Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Noah W Palm"'
Autor:
Akash Gupta, Gunjan Arora, Connor E Rosen, Zachary Kloos, Yongguo Cao, Jiri Cerny, Andaleeb Sajid, Dieuwertje Hoornstra, Maryna Golovchenko, Natalie Rudenko, Ulrike Munderloh, Joppe W Hovius, Carmen J Booth, Christine Jacobs-Wagner, Noah W Palm, Aaron M Ring, Erol Fikrig
Publikováno v:
PLoS Pathogens, Vol 16, Iss 11, p e1009030 (2020)
Lyme disease, the most common vector-borne illness in North America, is caused by the spirochete Borrelia burgdorferi. Infection begins in the skin following a tick bite and can spread to the hearts, joints, nervous system, and other organs. Diverse
Externí odkaz:
https://doaj.org/article/8aa2ff8b5a8c444497679cc5ca22c95e
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Virulent Klebsiella oxytoca strains are associated with gut and lung pathologies, yet our understanding of the molecular signals governing pathogenesis remains limited. Here, we characterized a family of K. oxytoca pyrazine and pyrazinone au
Externí odkaz:
https://doaj.org/article/3772e4dd2c564d18bdb03c26e23fc41a
Autor:
Ainize Peña-Cearra, Deguang Song, Janire Castelo, Ainhoa Palacios, Jose Luis Lavín, Mikel Azkargorta, Felix Elortza, Miguel Fuertes, Miguel Angel Pascual-Itoiz, Diego Barriales, Itziar Martín-Ruiz, Asier Fullaondo, Ana M. Aransay, Hector Rodríguez, Noah W. Palm, Juan Anguita, Leticia Abecia
Publikováno v:
npj Biofilms and Microbiomes, Vol 9, Iss 1, Pp 1-14 (2023)
Abstract Recent evidence demonstrates potential links between mitochondrial dysfunction and inflammatory bowel diseases (IBD). In addition, bidirectional interactions between the intestinal microbiota and host mitochondria may modulate intestinal inf
Externí odkaz:
https://doaj.org/article/3dff9ee3e3a641b592f1a6aa0abdf433
Autor:
Khyati Girdhar, Yusuf Dogus Dogru, Qian Huang, Yi Yang, Vladimir Tolstikov, Amol Raisingani, Martina Chrudinova, Jaewon Oh, Kristina Kelley, Jonas F. Ludvigsson, Michael A. Kiebish, Noah W. Palm, Johnny Ludvigsson, Emrah Altindis
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-20 (2023)
Abstract Background Celiac disease (CD) is an autoimmune disorder triggered by gluten consumption. Almost all CD patients possess human leukocyte antigen (HLA) DQ2/DQ8 haplotypes; however, only a small subset of individuals carrying these alleles dev
Externí odkaz:
https://doaj.org/article/90ee455b198944da9eb5694319c0b5a9
Autor:
Anna Woestemeier, Pasquale Scognamiglio, Yu Zhao, Jonas Wagner, Franziska Muscate, Christian Casar, Francesco Siracusa, Filippo Cortesi, Theodora Agalioti, Simone Müller, Adrian Sagebiel, Leonie Konczalla, Ramez Wahib, Karl-Frederick Karstens, Anastasios D. Giannou, Anna Duprée, Stefan Wolter, Milagros N. Wong, Anne K. Mühlig, Agata A. Bielecka, Vikas Bansal, Tianran Zhang, Oliver Mann, Victor G. Puelles, Tobias B. Huber, Ansgar W. Lohse, Jakob R. Izbicki, Noah W. Palm, Stefan Bonn, Samuel Huber, Nicola Gagliani
Publikováno v:
JCI Insight, Vol 8, Iss 1 (2023)
A role of CD4+ T cells during the progression from nonalcoholic fatty liver disease (NAFLD) to nonalcoholic steatohepatitis (NASH) has been suggested, but which polarization state of these cells characterizes this progression and the development of f
Externí odkaz:
https://doaj.org/article/bd1ff2fbaac043e9a2e870f55d257c09
Autor:
Yi Yang, Mytien Nguyen, Varnica Khetrapal, Nicole D. Sonnert, Anjelica L. Martin, Haiwei Chen, Martin A. Kriegel, Noah W. Palm
Publikováno v:
Nature
Gut commensals with the capacity to translocate across the intestinal barrier can drive the development of diverse immune-mediated diseases(1–4). However, the key factors that dictate bacterial translocation remain unclear. Recent studies have reve
Autor:
Mytien Nguyen, Noah W. Palm
Publikováno v:
Seminars in Immunopathology. 44:569-579
In the past two decades, work on the microbiota-gut-brain axis has led to a renewed appreciation for the interconnectedness between body systems in both clinical and scientific circles. In the USA alone, millions of adults are burdened with non-commu
Publikováno v:
International Journal of Systematic and Evolutionary Microbiology. 73
As part of a culturomics study to identify bacterial species associated with inflammatory bowel disease, a large collection of bacteria was isolated from patients with ulcerative colitis. Two of these isolates were tentatively identified as members o
Autor:
Yiyun Cao, Joonseok Oh, Mengzhao Xue, Won Jae Huh, Jiawei Wang, Jaime A. Gonzalez-Hernandez, Tyler A. Rice, Anjelica L. Martin, Deguang Song, Jason M. Crawford, Seth B. Herzon, Noah W. Palm
Publikováno v:
Science. 378
Microbiota-derived metabolites that elicit DNA damage can contribute to colorectal cancer (CRC). However, the full spectrum of genotoxic chemicals produced by indigenous gut microbes remains to be defined. We established a pipeline to systematically
Autor:
Gunjan Arora, Geoffrey E. Lynn, Xiaotian Tang, Connor E. Rosen, Dieuwertje Hoornstra, Andaleeb Sajid, Joppe W. Hovius, Noah W. Palm, Aaron M. Ring, Erol Fikrig
Publikováno v:
mBio, 13(5). American Society for Microbiology
Relapsing fever, caused by diverse Borrelia spirochetes, is prevalent in many parts of the world and causes significant morbidity and mortality. To investigate the pathoetiology of relapsing fever, we performed a high-throughput screen of Borrelia-bi