Linking human cerebral and ocular waste clearance: Insights from tear fluid and ultra-high field MRI

Autor: Merel M. van der Thiel, Nienke van de Sande, Anouk Meeusen, Gerhard S. Drenthen, Alida A. Postma, Rudy M.M.A. Nuijts, Noa van der Knaap, Inez H.G.B. Ramakers, Carroll A.B. Webers, Walter H. Backes, Marlies Gijs, Jacobus F.A. Jansen

Publikováno v: Neurobiology of Disease, Vol 203, Iss , Pp 106730- (2024)

Impaired cerebral waste clearance (i.e., glymphatics) is evident in aging and neurodegenerative disorders, such as Alzheimer's disease, where an impaired waste clearance system could be related to the accumulation of pathological proteins (e.g., tau)

Externí odkaz: https://doaj.org/article/cbf0cd53e07e4483a0497655f416dcb7

Implications of Post-recanalization Perfusion Deficit After Acute Ischemic Stroke

Autor: Aad Van der Lugt, Bart Franx, Charles Majoie, Rick Dijkhuizen, Noa Van der Knaap

Publikováno v: on behalf of the CONTRAST consortium 2023, ' Implications of Post-recanalization Perfusion Deficit After Acute Ischemic Stroke : a Scoping Review of Clinical and Preclinical Imaging Studies ', Translational Stroke Research . https://doi.org/10.1007/s12975-022-01120-6

The goal of reperfusion therapy for acute ischemic stroke (AIS) is to restore cerebral blood flow through recanalization of the occluded vessel. Unfortunately, successful recanalization does not always result in favorable clinical outcome. Post-recan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04f83442edf6970ec2316789790091ea
https://doi.org/10.1007/s12975-022-01120-6