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pro vyhledávání: '"Noah M. Greenwood"'
Autor:
Patricia Soto, Garrett M. Gloeb, Kaitlin A. Tsuchida, Austin A. Charles, Noah M. Greenwood, Heidi Hendrickson
Publikováno v:
Prion, Vol 17, Iss 1, Pp 55-66 (2023)
ABSTRACTMisfolding of the prion protein is central to prion disease aetiology. Although understanding the dynamics of the native fold helps to decipher the conformational conversion mechanism, a complete depiction of distal but coupled prion protein
Externí odkaz:
https://doaj.org/article/c2070d4b52264a5995454d0d3f615778
Autor:
Patricia Soto, Davis T. Thalhuber, Frank Luceri, Jamie Janos, Mason R. Borgman, Noah M. Greenwood, Sofia Acosta, Hunter Stoffel
Publikováno v:
Frontiers in Bioinformatics, Vol 3 (2024)
The Prion protein is the molecular hallmark of the incurable prion diseases affecting mammals, including humans. The protein-only hypothesis states that the misfolding, accumulation, and deposition of the Prion protein play a critical role in toxicit
Externí odkaz:
https://doaj.org/article/ecd404949b99405b86c0e805d6c1e5a4