Zobrazeno 1 - 2
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pro vyhledávání: '"Noah R. Beratan"'
Autor:
Shivesh Ghura, Noah R. Beratan, Xinglong Shi, Elena Alvarez-Periel, Sarah E. Bond Newton, Cagla Akay-Espinoza, Kelly L. Jordan-Sciutto
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Common single-nucleotide variants (SNVs) of eukaryotic translation initiation factor 2 alpha kinase 3 (EIF2AK3) slightly increase the risk of disorders in the periphery and the central nervous system. EIF2AK3 encodes protein kinase RNA-like
Externí odkaz:
https://doaj.org/article/cd849f67507748ea9342ece45a821b3e
PERK is a transmembrane kinase located on the ER with a luminal domain that senses ER stresses, such as protein misfolding, and a cytosolic kinase domain. Upon stress sensing, PERK activates and phosphorylates eIF2α to attenuate global translation w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f390c8ce59a88099c87abda49aa04ec
https://doi.org/10.1101/2022.09.02.506340
https://doi.org/10.1101/2022.09.02.506340
