Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Noah J. Smith"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Progressive emphysema often leads to end-stage lung disease. Most mouse models of emphysema are typically modest (i.e. cigarette smoke exposure), and changes over time are difficult to quantify. The tracheal porcine pancreatic elastase model
Externí odkaz:
https://doaj.org/article/1bb9a3d519304601b7f682915fe8b383
Autor:
Andrew J. Devine, Noah J. Smith, Rashika Joshi, Qiang Fan, Michael T. Borchers, Geremy C. Clair, Joshua N. Adkins, Brian M. Varisco
Chymotrypsin-like elastase 1 (CELA1) is a serine protease that is neutralized by α1-antitrypsin (AAT) and prevents emphysema in a murine antisense oligonucleotide model of AAT-deficient emphysema. Mice with genetic ablation of AAT do not have emphys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::090b972a36664a86938a32ed04ee9a9f
https://doi.org/10.21203/rs.3.rs-2617812/v1
https://doi.org/10.21203/rs.3.rs-2617812/v1
