Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Noah P. Bradley"'
Publikováno v:
mBio, Vol 13, Iss 2 (2022)
ABSTRACT Unique DNA repair enzymes that provide self-resistance against therapeutically important, genotoxic natural products have been discovered in bacterial biosynthetic gene clusters (BGCs). Among these, the DNA glycosylase AlkZ is essential for
Externí odkaz:
https://doaj.org/article/126f1824657d4beb85520a46835653cb
Autor:
Xiaorong Chen, Noah P Bradley, Wei Lu, Katherine L Wahl, Mei Zhang, Hua Yuan, Xian-Feng Hou, Brandt F Eichman, Gong-Li Tang
Publikováno v:
Nucleic Acids Research. 50:2417-2430
Two families of DNA glycosylases (YtkR2/AlkD, AlkZ/YcaQ) have been found to remove bulky and crosslinking DNA adducts produced by bacterial natural products. Whether DNA glycosylases eliminate other types of damage formed by structurally diverse anti
Publikováno v:
Trends Biochem Sci
The base excision repair (BER) pathway historically has been associated with maintaining genome integrity by eliminating nucleobases with small chemical modifications. In the past several years, however, BER was found to play additional roles in geno
Autor:
Noah P, Bradley, Lauren A, Washburn, Plamen P, Christov, Coran M H, Watanabe, Brandt F, Eichman
Publikováno v:
Nucleic Acids Research
Interstrand DNA crosslinks (ICLs) are a toxic form of DNA damage that block DNA replication and transcription by tethering the opposing strands of DNA. ICL repair requires unhooking of the tethered strands by either nuclease incision of the DNA backb
Autor:
Lauren A Washburn, Plamen P. Christov, Noah P. Bradley, Coran M. H. Watanabe, Brandt F. Eichman
Publikováno v:
Nucleic Acids Research.
Interstrand DNA crosslinks (ICLs) are a toxic form of DNA damage that block DNA replication and transcription by tethering the opposing strands of DNA. ICL repair requires unhooking of the tethered strands by either nuclease incision of the DNA backb
Autor:
Diego Libkind, Amanda Beth Hulfachor, Xing-Xing Shen, Chris Todd Hittinger, Jacob L. Steenwyk, Dana A. Opulente, Noah P. Bradley, Cletus P. Kurtzman, Abigail L. LaBella, Jacek Kominek, Neža Čadež, Jeremy DeVirgilio, Brandt F. Eichman, Xiaofan Zhou, Antonis Rokas
Cell cycle checkpoints and DNA repair processes protect organisms from potentially lethal mutational damage. Compared to other budding yeasts in the subphylum Saccharomycotina, we noticed that a lineage in the genus Hanseniaspora exhibited very high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b19e16fe89e11105c4bb901cd58edf4
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 114(17)
DNA glycosylases are important editing enzymes that protect genomic stability by excising chemically modified nucleobases that alter normal DNA metabolism. These enzymes have been known only to initiate base excision repair of small adducts by extrus
Autor:
Chris Todd Hittinger, Noah P. Bradley, Cletus P. Kurtzman, Diego Libkind, Abigail L. LaBella, Xing-Xing Shen, Jacek Kominek, Antonis Rokas, Jacob L. Steenwyk, Amanda Beth Hulfachor, Brandt F. Eichman, Jeremy DeVirgilio, Xiaofan Zhou, Neža Čadež, Dana A. Opulente
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS Biology, Vol 17, Iss 5, p e3000255 (2019)
PLoS Biology
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS Biology, Vol 17, Iss 5, p e3000255 (2019)
PLoS Biology
Cell-cycle checkpoints and DNA repair processes protect organisms from potentially lethal mutational damage. Compared to other budding yeasts in the subphylum Saccharomycotina, we noticed that a lineage in the genus Hanseniaspora exhibited very high
Autor:
Jacob L Steenwyk, Dana A Opulente, Jacek Kominek, Xing-Xing Shen, Xiaofan Zhou, Abigail L Labella, Noah P Bradley, Brandt F Eichman, Neža Čadež, Diego Libkind, Jeremy DeVirgilio, Amanda Beth Hulfachor, Cletus P Kurtzman, Chris Todd Hittinger, Antonis Rokas
Publikováno v:
PLoS Biology, Vol 17, Iss 5, p e3000255 (2019)
Cell-cycle checkpoints and DNA repair processes protect organisms from potentially lethal mutational damage. Compared to other budding yeasts in the subphylum Saccharomycotina, we noticed that a lineage in the genus Hanseniaspora exhibited very high
Externí odkaz:
https://doaj.org/article/0b7c92d4715341e293a69ee03ae77cef