Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Noah C. Helderman"'
Autor:
Anne-Sophie van der Werf't Lam, Noah C. Helderman, Arnoud Boot, Diantha Terlouw, Hans Morreau, Hailian Mei, Rebecca E.E. Esveldt-van Lange, Inge M.M. Lakeman, Christi J. van Asperen, Emmelien Aten, Nandy Hofland, Pia A.M. de Koning Gans, Emily Rayner, Carli Tops, Niels de Wind, Tom van Wezel, Maartje Nielsen
Publikováno v:
Experimental and Molecular Pathology, Vol 140, Iss , Pp 104940- (2024)
Functional analyses are the main method to classify mismatch repair (MMR) gene variants of uncertain significance (VUSs). However, the pathogenicity remains unclear for many variants because of conflicting results between clinical, molecular, and fun
Externí odkaz:
https://doaj.org/article/495ee08f0dc6450c81f1b9f564d08794
Autor:
Katarina D. Andini, Maartje Nielsen, Manon Suerink, Noah C. Helderman, Jan Jacob Koornstra, Aysel Ahadova, Matthias Kloor, Marian J.E. Mourits, Klaas Kok, Rolf H. Sijmons, Sanne W. Bajwa–ten Broeke
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Carriers of any pathogenic variant in one of the MMR genes (path_MMR carriers) were traditionally thought to be at comparable risk of developing a range of different malignancies, foremost colorectal cancer (CRC) and endometrial cancer. However, it i
Externí odkaz:
https://doaj.org/article/15769ffda77f4c1a9b30087e71c7b542
Autor:
Noah c. Helderman, Anne-Sophie Van Der Werf-’T Lam, Hans Morreau, Arnoud Boot, Tom Van Wezel, Maartje Nielsen, Diantha Terlouw, Sanne W. Bajwa-ten Broeke, Mar Rodríguez-Girondo, Demi van Egmond, Alexandra M.J. Langers, Monique E. van Leerdam, Emily Rayner, Christi J. van Asperen, Liselotte P. van Hest, Hans J.P. Gille, Floor A.M. Duijkers, Anja Wagner, Ellis L. Eikenboom, Tom G.W. Letteboer, Mirjam M. de Jong, Fonnet E. Bleeker, Encarna B. Gomez Garcìa, Manon Suerink, Carli M. Tops, Niels de Wind
Publikováno v:
MSH6 TUMOR GROUP 2023, ' Molecular Profile of MSH6-Associated Colorectal Carcinomas Shows Distinct Features From Other Lynch Syndrome–Associated Colorectal Carcinomas ', Gastroenterology, vol. 165, no. 1, pp. 271-274.e2 . https://doi.org/10.1053/j.gastro.2023.03.198
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1acb9f5b21ff316ff9b4e61fd4dd4b08
http://www.scopus.com/inward/record.url?scp=85160215499&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85160215499&partnerID=8YFLogxK
Autor:
Maartje Nielsen, Diantha Terlouw, Manon Suerink, Sanne W. ten Broeke, Anne-Sophie van der Werf-’ t Lam, Noah C. Helderman, Tom van Wezel, Hans Morreau
Publikováno v:
Critical Reviews in Oncology/Hematology, 163. ELSEVIER SCIENCE INC
Lynch syndrome (LS) is a hereditary cancer syndrome that accounts for 3% of all new colorectal cancer (CRC) cases. Patients carry a germline pathogenic variant in one of the mismatch repair (MMR) genes (MLH1, MSH2, MSH6 or PMS2), which encode protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11bc023e9d0fe809477fdc3a4839975c
https://doi.org/10.1016/j.critrevonc.2021.103338
https://doi.org/10.1016/j.critrevonc.2021.103338