Maternal and paternal exercise regulate offspring metabolic health and beta cell phenotype

Autor: Ana Barbara Alves-Wagner, Kristin I Stanford, Noah B Prince, Kawai So, Joram D Mul, Ercument Dirice, Michael F Hirshman, Rohit N Kulkarni, Laurie J Goodyear

Publikováno v: BMJ Open Diabetes Research & Care, Vol 8, Iss 1 (2020)

ObjectivePoor maternal and paternal environments increase the risk for obesity and diabetes in offspring, whereas maternal and paternal exercise in mice can improve offspring metabolic health. We determined the effects of combined maternal and patern

Externí odkaz: https://doaj.org/article/5e83270f70b5476c882a997a57346fc1

Placental superoxide dismutase 3 mediates benefits of maternal exercise on offspring health

Autor: Joji Kusuyama, Jayonta Bhattacharjee, Royce H. Conlin, Mary-Elizabeth Patti, Mette Bjerre, Per Ovesen, Yang Xia, Yang Xiudong, Chisayo Kozuka, Céline Aguer, Brent G. Albertson, Kristi B. Adamo, Niels Jessen, Nathan S. Makarewicz, Roeland J.W. Middelbeek, Emily M. Miele, Ana Barbara Alves-Wagner, Michael F. Hirshman, Toshihisa Hatta, Jens Fuglsang, Laurie J. Goodyear, Eva Nozik-Grayck, Shio Kobayashi, Noah B. Prince, Magnus Møller, Léa Garneau

Publikováno v: Kusuyama, J, Alves-Wagner, A B, Conlin, R H, Makarewicz, N S, Albertson, B G, Prince, N B, Kobayashi, S, Kozuka, C, Møller, M, Bjerre, M, Fuglsang, J, Miele, E, Middelbeek, R J W, Xiudong, Y, Xia, Y, Garneau, L, Bhattacharjee, J, Aguer, C, Patti, M E, Hirshman, M F, Jessen, N, Hatta, T, Ovesen, P G, Adamo, K B, Nozik-Grayck, E & Goodyear, L J 2021, ' Placental superoxide dismutase 3 mediates benefits of maternal exercise on offspring health ', Cell Metabolism, vol. 33, no. 5, pp. 939-956.e8 . https://doi.org/10.1016/j.cmet.2021.03.004
Cell Metab

Poor maternal diet increases the risk of obesity and type 2 diabetes in offspring, adding to the ever-increasing prevalence of these diseases. In contrast, we find that maternal exercise improves the metabolic health of offspring, and here, we demons

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c00ce2aca82b8c6b5314dbec1a766be
https://pubmed.ncbi.nlm.nih.gov/33846589

Maternal Exercise Improves Glucose Tolerance in Female Offspring

Autor: Kawai So, Hirokazu Takahashi, Kristen M. Getchell, Min-Young Lee, Laurie J. Goodyear, Ana Barbara Alves-Wagner, Michael F. Hirshman, Noah B. Prince, Kristin I. Stanford, Adam C. Lehnig

Publikováno v: Diabetes

Poor maternal diet can lead to metabolic disease in offspring, whereas maternal exercise may have beneficial effects on offspring health. In this study, we determined ifmaternal exercise could reverse the detrimental effects of maternal high-fat feed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beb7234adde92050d89081ca5e932984
https://doi.org/10.2337/db17-0098

Maternal and Paternal Exercise Regulates Offspring Metabolic Health and Beta-Cell Phenotype

Autor: Jia Zheng, Kristin I. Stanford, Joram D. Mul, Rohit N. Kulkarni, Laurie J. Goodyear, Kawai So, Noah B. Prince, Michael F. Hirshman, Ercument Dirice, Ana B.A. Wagner

Publikováno v: Diabetes. 67

Maternal and paternal environment are critical factors in determining risk for obesity and diabetes in offspring. Maternal exercise in mice can prevent the detrimental effects of maternal high-fat feeding on offspring metabolic health, whereas the ef

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4b34ceeb6bd488a41c4c7699ed1be770
https://doi.org/10.2337/db18-64-or