Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Noah Depner"'
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-29 (2020)
Abstract Advances in CRISPR technology have immensely improved our ability to manipulate nucleic acids, and the recent discovery of the RNA-targeting endonuclease Cas13 adds even further functionality. Here, we show that Cas13 works efficiently in Dr
Externí odkaz:
https://doaj.org/article/db416ad19e4748d6986e6a13e070e095
Autor:
Andrew J. Kukor, Noah Depner, Isabelle Cai, John L. Tucker, Jeffrey C. Culhane, Jason E. Hein
Publikováno v:
Chemical Science. 13:10765-10772
A novel enantioselective route to tetrabenazine has been developed using continuous CIDT in a multiwell crystallization/racemization device outfitted with real-time HPLC to visualize and control the dynamic process.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cc1b71ed826cb7f0357394c60e4856d
https://doi.org/10.1039/d2sc01825j
https://doi.org/10.1039/d2sc01825j
Autor:
Derrick L. J. Clive, Damian Szymor-Pietrzak, Anaïs Pagès, Muhammad Naseem Khan, Noah Depner, Ajay Kumar
Publikováno v:
The Journal of Organic Chemistry. 86:619-631
meta-Aminophenols are formed by the action of DBU on 3-amino-2-chlorocyclohex-2-en-1-ones at room temperature in MeCN. The chloro compounds are generated by treating 3-aminocyclohex-2-en-1-ones with the easily prepared halogenating agent BnNMe3·ICl2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83d97c7716e75b635e7df6867213032e
https://doi.org/10.1021/acs.joc.0c02284
https://doi.org/10.1021/acs.joc.0c02284
Autor:
Andrew J, Kukor, Noah, Depner, Isabelle, Cai, John L, Tucker, Jeffrey C, Culhane, Jason E, Hein
Publikováno v:
Chemical science. 13(36)
A multi-well continuous CIDT approach with inline racemization of the solution phase is presented. Using two in-house built PATs and a flow reactor, we were able to successfully crystallize an enantiopure salt of TBZ, the active metabolite of the tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::55b1993fd9ee0059dc257c3dfae1e9c3
https://pubmed.ncbi.nlm.nih.gov/36320713
https://pubmed.ncbi.nlm.nih.gov/36320713
Publikováno v:
Genome Biology
Genome Biology, Vol 21, Iss 1, Pp 1-29 (2020)
Genome Biology, Vol 21, Iss 1, Pp 1-29 (2020)
SummaryAdvances in CRISPR technology have immensely improved our ability to manipulate nucleic acids, and the recent discovery of the RNA-targeting endonuclease Cas13 adds even further functionality. Here, we show that Cas13 works efficiently in Dros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6750f8e02ee6142a97e4117bd34313f
https://pubmed.ncbi.nlm.nih.gov/33203452
https://pubmed.ncbi.nlm.nih.gov/33203452