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of 4
pro vyhledávání: '"Noah G. Moran"'
Autor:
Yang Xu, Han Han, Ian Cooney, Yuxuan Guo, Noah G. Moran, Nathan R. Zuniga, John C. Price, Christopher P. Hill, Peter S. Shen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
The p97 unfoldase is an essential and abundant enzyme that segregates its substrates from macromolecular complexes and organelle membranes. Here, authors determined the structure of human p97 in the act of unfolding an authentic substrate.
Externí odkaz:
https://doaj.org/article/2b0aaf042b8f4253a15fabdae3c83fbf
Autor:
Yang Xu, Han Han, Ian Cooney, Yuxuan Guo, Noah G. Moran, Nathan R. Zuniga, John C. Price, Christopher P. Hill, Peter S. Shen
Publikováno v:
Nature communications. 13(1)
The p97 AAA+ATPase is an essential and abundant regulator of protein homeostasis that plays a central role in unfolding ubiquitylated substrates. Here we report two cryo-EM structures of human p97 in complex with its p47 adaptor. One of the conformat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63f1c2a4029e0d174761a5bf74674d96
https://pubmed.ncbi.nlm.nih.gov/35552390
https://pubmed.ncbi.nlm.nih.gov/35552390
Autor:
Zuniga, Nathan R.1 (AUTHOR), Earls, Noah E.1 (AUTHOR), Denos, Ariel E. A.1 (AUTHOR), Elison, Jared M.1 (AUTHOR), Jones, Benjamin S.1 (AUTHOR), Smith, Ethan G.1 (AUTHOR), Moran, Noah G.1 (AUTHOR), Broce, Katie L.1 (AUTHOR), Romero, Gerome M.1 (AUTHOR), Hyer, Chad D.1 (AUTHOR), Wagstaff, Kimberly B.1 (AUTHOR), Almughamsi, Haifa M.2 (AUTHOR), Transtrum, Mark K.3 (AUTHOR), Price, John C.1 (AUTHOR) drjohncprice@gmail.com
Publikováno v:
PLoS Computational Biology. 12/12/2024, Vol. 20 Issue 12, p1-29. 29p.
Autor:
Xu, Yang, Han, Han, Cooney, Ian, Guo, Yuxuan, Moran, Noah G., Zuniga, Nathan R., Price, John C., Hill, Christopher P., Shen, Peter S.
Publikováno v:
Nature Communications; 5/12/2022, Vol. 13 Issue 1, p1-8, 8p