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pro vyhledávání: '"Noah J Goff"'
Autor:
Noah J Goff, Manon Brenière, Christopher J Buehl, Abinadabe J de Melo, Hana Huskova, Takashi Ochi, Tom L Blundell, Weifeng Mao, Kefei Yu, Mauro Modesti, Katheryn Meek
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 2022, pp.gkac913. ⟨10.1093/nar/gkac913⟩
Nucleic Acids Research, 2022, pp.gkac913. ⟨10.1093/nar/gkac913⟩
Funder: French National Cancer Institute
DNA double strand breaks (DSBs) are induced by external genotoxic agents (ionizing radiation or genotoxins) or by internal processes (recombination intermediates in lymphocytes or by replication errors).
DNA double strand breaks (DSBs) are induced by external genotoxic agents (ionizing radiation or genotoxins) or by internal processes (recombination intermediates in lymphocytes or by replication errors).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b28fa61ac060a70e6459d4b044358a9e
https://www.hal.inserm.fr/inserm-03825783/file/gkac913.pdf
https://www.hal.inserm.fr/inserm-03825783/file/gkac913.pdf
Autor:
Christopher J. Buehl, Noah J. Goff, Steven W. Hardwick, Martin Gellert, Tom L. Blundell, Wei Yang, Amanda K. Chaplin, Katheryn Meek
Publikováno v:
Molecular Cell. 83:698-714.e4
Autor:
Christopher J. Buehl, Noah J. Goff, Steven W. Hardwick, Martin Gellert, Tom L. Blundell, Wei Yang, Amanda K. Chaplin, Katheryn Meek
Publikováno v:
SSRN Electronic Journal.
Autor:
Antonia Kefala Stavridi, Virginie Ropars, Shikang Liang, Amanda K. Chaplin, Jean-Baptiste Charbonnier, Dimitri Y. Chirgadze, Steven W. Hardwick, Noah J Goff, Tom L. Blundell, Taiana Maia de Oliveira, Katheryn Meek, Christopher J. Buehl
Non-homologous end joining (NHEJ) is one of two critical mechanisms utilized in humans to repair DNA double-strand breaks (DSBs). Unrepaired or incorrect repair of DSBs can lead to apoptosis or cancer. NHEJ involves several proteins, including the Ku
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff291ec26fc79784cdf65b31e9d37f60
Autor:
Lan Liu, Xuemin Chen, Jun Li, Huaibin Wang, Christopher J. Buehl, Noah J. Goff, Katheryn Meek, Wei Yang, Martin Gellert
Publikováno v:
Mol Cell
The DNA-dependent protein kinase (DNA-PK) initially protects broken DNA ends, but then promotes their processing during non-homologous end-joining (NHEJ). Before ligation by NHEJ, DNA hairpin ends generated during V(D)J recombination must be opened b