Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Noa Roitenberg"'
Autor:
Hana Boocholez, Filipa Carvalhal Marques, Amir Levine, Noa Roitenberg, Atif Ahmed Siddiqui, Huadong Zhu, Lorna Moll, Danielle Grushko, Reut Bruck Haimson, Tayir Elami, Ehud Cohen
Publikováno v:
Cell Reports, Vol 38, Iss 6, Pp 110350- (2022)
Summary: The protein homeostasis (proteostasis) network (PN) encompasses mechanisms that maintain proteome integrity by controlling various biological functions. Loss of proteostasis leads to toxic protein aggregation (proteotoxicity), which underlie
Externí odkaz:
https://doaj.org/article/8b87583fd0624601b3339e66c187d358
Autor:
Lorna Moll, Noa Roitenberg, Michal Bejerano-Sagie, Hana Boocholez, Filipa Carvalhal Marques, Yuli Volovik, Tayir Elami, Atif Ahmed Siddiqui, Danielle Grushko, Adi Biram, Bar Lampert, Hana Achache, Tommer Ravid, Yonatan B Tzur, Ehud Cohen
Publikováno v:
eLife, Vol 7 (2018)
Although aging-regulating pathways were discovered a few decades ago, it is not entirely clear how their activities are orchestrated, to govern lifespan and proteostasis at the organismal level. Here, we utilized the nematode Caenorhabditis elegans t
Externí odkaz:
https://doaj.org/article/b31f6b8500b049b2928dc3c11f46757c
Autor:
Anna Mellul, Haya Chahine, Maya Braun, Lena Qawasmi, Danielle Share, Ehud Cohen, Irene Guberman, Noa Roitenberg, Yuval Tabach, Olli Matilainen, Susana M. D. A. Garcia, Doron Stupp, Emiliano Cohen, Lamis Naddaf
Publikováno v:
Journal of Molecular Biology. 431:1711-1728
Myotonic dystrophy type 1 is an autosomal-dominant inherited disorder caused by the expansion of CTG repeats in the 3' untranslated region of the DMPK gene. The RNAs bearing these expanded repeats have a range of toxic effects. Here we provide eviden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2cc5dd991dc9c459b3066dabd7235e3
https://doi.org/10.1016/j.jmb.2019.03.003
https://doi.org/10.1016/j.jmb.2019.03.003
Autor:
Hana Boocholez, Filipa Carvalhal Marques, Amir Levine, Noa Roitenberg, Atif Ahmed Siddiqui, Huadong Zhu, Lorna Moll, Danielle Grushko, Reut Bruck Haimson, Tayir Elami, Ehud Cohen
Publikováno v:
Cell Reports, Vol 38, Iss 6, Pp 110350-(2022)
Summary: The protein homeostasis (proteostasis) network (PN) encompasses mechanisms that maintain proteome integrity by controlling various biological functions. Loss of proteostasis leads to toxic protein aggregation (proteotoxicity), which underlie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81cda9b431bd4d871a1ec19c41e26e9d
https://pubmed.ncbi.nlm.nih.gov/35139369
https://pubmed.ncbi.nlm.nih.gov/35139369
Autor:
Noa Roitenberg, Ehud Cohen
Publikováno v:
Trends in cell biology. 29(12)
The proteostasis network (PN) is a nexus of mechanisms that act in concert to maintain the integrity of the proteome. Efficiency of the PN declines with age, resulting in the accumulation of misfolded proteins, and in some cases in the development of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0062e98bc98ff4e8f4290aba000ef70f
https://pubmed.ncbi.nlm.nih.gov/31669295
https://pubmed.ncbi.nlm.nih.gov/31669295
Autor:
Noa Roitenberg, Yuli Volovik, Danielle Grushko, Filipa Carvalhal Marques, Adi Biram, Atif Ahmed Siddiqui, Yonatan B Tzur, Tayir Elami, Michal Bejerano-Sagie, Hana Boocholez, Lorna Moll, Tommer Ravid, Hana Achache, Ehud Cohen, Bar Lampert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab36657bf8d81717229034fb90b3bf8b
https://doi.org/10.7554/elife.38635.035
https://doi.org/10.7554/elife.38635.035
Autor:
Adi Biram, Tayir Elami, Tommer Ravid, Danielle Grushko, Filipa Carvalhal Marques, Hana Achache, Yonatan B Tzur, Atif Ahmed Siddiqui, Noa Roitenberg, Hana Boocholez, Yuli Volovik, Lorna Moll, Michal Bejerano-Sagie, Ehud Cohen, Bar Lampert
Publikováno v:
eLife, Vol 7 (2018)
Although aging-regulating pathways were discovered a few decades ago, it is not entirely clear how their activities are orchestrated, to govern lifespan and proteostasis at the organismal level. Here, we utilized the nematode Caenorhabditis elegans t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2409f4279fec04da59f0b3e27053162
https://elifesciences.org/articles/38635
https://elifesciences.org/articles/38635
Autor:
Ludmila Golodetzki, Yuval Nevo, Tayir Elami, Noa Roitenberg, Ehud Cohen, Hana Boocholez, Filipa Carvalhal Marques, Michal Bejerano-Sagie, Lorna Moll
Reducing insulin/IGF-1 signaling (IIS) extends lifespan, promotes protein homeostasis (proteostasis), and elevates stress resistance of worms, flies, and mammals. How these functions are orchestrated across the organism is only partially understood.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3b368211bb393e8b4a3a11987413673
https://europepmc.org/articles/PMC6073070/
https://europepmc.org/articles/PMC6073070/