Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Noah Moruzzi"'
Autor:
Francesca Lazzeri-Barcelo, Nuria Oliva-Vilarnau, Marion Baniol, Barbara Leibiger, Olaf Bergmann, Volker M. Lauschke, Ingo B. Leibiger, Noah Moruzzi, Per-Olof Berggren
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Longitudinal monitoring of liver function in vivo is hindered by the lack of high-resolution non-invasive imaging techniques. Using the anterior chamber of the mouse eye as a transplantation site, we have established a platform for longitudi
Externí odkaz:
https://doaj.org/article/2eda5aaab39e4b1b93164e67176e1475
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/057807f5f09f4d95bbec1894044b6223
Autor:
Pierre Sabatier, Christian M. Beusch, Amir A. Saei, Mike Aoun, Noah Moruzzi, Ana Coelho, Niels Leijten, Magnus Nordenskjöld, Patrick Micke, Diana Maltseva, Alexander G. Tonevitsky, Vincent Millischer, J. Carlos Villaescusa, Sandeep Kadekar, Massimiliano Gaetani, Kamilya Altynbekova, Alexander Kel, Per-Olof Berggren, Oscar Simonson, Karl-Henrik Grinnemo, Rikard Holmdahl, Sergey Rodin, Roman A. Zubarev
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
To characterize molecular changes during cell type transitions, the authors develop a method to simultaneously measure protein expression and thermal stability changes. They apply this approach to study differences between human pluripotent stem cell
Externí odkaz:
https://doaj.org/article/ea00b3040ab748c68e25909b2a8c2546
Autor:
Rasool Saghaleyni, Magdalena Malm, Noah Moruzzi, Jan Zrimec, Ronia Razavi, Num Wistbacka, Hannes Thorell, Anton Pintar, Andreas Hober, Fredrik Edfors, Veronique Chotteau, Per-Olof Berggren, Luigi Grassi, Aleksej Zelezniak, Thomas Svensson, Diane Hatton, Jens Nielsen, Jonathan L. Robinson, Johan Rockberg
Publikováno v:
Cell Reports, Vol 39, Iss 11, Pp 110936- (2022)
Summary: Recombinant protein production can cause severe stress on cellular metabolism, resulting in limited titer and product quality. To investigate cellular and metabolic characteristics associated with these limitations, we compare HEK293 clones
Externí odkaz:
https://doaj.org/article/039c0d28027d41c49243a52c9ff39b2d
Autor:
Kim Olesen, Noah Moruzzi, Ivana Bulatovic, Clifford Folmes, Ryounghoon Jeon, Ulrika Felldin, Andre Terzic, Oscar E. Simonson, Katarina Le Blanc, Cecilia Österholm, Per-Olof Berggren, Tomas Schiffer, Sergey Rodin, Andreas Tilevik, Karl-Henrik Grinnemo
Publikováno v:
Metabolism Open, Vol 13, Iss , Pp 100167- (2022)
Objective: Cell metabolism has been shown to play an active role in regulation of stemness and fate decision. In order to identify favorable culture conditions for mesenchymal stromal cells (MSCs) prior to transplantation, this study aimed to charact
Externí odkaz:
https://doaj.org/article/9256dd749929405f965859b1d2ecfd09
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12338 (2022)
Mitochondrial dynamics and bioenergetics are central to glucose-stimulated insulin secretion by pancreatic beta cells. Previously, we demonstrated that a disturbance in glucose-invoked fission impairs insulin secretion by compromising glucose catabol
Externí odkaz:
https://doaj.org/article/8ed448fcf7774b43b4a728968275e64e
Autor:
Zuheng Ma, Noah Moruzzi, Sergiu-Bogdan Catrina, Ingrid Hals, José Oberholzer, Valdemar Grill, Anneli Björklund
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e67498 (2013)
Beta cells of pancreatic islets are susceptible to functional deficits and damage by hypoxia. Here we aimed to characterize such effects and to test for and pharmacological means to alleviate a negative impact of hypoxia.Rat and human pancreatic isle
Externí odkaz:
https://doaj.org/article/a9be52734fbe4a31808b3de8e625dd3e
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33712 (2012)
BACKGROUND: Mitochondria are both the cellular powerhouse and the major source of reactive oxygen species. Coenzyme Q(10) plays a key role in mitochondrial energy production and is recognized as a powerful antioxidant. For these reasons it can be arg
Externí odkaz:
https://doaj.org/article/eff80ee25f1b48a7818c684d7b9bfdc6
Publikováno v:
Evolving Concepts in Insulin Resistance ISBN: 9781803555010
Evolving Concepts in Insulin Resistance
Evolving Concepts in Insulin Resistance
Insulin receptors (IRs) are ubiquitously expressed and essential for all cell types. Their signaling cascades are connected to key pathways involved in cell metabolism, proliferation, and differentiation, amongst others. Thus, dysregulation of IR-med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d43e869e74d1f0eb20c39d796914b8d1
https://doi.org/10.5772/intechopen.103036
https://doi.org/10.5772/intechopen.103036
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 20; Pages: 12338
Mitochondrial dynamics and bioenergetics are central to glucose-stimulated insulin secretion by pancreatic beta cells. Previously, we demonstrated that a disturbance in glucose-invoked fission impairs insulin secretion by compromising glucose catabol