Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Noah B. Goodson"'
Autor:
Michael L. Kaufman, Noah B. Goodson, Emma Office, Michael Schwanke, Ko Uoon Park, Joseph A. Brzezinski, Austin Hensley, Kenneth Jones, Joy Abraham, Sophia R Schneider
Publikováno v:
Development
During retinal development, a large subset of progenitors upregulates the transcription factor Otx2, which is required for photoreceptor and bipolar cell formation. How these retinal progenitor cells initially activate Otx2 expression is unclear. To
Autor:
Noah B. Goodson, Jason S. Silver, Joseph A. Brzezinski, Ko U. Park, William W. Hauswirth, Vince A. Chiodo
Publikováno v:
Dev Biol
The transcription factors Prdm1 (Blimp1) and Vsx2 (Chx10) work downstream of Otx2 to regulate photoreceptor and bipolar cell fates in the developing retina. Mice that lack Vsx2 fail to form bipolar cells while Prdm1 mutants form excess bipolars at th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eb5cf52c4798a5e1e4fc97211dfbcdf
https://europepmc.org/articles/PMC7386070/
https://europepmc.org/articles/PMC7386070/
Publikováno v:
Development (Cambridge, England). 147(13)
The transcription factor OTX2 is required for photoreceptor and bipolar cell formation in the retina. It directly activates the transcription factors
Publikováno v:
Development.
The transcription factor Otx2 is required for photoreceptor and bipolar cell formation in the retina. It directly activates the transcription factors Prdm1 and Vsx2 through cell type-specific enhancers. Prdm1 and Vsx2 work in opposition, such that Pr
Publikováno v:
Journal of Comparative Neurology. 525:1743-1755
The ionotropic serotonin receptor, 5-HT3 , is expressed by many developing neurons within the central nervous system. Since the olfactory epithelium continues to generate new olfactory sensory neurons (OSNs) throughout life, we investigated the possi
Autor:
Deepak A. Lamba, Noah B. Goodson, Michael L. Kaufman, Joseph A. Brzezinski, Ko Uoon Park, Stephanie M. Bersie, Shereen Chew, Kenneth L. Jones
Publikováno v:
Dev Biol
Uncovering the gene regulatory networks that control cone photoreceptor formation has been hindered because cones only make up a few percent of the retina and form asynchronously during development. To overcome these limitations, we used a γ-secreta
Autor:
Britni E Lynch, Chris G. Dulla, Noah B. Goodson, David H. Gire, Jennifer N. Bourne, Nathan E. Schoppa, Joseph D. Zak
The mammalian olfactory bulb has presented a challenging system for understanding information processing, in part because the bulb largely lacks the topographical ordering of neurons that promotes processes such as lateral inhibition. Here we have us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f0854e07414373eaa77960bb8ec422a
Publikováno v:
Neuroscience. 292:112-117
Caffeine works through a variety of complex mechanisms to exert an often bidirectional set of functional and structural neurological changes in vertebrates. We investigated the effects of chronic caffeine exposure on functional recovery of the dorsal
Publikováno v:
eNeuro
Glutamatergic transmission in the brain typically occurs at well-defined synaptic connections, but increasing evidence indicates that neural excitation can also occur through activation of “extrasynaptic” glutamate receptors. Here, we investigate
Publikováno v:
The Journal of comparative neurology. 525(7)
The ionotropic serotonin receptor, 5-HT(3), is expressed by many developing neurons within the central nervous system. Since the olfactory epithelium continues to generate new olfactory sensory neurons (OSNs) throughout life, we investigated the poss