Zobrazeno 1 - 10
of 358
pro vyhledávání: '"Noah M Hahn"'
Autor:
Max Kates, Noah M Hahn, Michael E Rezaee, Katherine M Mahon, Bruce J Trock, The-Hung Edward Nguyen, Armine K Smith, Sunil H Patel
Publikováno v:
BMJ Open, Vol 14, Iss 6 (2024)
Introduction Transurethral resection of bladder tumour (TURBT) is one of the more common procedures performed by urologists. It is often described as an ‘incision-free’ and ‘well-tolerated’ operation. However, many patients experience distres
Externí odkaz:
https://doaj.org/article/f1f90c0b15f94bda8331854b13fa698f
Autor:
Huan Wang, Nina Bhardwaj, Naoko Imai, Seunghee Kim-Schulze, Takuro Saito, Jingjing Qi, Sacha Gnjatic, Sumanta K Pal, Matthew D Galsky, Manishkumar Patel, Hui Xie, Robert Sebra, Andrew Uzilov, Jonathan Anker, Rebecca Halperin, Shingo Eikawa, Noah M Hahn
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 8 (2023)
Cisplatin-based chemotherapy has been associated with durable disease control in a small subset of patients with metastatic urothelial cancer. However, the mechanistic basis for this phenomenon has remained elusive. Antitumor immunity may underlie th
Externí odkaz:
https://doaj.org/article/55cbcba3ae0649aeb88c87f1c18bdaa7
Publikováno v:
PLoS Genetics, Vol 14, Iss 8, p e1007571 (2018)
There is growing evidence that molecular subtypes (e.g. luminal and basal subtypes) affect the prognosis and treatment response in patients with muscle invasive urinary bladder cancer (invasive urothelial carcinoma, iUC). Modeling these subtypes in p
Externí odkaz:
https://doaj.org/article/77a8e2721d6140f38d58e8863baf561f
Autor:
Costantine Albany, Noah M Hahn
Publikováno v:
Asian Journal of Andrology, Vol 16, Iss 3, Pp 359-363 (2014)
Defects within apoptotic pathways have been implicated in prostate cancer (PCa) tumorigenesis, metastatic progression and treatment resistance. A hallmark of cancers is the ability to derail apoptosis by inhibiting the apoptotic signal, reducing the
Externí odkaz:
https://doaj.org/article/9c9197f8d0134a9b93e30057dce1de29
Autor:
Hui Cai, Elena G Chiorean, Michael V Chiorean, Douglas K Rex, Bruce W Robb, Noah M Hahn, Ziyue Liu, Patrick J Loehrer, Marietta L Harrison, Yan Xu
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57081 (2013)
Only in recent years have phospholipase A2 enzymes (PLA2s) emerged as cancer targets. In this work, we report the first detection of elevated PLA2 activities in plasma from patients with colorectal, lung, pancreatic, and bladder cancers as compared t
Externí odkaz:
https://doaj.org/article/c628a348113c433b9bdfd1c4f18d630e
Autor:
Noah M. Hahn, Michael A. O'Donnell, Jason A. Efstathiou, Marianna Zahurak, Gary L. Rosner, Jeff Smith, Max R. Kates, Trinity J. Bivalacqua, Phuoc T. Tran, Daniel Y. Song, Alex S. Baras, Andres Matoso, Woonyoung Choi, Kellie N. Smith, Drew M. Pardoll, Luigi Marchionni, Bridget McGuire, Mary Grace Phelan, Burles A. Johnson, Tanya O'Neal, David J. McConkey, Tracy L. Rose, Marc Bjurlin, Emerson A. Lim, Charles G. Drake, James M. McKiernan, Israel Deutsch, Christopher B. Anderson, Donald L. Lamm, Daniel M. Geynisman, Elizabeth R. Plimack, Mark A. Hallman, Eric M. Horwitz, Essel Al-Saleem, David Y.T. Chen, Richard E. Greenberg, Alexander Kutikov, Gordon Guo, Timothy A. Masterson, Nabil Adra, Hristos Z. Kaimakliotis
Publikováno v:
European Urology. 83:486-494
Autor:
H. Josh Jang, Galen Hostetter, Alexander W. Macfarlane, Zachary Madaj, Eric A. Ross, Toshinori Hinoue, Justin R. Kulchycki, Ryan S. Burgos, Mahvish Tafseer, R. Katherine Alpaugh, Candice L. Schwebel, Rutika Kokate, Daniel M. Geynisman, Matthew R. Zibelman, Pooja Ghatalia, Peter W. Nichols, Woonbok Chung, Jozef Madzo, Noah M. Hahn, David I. Quinn, Jean-Pierre J. Issa, Michael J. Topper, Stephen B. Baylin, Hui Shen, Kerry S. Campbell, Peter A. Jones, Elizabeth R. Plimack
Publikováno v:
Clinical Cancer Research. 29:2052-2065
Purpose: On the basis of preclinical evidence of epigenetic contribution to sensitivity and resistance to immune checkpoint inhibitors (ICI), we hypothesized that guadecitabine (hypomethylating agent) and atezolizumab [anti–programmed cell death li
Autor:
Evangelia Vlachou, Andres Matoso, David McConkey, Yuezhou Jing, Burles Avner Johnson, Noah M. Hahn, Jean Hoffman-Censits
Publikováno v:
European Urology Open Science. 49:100-103
Autor:
Vamsi Parimi, Woonyoung Choi, Mingxiao Feng, Megan Fong, Jean Hoffman‐Censits, Max Kates, Kara A. Lombardo, Eva Comperat, David J. McConkey, Noah M. Hahn, Rodrigo Salgado Esteves, Andres Matoso
Publikováno v:
Histopathology. 82:991-1002
Publikováno v:
Urologic Oncology: Seminars and Original Investigations. 41:27-34
Non-muscle-invasive bladder cancer is one of the most common malignancies. Patients with intermediate-risk or high-risk disease can be treated with intravesical Bacillus Calmette-Guerin, a vaccine against tuberculosis. However, many of these patients