Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Noah J. Tubo"'
Autor:
Noah J Tubo, Marc A Wurbel, Trevor T Charvat, Thomas J Schall, Matthew J Walters, James J Campbell
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50498 (2012)
A goal for developers of immunomodulatory drugs has long been a systemically administered small molecule that can selectively inhibit inflammation in specific tissues. The chemokine receptor CCR9 is an attractive target for this approach, as entry of
Externí odkaz:
https://doaj.org/article/d1cf89c142a74bd1aa84b7f37b5e451a
Autor:
Marc K. Jenkins, Noah J. Tubo
Publikováno v:
Trends in Immunology. 35:591-596
The adaptive immune system protects its host from a myriad of pathogens. This ability stems from a vast set of lymphocytes, each with a different antigen receptor, a small number of which will bind to antigens derived from a given pathogen. Although
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9abbd93bd9b9b5ec1c9b514fa2f89353
https://doi.org/10.1016/j.it.2014.09.008
https://doi.org/10.1016/j.it.2014.09.008
Autor:
Thomas S. Kupper, James Campbell, Robert C. Fuhlbrigge, Suzanne T. Nizza, Marianne Boes, Noah J. Tubo, Bernard Malissen, Bryan Vander Lugt
Publikováno v:
The Journal of Immunology. 191:3119-3127
CCR7−/− mice exhibit profound anomalies in lymph node and spleen architecture, which complicates the study of CCR7-mediated T cell trafficking in vivo. To circumvent this problem, we established in vivo models in which wild-type and CCR7−/− p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88ce22ab086f41e5ec5dfa0b26f74614
https://doi.org/10.4049/jimmunol.1200938
https://doi.org/10.4049/jimmunol.1200938
Autor:
Ryan W. Nelson, Jonathan L. Linehan, Marc K. Jenkins, Justin J. Taylor, Noah J. Tubo, Eric S. Huseby, Sing Sing Way, Antonio J. Pagán, James M. Ertelt
Publikováno v:
Cell. 153:785-796
SummaryA naive CD4+ T cell population specific for a microbial peptide:major histocompatibility complex II ligand (p:MHCII) typically consists of about 100 cells, each with a different T cell receptor (TCR). Following infection, this population produ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0a211448a7cb6f966d7fdd7b8511ce0
https://doi.org/10.1016/j.cell.2013.04.007
https://doi.org/10.1016/j.cell.2013.04.007
Autor:
Dmitri I. Kotov, Antonio J. Pagán, Michael F. Goldberg, Marc K. Jenkins, Brian T. Fife, Noah J. Tubo
Publikováno v:
Science (New York, N.Y.). 351(6272)
All T cells can remember One of the hallmarks of adaptive immunity is that T and B lymphocytes “remember” previous infections, protecting the host from subsequent infections. When T cells respond to a pathogen, they proliferate, and a fraction of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48787b1e8aa2c8159d152e4313536b31
https://pubmed.ncbi.nlm.nih.gov/26823430
https://pubmed.ncbi.nlm.nih.gov/26823430
Publikováno v:
The American Journal of Pathology. 178:2496-2503
Inflamed skin contains CD4 T-cell subsets that express chemokine receptors CCR4, CCR6, and/or CCR10. Prior attempts to reveal the distinct role(s) of each receptor in T-cell trafficking to skin have not produced a coherent story. Different conclusion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3102454192b7ba7e167e60a8d33f2b93
https://doi.org/10.1016/j.ajpath.2011.02.031
https://doi.org/10.1016/j.ajpath.2011.02.031
Autor:
L. M. Butler, O. Pabst, J. Huehn, B. Wahl, K. Aalto, T. Amagai, K. Kunizawa, H. Kagechika, A. Blaschitz, D. M. Otte, W. Maier, T. Glant, M. H. Jang, T. Kobezda, T. Higuchi, N. Hayasaka, S. I. Hammerschmidt, N. Higashi, A. Angyal, J. Alferink, A. Yokota, U. Syrbe, O. Yoshie, P. Knolle, Y. Fu, L. Nikitina, M. Itoi, E. Fusaoka-Nishioka, E. Umemoto, G. E. Rainger, K. Mori, M. Nishimura, E. Kivi, C. Egelston, B. Schürmann, B. Szilagyi, M. Schimek, B. Nuernberg, S. Jin, M. Hashizume, Y. Nishimura, Y. Ohoka, K. Poppensieker, S. N. Syed, E. Kremmer, T. Kinashi, M. Koyama, J. Keuschnigg, K. Shimano, Noah J. Tubo, M. Mihara, S. Song, S. Jalkanen, H. Yagi, H. C. Jeffery, M. Zhu, M. Nakajima, L. Birnbaumer, M. Maksimow, H. Takeuchi, D. D. Le, P. Dresing, R. Kannagi, N. Sato, A. Waisman, M. Prinz, T. Henttinen, G. B. Nash, T. Salminen, T. Sugita, M. Masutani, James Campbell, M. F. Schroeter, T. Tanaka, K. Hieshima, Y. Nymalm, J. Hecht, T. Imai, K. Elima, M. Salmi, A. Mildner, Y. Higuchi, M. Ahrendt, Y. Wang, I. Förster, A. Zimmer, R. Yamaoka, T. Kubo, S. Scheu, C. Kato, A. Limmer, Y. Maeda, H. M. McGettrick, M. Iwata, A. Menning, C. D. Buckley, R. P. Piekorz, K. Chiba, J. E. Gessner, U. Bode, H. Ahammer, K. Tateishi, A. Filer, K. Mikecz, B. A. Ratsch, R. Förster, S. Ichimiya, A. K. Shirakawa, A. Fukunari, M. Pink, L. Klotz, M. Miyasaka, S. R. Ali, K. Sugahara, T. Katakai, R. E. Schmidt, G. Dohr, T. Nakayama, K. Wiege, P. Crocker, Y. Endo, N. Hogg, R. L. Wheat, D. J. Blackbourn, T. Irimura, Y. Uchiyama, A. Shigeta, A. Hamann, S. Floess, M. Sue, P. Sedlmayr, N. Tsukamoto, K. Katagiri, H. Elovaara, S. Yonekura, A. Kyusai
Publikováno v:
International Immunology. 22:ii61-ii66
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af0a04b8f1b4e4bb64cf9854eff543cb
https://doi.org/10.1093/intimm/dxq115
https://doi.org/10.1093/intimm/dxq115
Autor:
Maria Köllnberger, Amy J. Wagers, Irina Knezevic-Maramica, Tobias Junt, E. Ashley Moseman, Steffen Massberg, Noah J. Tubo, Irina B. Mazo, Ulrich H. von Andrian, Ines V. Huff, Patrick Schaerli
Publikováno v:
Cell. 131(5):994-1008
SummaryConstitutive egress of bone marrow (BM)-resident hematopoietic stem and progenitor cells (HSPCs) into the blood is a well-established phenomenon, but the ultimate fate and functional relevance of circulating HSPCs is largely unknown. We show t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d16c04e7da407a88c41c222e5eba5a81
Autor:
Federico Baruffaldi, Jeffrey S. Vervacke, Thomas S. Griffith, Marco Pravetoni, Mark D. Distefano, Megan Laudenbach, Noah J. Tubo, Philip J. Titcombe, Daniel L. Mueller
Translation of therapeutic vaccines for addiction, cancer, or other chronic noncommunicable diseases has been slow because only a small subset of immunized subjects achieved effective Ab levels. We hypothesize that individual variability in the numbe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9020e71078298202481309de7cdc56c
https://europepmc.org/articles/PMC4458396/
https://europepmc.org/articles/PMC4458396/
Autor:
Marc K. Jenkins, H. Hamlet Chu, Dorian B. McGavern, Ki-Duk Song, Jasmin Herz, Amy Palin, Ekaterina Zvezdova, Jan Lee, Li Qi Li, Noah J. Tubo, Su Jin Hwang, Paul E. Love, Julia Pinkhasov, Marion Pepper, Renaud Lesourne
Publikováno v:
Nature Communications
The T-cell antigen receptor (TCR) complex contains 10 copies of a di-tyrosine Immunoreceptor-Tyrosine-based-Activation-Motif (ITAM) that initiates TCR signalling by recruiting protein tyrosine kinases. ITAM multiplicity amplifies TCR signals, but the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::681e55d18b74262c89b84cbb9aad132d
http://europepmc.org/articles/PMC4428620
http://europepmc.org/articles/PMC4428620