey, Marie Chapoton, Benedicte Alary, Sébastien Courrier, Nathalie Da Silva, Martin Krahn, Nicolas Lévy, Noah Weisleder, Marc Bartoli
Publikováno v:
Biomedicines, Vol 11, Iss 5, p 1438 (2023)
Dysferlinopathies are a group of autosomal recessive muscular dystrophies caused by pathogenic variants in the DYSF gene. While several animal models of dysferlinopathy have been developed, most of them involve major disruptions of the Dysf gene locu
Externí odkaz:
https://doaj.org/article/4d8ca5a89eb94758a09b53f5ef31b19d
Autor:
Ji Young Kim, Josie A. Silvaroli, Gabriela Vasquez Martinez, Bijay Bisunke, Alanys V. Luna Ramirez, Laura A. Jayne, Mei Ji He Ho Feng, Bhavya Girotra, Shirely M. Acosta Martinez, Corynne R. Vermillion, Isaac Z. Karel, Nicholas Ferrell, Noah Weisleder, Sangwoon Chung, John W. Christman, Craig R. Brooks, Sethu M. Madhavan, Kari R. Hoyt, Rachel E. Cianciolo, Anjali A. Satoskar, Diana Zepeda-Orozco, Jennifer C. Sullivan, Alan J. Davidson, Amandeep Bajwa, Navjot Singh Pabla
Publikováno v:
Kidney International. 103:1093-1104
Autor:
Hussam E. Salhi, Vikram Shettigar, Lorien Salyer, Sarah Sturgill, Elizabeth A. Brundage, Joel Robinett, Zhaobin Xu, Eaman Abay, Jeovanna Lowe, Paul M.L. Janssen, Jill A. Rafael-Fortney, Noah Weisleder, Mark T. Ziolo, Brandon J. Biesiadecki
Publikováno v:
Journal of Molecular and Cellular Cardiology. 176:84-96
Autor:
Brian J. Paleo, Kevin E. McElhanon, Hannah R. Bulgart, Kassidy K. Banford, Eric X Beck, Kristina M. Sattler, Briana N. Goines, Shelby L. Ratcliff, Kelly E. Crowe, Noah Weisleder
Publikováno v:
Cells, Vol 11, Iss 9, p 1417 (2022)
Duchenne muscular dystrophy (DMD) is a common X-linked degenerative muscle disorder that involves mutations in the DMD gene that frequently reduce the expression of the dystrophin protein, compromising the structural integrity of the sarcolemmal memb
Externí odkaz:
https://doaj.org/article/9a4592bacceb45fbaf358a3bc2e9eaa7
Autor:
Jihad Aljabban, Saad Syed, Sharjeel Syed, Michael Rohr, Noah Weisleder, Kevin E. McElhanon, Laith Hasan, Laraib Safeer, Kalyn Hoffman, Nabeal Aljabban, Mohamed Mukhtar, Nikhil Adapa, Zahir Allarakhia, Maryam Panahiazar, Isaac Neuhaus, Susan Kim, Dexter Hadley, Wael Jarjour
Publikováno v:
Heliyon, Vol 6, Iss 9, Pp e04866- (2020)
Aims: Dermatomyositis (DM) is a progressive, idiopathic inflammatory myopathy with poorly understood pathogenesis. A hallmark of DM is an increased risk for developing breast, ovarian, and lung cancer. Since autoantibodies against anti-TIF-1-γ, a me
Externí odkaz:
https://doaj.org/article/69b214ceceef4e5489ce1d16e32be58e
Autor:
Brian J Paleo, Kathryn M Madalena, Rohan Mital, Kevin E McElhanon, Thomas A Kwiatkowski, Aubrey L Rose, Jessica K Lerch, Noah Weisleder
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231194 (2020)
Various injuries to the neural tissues can cause irreversible damage to multiple functions of the nervous system ranging from motor control to cognitive function. The limited treatment options available for patients have led to extensive interest in
Externí odkaz:
https://doaj.org/article/c29e3ca517324b0ab49c948ce8e8fd76
Autor:
Kamal Awad, Logan Moore, Jian Huang, Lauren Gomez, Leticia Brotto, Venu Varanasi, Christopher Cardozo, Noah Weisleder, Zui Pan, Jingsong Zhou, Lynda Bonewald, Marco Brotto
Publikováno v:
Tissue Engineering Part C: Methods.